Abstract：
:Plastic bronchitis (PB) is a poorly understood disease that can complicate any underlying pulmonary disease. However, it appears to most often occur in patients with surgically palliated congenital heart disease, particularly after the Fontan procedure. Few data exist about the prevalence and etiology of PB in this population. In an effort to establish data about prevalence, we conducted a retrospective study of an existing Fontan surgery database (n = 654) comprised of data, including sex, age at date of surgery, alive/dead status, New York Heart Association classification at last follow-up, right-ventricular end-diastolic pressure and pulmonary artery pressure before Fontan surgery, and the presence of a Fontan fenestration. An initial medical record review of 173 patients in the database who were followed at the University of Michigan identified seven patients with PB resulting in an estimated prevalence of 4 %. Subsequently, 14 % of 211 surveyed patients reported that they presently expectorate mucus or fibrin plugs (casts). Demographic and clinical variables did not differ between patients with or without possible PB. Collectively, these findings suggest that Fontan patients presently with PB may range from 4 to 14 %, indicating potential under-diagnosis of the disease. There were no remarkable physical or hemodynamic indicators that differentiated patients with or without possible PB. These data also highlight the need for more elaborate, prospective studies to improve our understanding of PB pathogenesis so that more definitive diagnostic criteria for this devastating disease can be established and its prevalence more accurately determined.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Caruthers RL,Kempa M,Loo A,Gulbransen E,Kelly E,Erickson SR,Hirsch JC,Schumacher KR,Stringer KAdoi
10.1007/s00246-012-0430-5subject
Has Abstractpub_date
2013-02-01 00:00:00pages
256-61issue
2eissn
0172-0643issn
1432-1971journal_volume
34pub_type
杂志文章abstract：:Transcatheter pulmonary valve implantation in the setting of right ventricle-to-pulmonary artery conduit dysfunction is a relatively new procedure with encouraging early and midterm results. Malpositioning of the valve during implantation is a potentially serious complication. This report describes a case in which val...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0224-9
更新日期：2012-06-01 00:00:00
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journal_title：Pediatric cardiology
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journal_title：Pediatric cardiology
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journal_title：Pediatric cardiology
pub_type： 杂志文章
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journal_title：Pediatric cardiology
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journal_title：Pediatric cardiology
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journal_title：Pediatric cardiology
pub_type： 杂志文章
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0649-9
更新日期：2013-08-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2004-01-01 00:00:00
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pub_type： 杂志文章,已发布勘误
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pub_type： 杂志文章,随机对照试验
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journal_title：Pediatric cardiology
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更新日期：1986-01-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
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journal_title：Pediatric cardiology
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journal_title：Pediatric cardiology
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更新日期：1982-01-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
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更新日期：1998-11-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章,多中心研究
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更新日期：2014-12-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
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更新日期：1993-07-01 00:00:00
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更新日期：2013-01-01 00:00:00
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journal_title：Pediatric cardiology
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更新日期：1988-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2019-03-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
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pub_type： 杂志文章,meta分析,评审
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更新日期：2017-06-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02427034
更新日期：1982-01-01 00:00:00
