Abstract：
BACKGROUND:During the induction of anesthesia, patients are at risk of aspiration while awaiting full muscle relaxation. Magnesium has been shown to have synergistic effects with neuromuscular blocking drugs. We tested if magnesium, as an adjunct, increases the speed of onset of muscle relaxation, thereby decreasing the risk of aspiration. METHODS:Eighty-eight American Society of Anesthesiologists (ASA) physical status 1 or 2 patients were randomly assigned to three groups. Group Mg-0 received 100 mL of normal saline, whereas groups Mg-25 and Mg-50 received magnesium sulfate at doses of 25 and 50 mg/kg, respectively. Anesthesia was induced with thiopental 5 mg/kg and cisatracurium 0.15 mg/kg. A peripheral nerve stimulator and single-twitch test was performed on the ulnar nerve until the twitch responses to stimulation had disappeared, and the times were recorded. Then the patients were intubated and anesthesia was maintained with 100 μg/kg/min of propofol. The intensity of blockade was measured at regular time intervals with the post-tetanic count test. RESULTS:The mean times to muscle relaxation in groups Mg-0, Mg-25, and Mg-50 were 226, 209, and 188 s, respectively (P = 0.047). The intensity of the block increased with the dose of magnesium, and remained highest in group Mg-50 at all times measured (P < 0.05). The speed of onset and the intensity of muscle relaxation increased as higher doses of magnesium were used. CONCLUSION:The increased speed of onset of muscle relaxation produced by magnesium is not substantial enough to justify its use in combination with cisatracurium in rapid sequence induction.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Ghodraty MR,Saif AA,Kholdebarin AR,Rokhtabnak F,Pournajafian AR,Nikzad-Jamnani AR,Shah A,Nader NDdoi
10.1007/s00540-012-1439-xsubject
Has Abstractpub_date
2012-12-01 00:00:00pages
858-63issue
6eissn
0913-8668issn
1438-8359journal_volume
26pub_type
杂志文章,随机对照试验abstract：:Airway management in patients of faciomaxillary injury is of great concern to the anesthesiologist. Bag and mask ventilation and orotracheal intubation may be difficult with these patients. Recently, a middle aged, obese female presented in the emergency department after sustaining a blast injury, with laceration of t...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-010-1091-2
更新日期：2011-04-01 00:00:00
abstract：:The direct inotropic action of seven local anesthetics: procaine, mapivacaine, lidocaine, tetracaine, chloroprocaine, bupivacaine and etidocaine were compared in isolated cat papillary muscles. All of the local anesthetics produced a dose-related depression of maximal velocity of shortening (Vmax), maximal developed f...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s0054000040001
更新日期：1990-01-01 00:00:00
abstract：PURPOSE:Multimodal analgesia increases the chance of successful discharge and pain control after surgery, and pregabalin is being promoted as an effective analgesic, based on placebo-controlled studies. We investigated whether adding pregabalin improved pain control and reduced opioid requests when it was added to a mu...
