The belly rules the nose: feeding state-dependent modulation of peripheral chemosensory responses.

Abstract:

:Feeding history and the presence of food dramatically alter chemosensory behaviors. Recent results indicate that internal nutritional state can gate peripheral gustatory and olfactory sensory responses to affect behavior. Focusing primarily on recent work in C. elegans and Drosophila, I describe the neuromodulatory mechanisms that translate feeding state information into changes in chemosensory neuron response properties and behavioral output.

journal_name

Curr Opin Neurobiol

authors

Sengupta P

doi

10.1016/j.conb.2012.08.001

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

68-75

issue

1

eissn

0959-4388

issn

1873-6882

pii

S0959-4388(12)00121-3

journal_volume

23

pub_type

杂志文章,评审
  • Neural progenitors and stem cells: mechanisms of progenitor heterogeneity.

    abstract::Heterogeneity among progenitor cells in the vertebrate nervous system has been documented with increasing frequency over the past few years. It has become clear that differences in progenitor cells help to determine when and how they respond to environmental signals. More recent studies have begun to elucidate the mol...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-4388(98)80006-8

    authors: Lillien L

    更新日期:1998-02-01 00:00:00

  • It takes a seasoned bird to be a good listener: communication between the sexes.

    abstract::Birds commonly use sound for communication between the sexes. In many songbird species, only males sing and there are pronounced sex differences in the neural song control circuits. By contrast, the auditory circuitry is largely similar in males and females. Both sexes learn to recognize vocalizations heard as juvenil...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2016.01.005

    authors: Brenowitz EA,Remage-Healey L

    更新日期:2016-06-01 00:00:00

  • A circadian clock nanomachine that runs without transcription or translation.

    abstract::The biochemical basis of circadian timekeeping is best characterized in cyanobacteria. The structures of its key molecular players, KaiA, KaiB, and KaiC are known and these proteins can reconstitute a remarkable circadian oscillation in a test tube. KaiC is rhythmically phosphorylated and its phospho-status is a marke...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2013.02.012

    authors: Egli M,Johnson CH

    更新日期:2013-10-01 00:00:00

  • Learning in sensorimotor circuits.

    abstract::The study of plasticity in the central nervous system is a major and very dynamic neuroscience research field with enormous clinical potential. Considerable advances in this field have been made during the past 10 years. It now appears that most circuits in the brain and spinal cord show plasticity and that they can b...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2004.10.009

    authors: Schouenborg J

    更新日期:2004-12-01 00:00:00

  • Bottom-up and top-down modulation of multisensory integration.

    abstract::Sensory perception in the real world requires proper integration of different modality inputs. Process of multisensory integration is not uniform. It varies from individual to individual and changes at different behavioral states of the animal. What factors affect multisensory integration? How does the mammalian brain...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2018.05.002

    authors: Choi I,Lee JY,Lee SH

    更新日期:2018-10-01 00:00:00

  • On the cerebellum and motor learning.

    abstract::A critical review of the role of the cerebellum in motor learning is presented. Specifically, the hypothesis that the climbing fibers that issue from the inferior olive serve to modify the responsiveness of cerebellar Purkinje cells is evaluated. It is concluded that there is no convincing evidence, at this time, to s...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/0959-4388(93)90168-x

    authors: Llinás R,Welsh JP

    更新日期:1993-12-01 00:00:00

  • Meningeal lymphatics, immunity and neuroinflammation.

    abstract::In the past five years, the surrounding of the brain, that is the meninges (singular meninx) have evolved from being a physical barrier that protects the brain parenchyma to becoming a central player for both the maintenance of normal brain function and the modulation of neurological disorders. Indeed, the meninges ar...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2019.11.010

    authors: Frederick N,Louveau A

    更新日期:2020-06-01 00:00:00

  • Multisensory integration in spatial orientation.

    abstract::Recent psychophysical studies on normal subjects, as well as brain imaging studies, have revised the concepts concerning the mechanisms underlying spatial orientation during navigation tasks. The emphasis has been put on internal models that allow the prediction of a planned trajectory and are essential in the steerin...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-4388(99)00041-0

    authors: Berthoz A,Viaud-Delmon I

    更新日期:1999-12-01 00:00:00

  • Stimulating neurons with light.

    abstract::Recent technological advances have enabled the use of different optical methods to activate neurons, including 'caged' glutamate, photoactivation of genetically engineered cascades, and direct two-photon excitation. The ability to use light as a stimulation tool provides, in principle, a non-invasive method for the te...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-4388(02)00364-1

    authors: Callaway EM,Yuste R

    更新日期:2002-10-01 00:00:00

  • Role reversal: the regulation of neuronal gene expression by microRNAs.

