Effect of a single-piece and a three-piece acrylic sharp-edged IOL on posterior capsule opacification.

Abstract:

BACKGROUND:To compare the intensity of posterior capsule opacification (PCO) between two intraocular lenses (IOLs) of the same optic material, but with different haptic design (1-piece vs. 3-piece). METHODS:This prospective intraindividual controlled cohort study comprised eighty eyes of 40 patients with bilateral age-related cataract. Each patient received a Polylens Y10 (Polytech, Germany) 1-piece IOL in 1 eye and a Polylens Y30 (Polytech, Germany) 3-piece IOL in the contralateral eye. The IOL type in the first operated eye was randomly assigned before patient recruitment. Digital slitlamp photographs were taken 1 year postoperatively using a standardized photographic technique for regeneratory PCO. The amount of PCO was assessed subjectively at the slitlamp and objectively using automated image-analysis software. RESULTS:The Polylens Y10 (1-piece) group showed significantly higher regeneratory and fibrotic PCO scores 1 year after surgery in subjective slitlamp evaluation, however not with objective evaluation using automated image-analysis software. Subjective PCO assessment resulted in a mean PCO score (scale = 0-10) of 1.6 in the Polylens Y10 group and 0.6 in the Polylens Y30 group at 1 year (p < 0.05). The mean automated image-analysis software PCO score was 1.5 in the Polylens Y10 group and 0.9 in the Polylens Y30 group (p = 0.6). CONCLUSION:Both investigated IOLs showed good clinical performance regarding PCO, BCVA and IOL-centration. The Polylens Y10 IOL showed slightly more regeneratory PCO than the 3-piece acrylic IOL 1 year after surgery.

journal_name

Curr Eye Res

journal_title

Current eye research

authors

Mylonas G,Prskavec M,Baradaran-Dilmaghani R,Karnik N,Buehl W,Wirtitsch M

doi

10.3109/02713683.2012.717242

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

86-90

issue

1

eissn

0271-3683

issn

1460-2202

journal_volume

38

pub_type

杂志文章,随机对照试验
  • Expression of perineuronal nets, parvalbumin and protein tyrosine phosphatase σ in the rat visual cortex during development and after BFD.

    abstract:UNLABELLED:Abstract Purpose of the Study: Protein tyrosine phosphatase σ (PTPσ) acts as a neuronal receptor for chondroitin sulfate proteoglycans (CSPGs). CSPGs have inhibitory effects on experience-dependent plasticity and usually form lattice-like cell coatings that surround the parvalbumin (PV) interneurons in the v...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2013.803287

    authors: Liu H,Xu H,Yu T,Yao J,Zhao C,Yin ZQ

    更新日期:2013-10-01 00:00:00

  • Age-Related Changes in Murine Corneal Nerves.

    abstract:PURPOSE:The aim of this study is to determine age-related morphological changes in the corneal subbasal nerve plexus (SNP) in two inbred mouse strains. MATERIALS AND METHODS:The corneal SNP was investigated by in vivo confocal laser scanning microscopy (CLSM) in 0.5-, 1-, 1.5-, and 2-year-old C57BL/6J mice and in 0.5-...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2015.1088952

    authors: Reichard M,Weiss H,Poletti E,Ruggeri A,Guthoff RF,Stachs O,Baltrusch S

    更新日期:2016-08-01 00:00:00

  • Modulation of postoperative scarring with tacrolimus and octreotide in experimental glaucoma filtration surgery.

    abstract:PURPOSE:The purposes of this study were to investigate the effects of topically administrated Tacrolimus and Octreotide on modulation of postoperative scarring in experimental glaucoma filtration surgery and to compare the antifibrotic properties of these agents with mitomycin-C (MMC). MATERIAL AND METHODS:A total of ...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2011.635404

    authors: Arslan S,Aydemir O,Güler M,Dağlı AF

    更新日期:2012-03-01 00:00:00

  • Antiproliferative drugs and human ocular fibroblasts: colorimetric vs. cell counting assays.