journal_title：Journal of anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00540-012-1447-x
更新日期：2012-12-01 00:00:00
abstract：PURPOSE:The newly introduced erector spinae plane block (ESPB) has given anesthesiologists an alternative regional anesthetic technique for thoracic analgesia. Although ESPB and retrolaminar block (RLB) have similar puncture sites, no clinical study comparing ESPB and RLB has been reported. The aim of this study was to...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-020-02855-y
更新日期：2021-02-01 00:00:00
abstract：PURPOSE:To identify whether the presence of preoperative depression in patients with diabetes mellitus is a risk factor for postoperative cognitive dysfunction after coronary artery bypass graft (CABG) surgery. METHODS:Data from 90 patients with diabetes mellitus undergoing elective CABG were analyzed. Hemodynamic dat...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-010-1072-5
更新日期：2011-02-01 00:00:00
abstract：:Adenosine triphosphate as well as sodium nitroprusside has been used for hypotensive anesthesia. The purpose of this study was to examine the possibility that two hypotensive drugs may exert different effects on venous capacitance during controlled hypotension. In rats anesthetized with ketamine, mean arterial pressur...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s0054070010143
更新日期：1987-09-01 00:00:00
abstract：:Admission on the day of surgery for elective cardiac and non-cardiac surgery has been established as a prevalent, critical practice. This approach realizes medical, logistical, psychological and fiscal benefits, and its success is predicated on an effective outpatient pre-operative evaluation. The establishment of a h...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-016-2139-8
更新日期：2016-06-01 00:00:00
abstract：:Laryngeal mask airway (LMA) insertion was tried in 120 pediatric cases, from 2 months to 12 years of age. Initial indications for LMA were the same as for a face mask, except for two additional conditions; anticipation of difficulty with intubation and difficulty in management by a face mask. Size 2 LMA was used in th...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s0054010050160
更新日期：1991-04-01 00:00:00
abstract：:A 72-year-old woman presented pulmonary embolism. Continuous intravenous administration of heparin was controlled with values of activated clotting time targeted from 150 to 180 s. On the sixth intensive care unit (ICU) day, a central vein (CV) catheter was inserted through the right axillary vein. On the ninth ICU da...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-010-0894-5
更新日期：2010-04-01 00:00:00
abstract：:To avoid the risk of R-on-T incident and the unnecessary decrease of cardiac output, we devised an algorithm consisting of six steps for choosing the most appropriate intraoperative pacemaker (PM) mode, which is modified from Heart Rhythm Society and the American Society of Anesthesiologists expert consensus statement...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-020-02878-5
更新日期：2021-02-01 00:00:00
abstract：PURPOSE:Flexible fiber-optic bronchoscope-guided orotracheal intubation is a valuable technique with demonstrated benefits in the management of difficult airways. Despite its popularity with anesthesia providers, the technique is not fail-safe and airway-related complications secondary to failed intubation attempts rem...
journal_title：Journal of anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00540-014-1920-9
更新日期：2015-04-01 00:00:00
abstract：PURPOSE:Stroke volume variation (SVV) is affected by many factors. Although elevated intra-abdominal pressure and a pneumoperitoneum have been shown to increase SVV in animals, a recent human study showed that SVV did not change as a pneumoperitoneum was established. However, we considered the results of this study que...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-014-1963-y
更新日期：2015-08-01 00:00:00
abstract：:The direct effects of nitrous oxide on left ventricular contractility and myocardial oxygen consumption (MVO2) in the ischemic isolated rat heart were studied. The rat heart was isolated and perfused by a Langendorf technique. The aortic stump was cannulated and the heart was perfused with Kumpeis solution bubbled wit...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/BF02514658
更新日期：1994-09-01 00:00:00
abstract：PURPOSE:The incidence of postoperative pharyngolaryngeal complications after laryngeal mask airway (LMA) insertion can be as high as 50%. Over-inflation of the LMA cuff may be a causal factor. We conducted a single-centre parallel group randomised trial to determine whether maintaining LMA-ProSeal intra-cuff pressures ...
journal_title：Journal of anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00540-014-1811-0
更新日期：2014-10-01 00:00:00
abstract：:In the original publication of the article, the acknowledgment section was not included and provided in this correction. ...
journal_title：Journal of anesthesia
pub_type： 已发布勘误
doi：10.1007/s00540-020-02774-y
更新日期：2020-08-01 00:00:00
abstract：PURPOSE:We hypothesized that, after axillary block, positioning the patient in a lateral position with the injected side down and simultaneously in a 20° Trendelenburg position will increase the success rate and quality of the block. METHODS:Fifty patients with chronic renal failure (ASA 2-3) scheduled for arterioveno...
journal_title：Journal of anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00540-013-1766-6
更新日期：2014-08-01 00:00:00
abstract：:We measured plasma epinephrine and norepinephrine concentrations in a rabbit model simulating subarachnoid hemorrhage (SAH), following the injection of prostaglandin F(2alpha) (PGF(2alpha)) into the basal cistern. In this model, plasma epinephrine values increased significantly (to 4.2-fold those before injection), su...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s0054020060161
更新日期：1992-04-01 00:00:00
abstract：BACKGROUND:Postanesthetic shivering can be triggered by surgical stress and several aspects of anesthetic management and is frequently preceded by a decrease in peripheral blood flow due to thermoregulatory vasoconstriction. As perfusion index correlates with peripheral blood flow, we examined whether perioperative per...