    abstract::In a similar fashion to transcription factors, non-coding RNAs can be essential regulators of gene expression. The largest class of non-coding RNAs is the microRNAs. These approximately 22 nt double-stranded RNA molecules can repress translation or target mRNA degradation. There has been a surge of research in the pas...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2005.08.011

    authors: Klein ME,Impey S,Goodman RH

    更新日期:2005-10-01 00:00:00

  • Myelin plasticity and behaviour-connecting the dots.

    abstract::Myelin sheaths in the vertebrate nervous system enable faster impulse propagation, while myelinating glia provide vital support to axons. Once considered a static insulator, converging evidence now suggests that myelin in the central nervous system can be dynamically regulated by neuronal activity and continues to par...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2017.09.014

    authors: Kaller MS,Lazari A,Blanco-Duque C,Sampaio-Baptista C,Johansen-Berg H

    更新日期:2017-12-01 00:00:00

  • Looking for the roots of cortical sensory computation in three-layered cortices.

    abstract::Despite considerable effort over a century and the benefit of remarkable technical advances in the past few decades, we are still far from understanding mammalian cerebral neocortex. With its six layers, modular architecture, canonical circuits, innumerable cell types, and computational complexity, isocortex remains a...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2014.09.006

    authors: Fournier J,Müller CM,Laurent G

    更新日期:2015-04-01 00:00:00

  • Determination of photoreceptor cell fate in the Drosophila retina.

    abstract::Cell-cell communication directs the development of photoreceptor cells in the Drosophila retina. A recent set of studies has provided a genetic dissection of one of these interactions, the induction of the R7 photoreceptor cell by the neighboring R8 photoreceptor cell. The results from these experiments shape our unde...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/0959-4388(94)90026-4

    authors: Krämer H,Cagan RL

    更新日期:1994-02-01 00:00:00

  • The many facets of facial interactions in mammals.

    abstract::Facial interactions are prominent behaviors in primates. Primate facial signaling, which includes the expression of emotions, mimicking of facial movements, and gaze interactions, is visually dominated. Correspondingly, in primate brains an elaborate network of face processing areas exists within visual cortex. But ot...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2011.12.003

    authors: Brecht M,Freiwald WA

    更新日期:2012-04-01 00:00:00

  • Reductions in cortical activity during priming.

    abstract::Priming is a nonconscious form of memory in which an encounter with a stimulus influences the subsequent identification, production or classification of the same or a related stimulus. Neuroimaging studies have revealed that behavioral priming is typically accompanied by reduced activity in several cortical regions. W...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2007.02.001

    authors: Schacter DL,Wig GS,Stevens WD

    更新日期:2007-04-01 00:00:00

  • Myelin-associated glycoprotein: a role in myelination and in the inhibition of axonal regeneration?

    abstract::Inhibitory molecules in CNS myelin affect axonal regeneration after injury. In the past year, myelin-associated glycoprotein (MAG), a well-characterized myelin protein, has been identified as an inhibitor of axonal regeneration. This finding, together with its established ability to promote outgrowth, defines MAG as a...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/0959-4388(95)80063-8

    authors: Filbin MT

    更新日期:1995-10-01 00:00:00

  • Signal acquisition and analysis for cortical control of neuroprosthetics.

    abstract::Work in cortically controlled neuroprosthetic systems has concentrated on decoding natural behaviors from neural activity, with the idea that if the behavior could be fully decoded it could be duplicated using an artificial system. Initial estimates from this approach suggested that a high-fidelity signal comprised of...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2004.10.013

    authors: Tillery SI,Taylor DM

    更新日期:2004-12-01 00:00:00

  • Synapse-type-specific plasticity in local circuits.

    abstract::Neuroscientists spent decades debating whether synaptic plasticity was presynaptically or postsynaptically expressed. It was eventually concluded that plasticity depends on many factors, including cell type. More recently, it has become increasingly clear that plasticity is regulated at an even finer grained level; it...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2015.08.001

    authors: Larsen RS,Sjöström PJ

    更新日期:2015-12-01 00:00:00

  • Cyclic nucleotide gated channels as regulators of CNS development and plasticity.

    abstract::Cyclic nucleotide gated (CNG) cation channels are critical for signal transduction in vertebrate visual and olfactory systems. Members of the CNG channel gene family have now been cloned from a number of species, from Caenorhabditis elegans to humans. An important advance has been the discovery that CNG channels are p...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-4388(97)80070-0

    authors: Zufall F,Shepherd GM,Barnstable CJ

    更新日期:1997-06-01 00:00:00

  • Axon and dendrite pruning in Drosophila.