    abstract::Utilizing a rapid colorimetric assay that relates cell number to cytoplasmic hexosaminidase activity, we conducted drug-induced cytotoxicity experiments on human ocular fibroblasts cultured from Tenon's capsule specimens. The effects of two different agents--dimethyl sulfoxide (DMSO) or mitomycin C--on the proliferati...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689008999599

    authors: Givens KT,Lee DA,Rothschiller J,Kitada S,Larian B,Cortes A

    更新日期:1990-06-01 00:00:00

  • Dry Eye-Related Visual Blurring and Irritative Symptoms and Their Association with Depression and Anxiety in Eye Clinic Patients.

    abstract:PURPOSE:Dry eye is a common condition known to have many systemic co-morbidities. We aim to report the frequency of depression and anxiety suspects in eye clinic patients and explore the association between dry eye signs and symptoms with depression and anxiety. MATERIALS AND METHODS:Adult outpatients were recruited f...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2015.1056804

    authors: Liyue H,Chiang PP,Sung SC,Tong L

    更新日期:2016-05-01 00:00:00

  • Quantitative Analysis of Optical Coherence Tomography Angiography Features in Patients with Nonocular Behcet's Disease.

    abstract:PURPOSE:To quantitatively measure the flow, nonflow, density, and foveal avascular zone (FAZ) assessment tool parameters of optical coherence tomography angiography (OCTA) in patients with nonocular Behcet's Disease (BD), and to compare the results with those obtained in healthy controls. METHODS:FAZ parameters, flow ...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2018.1530361

    authors: Goker YS,Yılmaz S,Kızıltoprak H,Tekin K,Demir G

    更新日期:2019-02-01 00:00:00

  • Biometric Alterations of Mouse Embryonic Eye Structures Due to Short-Term Folic Acid Deficiency.

    abstract:PURPOSE:Folic acid (FA) is an essential nutrient for normal embryonic development. FA deficiency (FAD) in maternal diet increases the risk of several defects among the progeny, especially, neural tube defects. The eye begins its development from the neural tube; however, the relationship between FAD and ocular developm...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2018.1545911

    authors: Sijilmassi O,López-Alonso JM,Del Río Sevilla A,Murillo González J,Barrio Asensio MDC

    更新日期:2019-04-01 00:00:00

  • Rapamycin enhances TNF-α-induced secretion of IL-6 and IL-8 through suppressing PDCD4 degradation in orbital fibroblasts.

    abstract:PURPOSE:To investigate the effects of rapamycin on the TNF-α-induced secretion of interleukin-6 (IL-6) and IL-8 in orbital fibroblasts and its possible mechanism. MATERIALS AND METHODS:Orbital fibroblasts were obtained from patients with thyroid-associated ophthalmopathy. IL-6 and IL-8 levels were measured by enzyme-l...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2012.750368

    authors: Lee WM,Paik JS,Cho WK,Oh EH,Lee SB,Yang SW

    更新日期:2013-06-01 00:00:00

  • Ultrastructural, histochemical and biochemical studies of the melanin metabolism in pallid mouse eye.

    abstract::In an attempt to determine the factors involved in ocular pigment variation, the eyes of pallid mice (c57BL/6J-Pa/Pa), and those of littermate black mice (C57BL/6J-+/Pa) were examined ultrastructurally, histochemically, and biochemically. As controls, the eyes of black and congenic albino mice (C57BL/6J +/C2J and -C2J...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688208998376

    authors: Ito M,Hashimoto K,Organisciak DT

    更新日期:1982-01-01 00:00:00

  • Rabbits have a circadian rhythm of aqueous humor cyclic AMP.

