Multilocular cystic renal cell carcinoma with focus on clinical and pathobiological aspects.

abstract：:Cell secretion is an important physiological process that ensures smooth metabolic activities, tissue repair and growth and immunological functions in the body. It occurs when the intracellular secretory materials are released to the exterior; these may be in the form of lipids, protein or mucous and may travel throug...

journal_title：Histology and histopathology

authors： Gesase AP,Satoh Y

更新日期：2003-04-01 00:00:00

abstract：:An electron microscopic study of the myoepithelial cells in the chicken Harderian gland provides evidence that these cells can be transformed into myofibroblasts. After the application of a Brucella ovis suspension in sterile saline onto the eyeball, every 5 minutes for half an hour, myoepithelial cells gradually deve...

journal_title：Histology and histopathology

authors： del Cacho E,Gallego M,Felices C,Bascuas JA

更新日期：1991-07-01 00:00:00

abstract：:The corneal structure of three deep-sea species of teleosts (Gadiformes, Teleostei) from different depths (250-4000 m) and photic zones are examined at the level of the light and electron microscopes. Each species shows a similar but complex arrangement of layers with a cornea split into dermal and scleral components....

journal_title：Histology and histopathology

authors： Collin SP,Collin HB

更新日期：1998-04-01 00:00:00

abstract：:We examined the relationship between the incidence of ultrastructural changes in the alveolar septum and the extravascular lung water content. Pulmonary edema was induced in 18 mongrel dogs by either dextran (n = 12) or alloxan (n = 6) administration. Six other dogs served as controls. Extravascular lung water content...

journal_title：Histology and histopathology

authors： Oda H,Arakawa M,Kambara K,Nakahara K,Segawa T,Ando F,Kawada T,Hirakawa S,Shoumura S,Isono H

更新日期：1993-01-01 00:00:00

abstract：:The S100 gene family, which is composed of at least 24 members carrying the Ca2+ binding EF-hand motif, has been implicated in both intracellular and extracellular functions, including enzyme activities, immune responses, cytoskeleton dynamics, Ca2+ homeostasis, cell growth and cell differentiation. Altered S100 prote...

journal_title：Histology and histopathology

authors： Yao R,Davidson DD,Lopez-Beltran A,MacLennan GT,Montironi R,Cheng L

更新日期：2007-09-01 00:00:00

abstract：AIMS:Gastric hyperplastic polyps (GHPs) are the most common polypoid lesion of the stomach, and their malignant potential has been demonstrated. In the present study, we evaluated the mucin phenotypes of GHPs and investigated the relationships among mucin phenotypes and clinical-pathological factors, proliferative acti...

journal_title：Histology and histopathology

authors： Li J,Wu LH,Shi Y,Li HM,Song MY,Jiao YF

更新日期：2014-03-01 00:00:00

abstract：:Actin microfilaments and microtubules are important cytoskeletal proteins that regulate endothelial repair through alterations in cell shape and through regulation of cell migration following wounding of the endothelium. Upstream pathways have been identified in the regulation of actin and microtubule organization, es...

journal_title：Histology and histopathology

authors： Lee JS,Gotlieb AI

更新日期：2003-07-01 00:00:00

abstract：:Although traditionally little attention has been paid to the interplay between neurotrophins and the cell cycle, a number of recent findings suggest an important role for these growth factors in the regulation of this aspect of the cellular physiology. In this article, we review the evidence from a number of studies t...

journal_title：Histology and histopathology

authors： López-Sánchez N,Frade JM

更新日期：2002-10-01 00:00:00

abstract：AIMS:The expression patterns of TGFB signaling proteins, such as TGFB1/2, TGFBR1(ALK5), TGFBR2, SMAD1/2/3, SMAD2/3, SMAD4, SMAD7, and of downstream targets of TGFB signaling, CDKN1A (p21CIP1), CDKN1B (p27KIP1), MYC, CDC25A, TP53, and RELA (p65NF-kB) were investigated in gastric carcinomas and other gastric lesions. ME...

journal_title：Histology and histopathology

authors： Kim SH,Lee SH,Choi YL,Wang LH,Park CK,Shin YK

更新日期：2008-12-01 00:00:00

abstract：:Terminal dendrites of cone horizontal cells (HCs) in teleost retinas show numerous spine-like protrusions named spinules, which are invaginated into the cone pedicles during light-adaptation, but retracted during dark-adaptation. Somata of HC show nematosomes whose size decreases as the number of spinules increases. M...