    abstract::Pruning, a process by which neurons selectively remove exuberant or unnecessary processes without causing cell death, is crucial for the establishment of mature neural circuits during animal development. Yet relatively little is known about molecular and cellular mechanisms that govern neuronal pruning. Holometabolous...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2014.04.005

    authors: Yu F,Schuldiner O

    更新日期:2014-08-01 00:00:00

  • Proteins that interact with the pore-forming subunits of voltage-gated ion channels.

    abstract::Voltage-gated ion channels are composed of pore-forming subunits, as well as auxiliary subunits that modify the functions of these channels. In addition, the channels interact with other modulatory proteins in a more transient manner, although with significant effects on channel activity. Even though many second-messe...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/0959-4388(95)80040-9

    authors: Adelman JP

    更新日期:1995-06-01 00:00:00

  • How does calcium trigger neurotransmitter release?

    abstract::Recent work has established that different geometric arrangements of calcium channels are found at different presynaptic terminals, leading to a wide spectrum of calcium signals for triggering neurotransmitter release. These calcium signals are apparently transduced by synaptotagmins - calcium-binding proteins found i...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-4388(00)00214-2

    authors: Augustine GJ

    更新日期:2001-06-01 00:00:00

  • Peripheral pain mechanisms.

    abstract::Our understanding of the cellular and molecular bases of transduction of painful stimuli has burgeoned in the past year, mainly as a result of studies on isolated sensory neurones in culture. The ion channels underlying neuronal responses to noxious heat, to protons and to ATP have recently been characterized. The typ...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-4388(97)80028-1

    authors: Cesare P,McNaughton P

    更新日期:1997-08-01 00:00:00

  • Analyzing the activity of large populations of neurons: how tractable is the problem?

    abstract::Understanding how the brain performs computations requires understanding neuronal firing patterns at successive levels of processing-a daunting and seemingly intractable task. Two recent studies have made dramatic progress on this problem by showing how its dimensionality can be reduced. Using the retina as a model sy...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2007.07.002

    authors: Nirenberg SH,Victor JD

    更新日期:2007-08-01 00:00:00

  • Neural populations for maintaining body fluid balance.

    abstract::Fine balance between loss-of water and gain-of water is essential for maintaining body fluid homeostasis. The development of neural manipulation and mapping tools has opened up new avenues to dissect the neural circuits underlying body fluid regulation. Recent studies have identified several nodes in the brain that po...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2019.01.014

    authors: Ichiki T,Augustine V,Oka Y

    更新日期:2019-08-01 00:00:00

  • The perceptual logic of smell.

    abstract::Mammals have ∼1000 different olfactory receptor subtypes, each responding to a number of different odorants, and each odorant activating a number of different receptor subtypes. These molecular and anatomical underpinnings of olfaction imply a perceptual structure of very high dimensionality that relies on combinatori...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2013.12.010

    authors: Secundo L,Snitz K,Sobel N

    更新日期:2014-04-01 00:00:00

  • Neural lineage tracing in the mammalian brain.

    abstract::Delineating the lineage of neural cells that captures the progressive steps in their specification is fundamental to understanding brain development, organization, and function. Since the earliest days of embryology, lineage questions have been addressed with methods of increasing specificity, capacity, and resolution...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.conb.2017.10.013

    authors: Ma J,Shen Z,Yu YC,Shi SH

    更新日期:2018-06-01 00:00:00

  • Neural systems for behavioral activation and reward.

    abstract::The circuitry mediating the integration of reward perception and adaptive behavioral responses has been further refined. Recent developments indicate that the nucleus accumbens has a primary role in motivational circuitry, whereas afferents to the nucleus accumbens, in part, subserve distinct functions. Dopaminergic a...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-4388(99)80031-2

    authors: Kalivas PW,Nakamura M

    更新日期:1999-04-01 00:00:00

  • Temporal response properties of neurons in the auditory pathway.

    abstract::A number of laboratories have recently refined descriptions of temporal response properties, from the auditory periphery to the midbrain. At many levels of the auditory pathway, the role of inhibition in temporal coding of complex sounds is being explored. In addition, quantitative relationships between physiology and...

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/S0959-4388(99)80066-X

    authors: Carney LH

    更新日期:1999-08-01 00:00:00

  • The evolution of feeding motor patterns in vertebrates.

    abstract::Despite considerable skepticism, researchers have found that the patterns of muscle activation that control feeding behaviors of lower vertebrates have been surprisingly conserved during evolution. This tendency for conservation among taxa appears in the face of marked flexibility of motor patterns within individuals....

    journal_title:Current opinion in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/s0959-4388(02)00383-5

    authors: Wainwright PC

    更新日期:2002-12-01 00:00:00