    abstract::Rabbits have circadian rhythms of intraocular pressure (IOP) and aqueous flow. The dark phase increases of IOP and flow are associated with increased aqueous cyclic AMP. If the daily rhythm of aqueous cyclic AMP reflects changes of tissue levels of cyclic AMP which mediate one of the mechanisms which control the rhyth...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689209033491

    authors: Kiuchi Y,Gregory DS

    更新日期:1992-09-01 00:00:00

  • Human corneal epithelial cell shedding and fluorescein staining in response to silicone hydrogel lenses and contact lens disinfecting solutions.

    abstract:PURPOSE:A pilot study was conducted to evaluate human corneal epithelial cell shedding in response to wearing a silicone hydrogel contact lens/solution combination inducing corneal staining. The nature of ex vivo collected cells staining with fluorescein was also examined. METHODS:A contralateral eye study was conduct...

    journal_title:Current eye research

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/02713683.2013.841255

    authors: Gorbet M,Peterson R,McCanna D,Woods C,Jones L,Fonn D

    更新日期:2014-03-01 00:00:00

  • Role of Nitric Oxide in the Development of Cataract Formation in CdCl2-induced Hypertensive Animals.

    abstract:PURPOSE:Previously we established a strong association of systemic hypertension with cataract formation. In the present study, we investigated the role of nitric oxide (NO) in the development of cataract formation in CdCl2-induced hypertensive animals. MATERIALS AND METHODS:Hypertension was induced in male albino rats...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2018.1501490

    authors: Yadav A,Choudhary R,Bodakhe SH

    更新日期:2018-12-01 00:00:00

  • Expression of metallothionein isoforms in human chorioretinal complex.

    abstract:PURPOSE:To determine the relative expression of metallothionein isoforms and their differential induction by oxidative stress in cultured RPE cells and to localize the isoforms in the human chorioretinal complex. METHODS:Total RNA was isolated from cultured human retinal pigment epithelial cells using TRI-Reagent. An ...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.24.1.12.5426

    authors: Tate DJ,Miceli MV,Newsome DA

    更新日期:2002-01-01 00:00:00

  • Effect of topical epinephrine and timolol on ocular and optic nerve blood flow in phakic and aphakic rabbit eyes.

    abstract::The effects of 4% epinephrine bitartrate and 0.5% timolol on ocular and optic nerve blood flow were studied in phakic and aphakic rabbit eyes using a radioactive microsphere (85Sr) technique. Either epinephrine or timolol was given topically as eight drops in the hour immediately preceding blood flow measurements (one...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688409000822

    authors: Jay WM,Aziz MZ,Green K

    更新日期:1984-10-01 00:00:00

  • Pathologic changes in the retinal pigment epithelium and Bruch's membrane of fat-fed atherogenic mice.

    abstract:PURPOSE:Due to a possible link in humans between atherosclerosis, a high-fat diet, and the development of age-related retinal degenerations, we investigated retinal changes with age and diet in high-fat-fed C57BL/6 mice, a mouse model of human atherosclerosis. METHODS:We fed C57BL/6J mice either a normal chow diet or ...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:

    authors: Miceli MV,Newsome DA,Tate DJ Jr,Sarphie TG

    更新日期:2000-01-01 00:00:00

  • Choroidal Differences between Spectral and Swept-source Domain Technologies.

    abstract:PURPOSE OF THE STUDY:To assess differences in healthy eyes in volume (CV) and choroidal thicknesses (CT) across all macular Early Treatment Diabetic Retinopathy Study (ETDRS) areas measured by swept source (SS)-OCT and spectral domain (SD)-OCT with enhanced depth imaging (EDI). MATERIALS AND METHODS:One hundred and fi...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2020.1795883

    authors: Pinilla I,Sanchez-Cano A,Insa G,Bartolomé I,Perdices L,Orduna-Hospital E

    更新日期:2021-02-01 00:00:00

  • Meibomian gland dropout in patients with dry eye disease in China.

