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Developing and evaluating prediction models in rehabilitation populations.

Abstract：

:This article presents a 3-part framework for developing and evaluating prediction models in rehabilitation populations. First, a process for developing and refining prognostic research questions and the scientific approach to prediction models is presented. Primary components of the scientific approach include the study design and sampling of patients, outcome measurement, selecting predictor variable(s), minimizing methodologic sources of bias, assuring a sufficient sample size for statistical power, and selecting an appropriate statistical model. Examples focus on prediction modeling using samples of rehabilitation patients. Second, a brief overview for statistically building and validating multivariable prediction models is provided, which includes the following 7 steps: data inspection, coding of predictors, model specification, model estimation, model performance, model validation, and model presentation. Third, we propose a set of primary considerations for evaluating prediction model studies using specific quality indicators as criteria to help stakeholders evaluate the quality of a prediction model study. Lastly, we offer perspectives on the future development and use of rehabilitation prediction models.

journal_name

Arch Phys Med Rehabil

journal_title

Archives of physical medicine and rehabilitation

authors

Seel RT,Steyerberg EW,Malec JF,Sherer M,Macciocchi SN

doi

10.1016/j.apmr.2012.04.021

subject

Has Abstract

pub_date

2012-08-01 00:00:00

pages

S138-53

issue

8 Suppl

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(12)00317-6

journal_volume

93

pub_type

杂志文章

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