journal_title：Histology and histopathology

authors： García M,Grzywacz NM,De Juan J

更新日期：2002-01-01 00:00:00

abstract：:Morphological and biochemical alterations have been described in neurons of the aged human brain. However, the cell death process associated with neuronal senescence remains to be elucidated. Apoptosis and autophagic degeneration, two modes of programmed cell death described in embryogenesis and tissue renewal in adul...

journal_title：Histology and histopathology

authors： Anglade P,Vyas S,Hirsch EC,Agid Y

更新日期：1997-07-01 00:00:00

abstract：:Aluminium (Al) is a neurotoxic metal and Al exposure may be a factor in the aetiology of various neurodegenerative diseases such as Alzheimer's disease (AD). The major pathohistological findings in the AD brain are the presence of neuritic plaques containing beta-amyloid (Abeta) which may interfere with neuronal commu...

journal_title：Histology and histopathology

authors： Rodella LF,Ricci F,Borsani E,Stacchiotti A,Foglio E,Favero G,Rezzani R,Mariani C,Bianchi R

更新日期：2008-04-01 00:00:00

abstract：:In mouse embryos, the expression of Blimp1 has recently revealed a population of allocated primordial germ cell precursors 24 hours earlier than previously thought. Those 'blimped' precursors have been shown to give rise, by mitotic division, to germ cells only and no other cell lineages. Here, we try to understand th...

journal_title：Histology and histopathology

authors： Chuva de Sousa Lopes SM,Roelen BA

更新日期：2008-12-01 00:00:00

abstract：:The antifibrotic activity of Liver Growth Factor (LGF), a liver mitogen, was previously demonstrated in several models of rat liver fibrosis and even in extrahepatic sites, such as carotid artery in hypertensive rats and rat CdCl2-induced lung fibrosis. In the present study, we have attempted to examine in depth its m...

journal_title：Histology and histopathology

authors： Díaz-Gil JJ,García-Monzón C,Rúa C,Martín-Sanz P,Cereceda RM,Miquilena-Colina ME,Machín C,Fernández-Martínez A,García-Cañero R

更新日期：2009-04-01 00:00:00

abstract：:The three-dimensional structure of the pancreatic ductular system (from the intercalated duct to the intercellular secretory canaliculus) is controversial and unclear. The aim of this study is to reveal the three-dimensional structure of the pancreatic ductular sysytem at the onset of pancreatitis. One day following r...

journal_title：Histology and histopathology

authors： Endo H,Ashizawa N,Niigaki M,Hamamoto N,Niigaki M,Kaji T,Katsube T,Watanabe M,Naora H,Otani H,Kinoshita Y

更新日期：2002-01-01 00:00:00

abstract：:Glucose uptake and metabolism are essential for proliferation and survival of cells, and are supposed to be enhanced in actively proliferating cell systems such as embryonic and cancer tissues. Glucose uptake is usually carried out through glucose transporters. In the developing fetal lung, metabolism of glucose is th...

journal_title：Histology and histopathology

authors： Ito T,Noguchi Y,Udaka N,Kitamura H,Satoh S

更新日期：1999-07-01 00:00:00

abstract：:In the lungs, neuronal M2 muscarinic receptors limit the release of acetylcholine from postganglionic cholinergic nerves. However, these receptors are not functional under certain circumstances in animal models of hyperreactivity such as occurs after exposure of sensitised animals to an allergen or during a respirator...

journal_title：Histology and histopathology

authors： Costello RW,Jacoby DB,Gleich GJ,Fryer AD

更新日期：2000-07-01 00:00:00

abstract：:Neutrophil extracellular traps (NETs) are innate immune systems against invading pathogens. NETs are characterized as released DNA mixed with cytoplasmic antimicrobial proteins such as myeloperoxidase, proteinase3 and neutrophil elastase. While NETs are thought to have an important role in host defense, recent work ha...

journal_title：Histology and histopathology

authors： Nakazawa D,Kumar S,Desai J,Anders HJ

更新日期：2017-03-01 00:00:00

abstract：:In Duchenne muscular dystrophy (DMD), the progressive loss of muscle and its ability to function is associated with significant fibrosis, representing the major disease complication in patients. Halofuginone, a halogenated analog of the naturally occurring febrifugine, has been shown to prevent fibrosis in various ani...

journal_title：Histology and histopathology

authors： Wellner G,Mordechay S,Evans P,Genin O,Pines M,Halevy O

更新日期：2019-07-01 00:00:00

abstract：:Immunohistochemistry of the terminal complement complex (C5b-9) and fibronectin (FN) is useful to detect myocardial ischemia preceding necrosis in the postmortem diagnosis of sudden cardiac death. The present immunohistochemical study examined connexin43 (Cx43) and zonula occludens-1 (ZO-1) as markers of early myocard...