    abstract:PURPOSE:To examine the morphological changes in the meibomian glands of eyes of patients with dry eye disease using the non-contact infrared meibography system and to assess their relationship with meibomian dropout, signs, and tear-film function. METHODS:Subjects included 264 randomly selected patients (528 eyes) suf...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2014.891748

    authors: Feng Y,Gao Z,Feng K,Qu H,Hong J

    更新日期:2014-10-01 00:00:00

  • Fatty acid composition and arachidonic acid metabolism in vitreous lipids from canine and human eyes.

    abstract::About 55% of the acyl groups of dog and human vitreous are unsaturated fatty acids. The major components are oleate (18:1, n-9) and arachidonate (20:4, n-6) with moderate amounts of linoleate (18:2, n-6) and docosahexaenoate (22:6, n-3). Palmitate (16:0) and stearate (18:0) are the major saturated fatty acids. There a...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688609015113

    authors: Reddy TS,Birkle DL,Packer AJ,Dobard P,Bazan NG

    更新日期:1986-06-01 00:00:00

  • Lipid synthesis in the bovine lens.

    abstract::Lipid synthesis was investigated in bovine lens in organ culture for 9 hours using 14C acetate as a precursor. The greatest incorporation occurred in phospholipid fraction with phosphatidyl choline being the major phospholipid labeled. Considerable activity was incorporated in the free fatty acid fraction, cholesterol...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688709034889

    authors: Albers-Jackson B,Nga Do A

    更新日期:1987-09-01 00:00:00

  • Contractile effect of aqueous Pleurotus tuberregium extract on the isolated bovine iris.

    abstract:BACKGROUND:Aqueous extract of Pleurotus tuberregium (PT) has been shown to reduce intraocular pressure (IOP) but the underlying mechanism has not been explained. PURPOSE:To investigate the effect of PT on the bovine iris in vitro in comparison with acetylcholine (ACh). METHOD:Strips of the iris were mounted in 10 ml ...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2012.747615

    authors: Akinlabi GA,Asowata OE,Ozolua RI,Akpaja OO,Iyawe V

    更新日期:2013-03-01 00:00:00

  • Microcirculation in eyes after rhegmatogenous retinal detachment surgery.

    abstract:PURPOSE:To investigate the tissue blood flow in the neuroretinal rim of the optic disk and macula after rhegmatogenous retinal detachment (RRD) surgery. METHODS:Tissue blood flow in the neuroretinal rim of the optic disk and macula was measured with the Heidelberg retina flowmeter in 53 eyes of 53 patients who had und...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713680701531108

    authors: Sato EA,Shinoda K,Kimura I,Ohtake Y,Inoue M

    更新日期:2007-09-01 00:00:00

  • Refractive error, cognitive demand and nearwork-induced transient myopia.

    abstract:PURPOSE:Whereas many previous studies have identified the association between sustained near work and myopia, few have assessed the influence of concomitant levels of cognitive effort. This study investigates the effect of cognitive effort on near-work induced transient myopia (NITM). METHODS:Subjects comprised of six...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.27.6.363.18190

    authors: Wolffsohn JS,Gilmartin B,Thomas R,Mallen EA

    更新日期:2003-12-01 00:00:00

  • The effect of elevated extracellular glucose on migration, adhesion and proliferation of SV40 transformed human corneal epithelial cells.

    abstract:PURPOSE:To examine the effect of elevated extracellular glucose, thus simulating diabetes, on migration, adhesion and proliferation of SV40 transformed human corneal epithelial (HCE) cells. METHODS:HCE cells were maintained in serum supplemented media containing 5 mM, 17.5 mM or 38 mM D-glucose. Cell migration was det...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.17.9.924.5133

    authors: McDermott AM,Kern TS,Murphy CJ

    更新日期:1998-09-01 00:00:00

  • The structure of the lens epithelium and its basement membrane in the diabetic state.