journal_title：Histology and histopathology

authors： Kawamoto O,Michiue T,Ishikawa T,Maeda H

更新日期：2014-06-01 00:00:00

abstract：:Chaperone-mediated autophagy (CMA), a selective form of autophagy, where cellular proteins with KFERQ-like motif are targeted to the lysosome for degradation, is necessary to maintain cellular homeostasis. The role of CMA in neurodegenerative diseases has been extensively studied in the past decades, with defects in t...

journal_title：Histology and histopathology

authors： Hou T,Fan Y,Dan W,Liu B,Wang Z,Zeng J,Li L

更新日期：2020-07-01 00:00:00

abstract：:Gp96 is the endoplasmic reticulum (ER)-resident molecular chaperone, which is involved in the correction of unfolded proteins, in the activation of proteasome-dependent ER-associated degradation of the misfolded proteins, and in activation of the protein translation that modulates polypeptide traffic into the ER. Furt...

journal_title：Histology and histopathology

authors： Jakovac H,Grebic D,Barac-Latas V,Mrakovcic I,Radosevic-Stasic B

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The Shwachman-Bodian-Diamond syndrome (SBDS) protein is a member of a highly conserved family which influences RNA activation and is associated with pancreatic, skeletal and bone marrow deficiencies, as well as hematological malignancies. METHODS:In this study, the expression and localization of SBDS were i...

journal_title：Histology and histopathology

authors： Kayed H,Bekasi S,Keleg S,Welsch T,Esposito I,Shimamura A,Michalski CW,Friess H,Kleeff J

更新日期：2008-07-01 00:00:00

abstract：:Tumorigenesis correlates with hypermethylation of tumor suppressors and hypomethylation of oncogenes. DNA methyltransferases (DNMTs) catalyze DNA methylation, and mutations and aberrant expression in DNMT genes are found in multiple human tumors. The discovery of the DNA demethylation function of TET proteins has open...

journal_title：Histology and histopathology

authors： Wu YC,Ling ZQ

更新日期：2014-08-01 00:00:00

abstract：:Membranous glomerulonephritis caused in Barbus graellsi by myxosporidian infections have been studied by electron microscopy and immunoelectron microscopy techniques. This study indicates that Myxosporidian infection produces a chronic severe aggression. Spores reach the spleen, the kidney and the liver, where they ar...

journal_title：Histology and histopathology

authors： Peribañez MA,del Cacho E,Castillo JA,Arnal MC

更新日期：1993-10-01 00:00:00

abstract：:PML is a tumour suppressor inactivated in Acute Promyelocytic Leukaemia (APL). PML is the essential component of a subnuclear structure called the PML nuclear body (PML-NB), which is disrupted in APL. By targeting different cellular proteins to this structure, PML can either hamper or potentiate their functions. The P...

journal_title：Histology and histopathology

authors： Salomoni P,Bellodi C

更新日期：2007-08-01 00:00:00

abstract：:Processing adult human trabecular bone to obtain tissue sections suitable for research or diagnostic purposes has always been challenging, particularly in the preparation of adult bone specimens for advanced immunohistochemistry applications. In contrast to the majority of soft tissues, decalcified bone samples perfor...

journal_title：Histology and histopathology

authors： Maly IP,Rahner C,Nowakowski AM,Müller-Gerbl M

更新日期：2013-12-01 00:00:00

abstract：:The terms construct or tissue equivalent refer to neotissue produced by tissue engineering techniques. The elements forming the construct are scaffolds on which cells are "recreated" to form an engineered-tissue sensitive to certain cell signals. The ability of the cells to expand and differentiate on the scaffold is ...

journal_title：Histology and histopathology

authors： Buján J,Pascual G,Corrales C,Gómez-Gil V,Rodríguez M,Bellón JM

更新日期：2005-07-01 00:00:00

abstract：:Macrophages play important roles in host defense mechanisms. In the brain, besides microglial cells, meningeal macrophages are present. However, the pathobiological characteristics of meningeal macrophages in rats remain to be investigated. In normal meninx, immunohistochemically, macrophages reacting to CD163 (macrop...

journal_title：Histology and histopathology

authors： Yamate J,Ishimine S,Izawa T,Kumagai D,Kuwamura M

更新日期：2009-01-01 00:00:00

abstract：:A rat IgG2a monoclonal antibody against a stage-specific fetal glycoprotein with a molecular mass of 68 kDa (FGP68) was produced and applied to paraffin sections. This monoclonal antibody was used to compare the expression of FGP68 with that of both alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA) in 75 hepa...

journal_title：Histology and histopathology

authors： Kato M,Shinozawa T,Kato S,Terada T

更新日期：2004-07-01 00:00:00