    abstract::The basement membrane of the crystalline lens of the diabetic rat was found to have a similar elasticity modulus at high stress to that of normal membrane. However, at low stress and extension Young's modulus of elasticity was 0.36 (Mean) +/- 0.15 (SD) X 10(6) Nm-2 and about 30 per cent lower than that of normal membr...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688108998358

    authors: Hayes BP,Fisher RF

    更新日期:1981-01-01 00:00:00

  • Selenite and Ca2+ homeostasis in the rat lens: effect on Ca-ATPase and passive Ca2+ transport.

    abstract::Calcium permeability was significantly increased in lenses from rats 36 h following a single injection of a cataractogenic dose of sodium selenite (30 nmol/g body weight) and this permeability returned to control values by 72 h post-injection (PI). The greater Ca2+ permeability could be partially reversed by incubatin...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689308999466

    authors: Wang Z,Bunce GE,Hess JL

    更新日期:1993-03-01 00:00:00

  • Angiogenic profile of uveal melanoma.

    abstract::Uveal melanoma develops in one of the most capillary-rich tissues of the body and is disseminated hematogenously. Knowledge of the nature and the spatiotemporal expression of angiogenic factors in uveal melanoma is essential to the development of new treatment strategies, especially with regard to improving survival. ...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713680600865052

    authors: Notting IC,Missotten GS,Sijmons B,Boonman ZF,Keunen JE,van der Pluijm G

    更新日期:2006-09-01 00:00:00

  • Ciliary neurotrophic factor induces glial fibrillary acidic protein in retinal Müller cells through the JAK/STAT signal transduction pathway.

    abstract:PURPOSE:Intravitreal injection of ciliary neurotrophic factor (CNTF) is known to induce glial intermediate filament protein (GFAP) expression in retinal Müller cells. Because CNTF binding can activate multiple signaling kinases, we have examined the involvement of JAK/STAT pathway in GFAP induction in Müller cells. ME...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.24.4.305.8408

    authors: Wang Y,Smith SB,Ogilvie JM,McCool DJ,Sarthy V

    更新日期:2002-04-01 00:00:00

  • Multiple, spatially distinct T cell epitopes within a pathogenic 123 residue cyanogen bromide peptide of bovine retinal s-antigen.

    abstract::We have examined the T cell specificity of a Lewis rat T cell line (R208) specific for a pathogenic, 123 residue cyanogen bromide produced peptide of bovine S-antigen by using two independent sets of overlapping synthetic peptides representing the entire length of the 123 residue fragment. S-antigen, a 48 kDa immunopa...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689008999429

    authors: Fling SP,Gregerson DS,Obritsch WF,Boyce-Jacino M,Merryman CF,Donoso LA

    更新日期:1990-01-01 00:00:00

  • The efficacy of piperacillin/tazobactam in experimental Pseudomonas aeruginosa endophthalmitis: a histopathological and microbiological evaluation.

    abstract:PURPOSE:To investigate the efficacy of intravitreal piperacillin/tazobactam (250 microg/0.1 ml) in the treatment of experimental Pseudomonas aeruginosa endophthalmitis in rabbits. MATERIALS AND METHODS:Twenty New Zealand White albino rabbits were used in this study. The rabbits were divided into two groups (10 rabbits...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713680490894180

    authors: Ozkiris A,Evereklioglu C,Esel D,Akgün H,Göktas S,Erkiliç K

    更新日期:2005-01-01 00:00:00

  • Age does not affect contractile responses of the isolated rhesus monkey ciliary muscle to muscarinic agonists.

    abstract::In primates, ciliary muscle contraction causes accommodation and facilitates aqueous outflow. In living rhesus monkeys, accommodative, outflow facility, and ciliary muscle movement responses to cholinergic agonists all decline with age. We developed an apparatus to determine in vitro whether the latter is related to i...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689309024623

    authors: Poyer JF,Kaufman PL,Flügel C

    更新日期:1993-05-01 00:00:00