journal_title：Journal of anesthesia
pub_type： 临床试验,杂志文章
doi：10.1007/s00540-013-1658-9
更新日期：2014-02-01 00:00:00
abstract：:Cerebral injury following cardiac surgery continues to be a significant source of morbidity and mortality after cardiac surgery. A spectrum of injuries ranging from subtle neurocognitive dysfunction to fatal strokes are caused by a complex series of multifactorial mechanisms. Protecting the brain from these injuries h...
journal_title：Journal of anesthesia
pub_type： 杂志文章,评审
doi：10.1007/s00540-007-0514-1
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:Direct hemoperfusion (DHP) with polymixin B-immobilized fiber (PMX) has been reported to be effective for patients with septic shock. The aim of this study was to clarify the mechanism of PMX-DHP effect on septic shock. METHODS:The following parameters were measured in septic shock patients who were treated wi...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-005-0366-5
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:The sedative effects of pregabalin during perioperative period have not been sufficiently characterized. The aim of this study was to verify the sedative effects of premedication with pregabalin on intravenous sedation (IVS) using propofol and also to assess the influences of this agent on circulation, respirat...
journal_title：Journal of anesthesia
pub_type： 临床试验,杂志文章
doi：10.1007/s00540-017-2366-7
更新日期：2017-08-01 00:00:00
abstract：:Amrinone, a phosphodiesterase inhibitor, is a non-glycosidic noncatecholamine with both vasodilator and positive inotropic effects. We were interested in assessing the effect of amrinone on postischemic cardiac performance in the isolated heart-lung preparation. Twenty-four male Wistar-ST rats were used. They were ran...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/BF02483394
更新日期：1996-12-01 00:00:00
abstract：:In this case series study, we prospectively examined whether it might be possible to check the effect of spinal anesthesia (SA), based on the disappearance of lower extremity reflexes and spasticity, in patients with spinal cord injury (SCI), in whom the effect cannot be confirmed by the pinprick test or by using the ...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-012-1429-z
更新日期：2012-12-01 00:00:00
abstract：:Levobupivacaine has been developed as a safer alternative to bupivacaine because of its reduced systemic toxicity. However, the effect of directly delivering levobupivacaine into tracheal smooth muscle has not been adequately explored. We performed this study to determine the in vitro effects of levobupivacaine on iso...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-015-2026-8
更新日期：2015-10-01 00:00:00
abstract：PURPOSE:Although an α-adrenoceptor has been suggested to be involved in the mechanism of asthma, the effect of α1-agonist on the airway is still unclear. In this study we evaluated the effect of phenylephrine on the airway with a direct visualization method using a superfine fiberoptic bronchoscope (SFB). METHODS:Seve...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/BF02480091
更新日期：1998-09-01 00:00:00
abstract：PURPOSE:The study was planned to compare the sensitivity of a twitch neuromuscular monitoring test, the train-of-four (TOF), with a tetanic test, double-burst stimulation (DBS), during a subclinical dose of vecuronium. METHODS:Twenty consenting. ASA I patients (16 to 65 years of age) of both sexes were studied. The ul...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/BF02480738
更新日期：1997-12-01 00:00:00
abstract：PURPOSE:Transthoracic esophagectomy is an invasive surgery, and the excessive surgical stress produces inflammatory cytokines, which provoke acute respiratory distress syndrome (ARDS). Sivelestat sodium hydrate-a selective neutrophil elastase inhibitor-is used to treat or prevent ARDS in patients undergoing esophagecto...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-018-2602-9
更新日期：2019-04-01 00:00:00
abstract：:With the aim to optimize surgical safety, the World Health Organization (WHO) introduced the Surgical Safety Checklist (SSCL) in 2008. The SSCL has been piloted in many countries worldwide and shown to improve both safety attitudes within surgical teams and patient outcomes. In the study reported here we investigated ...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-013-1737-y
更新日期：2014-06-01 00:00:00
abstract：PURPOSE:We hypothesized anterograde amnesia could be predicted by the bispectral index (BIS) during epidural puncture in patients premedicated with intramuscular midazolam. METHODS:We investigated 64 consecutive patients undergoing gynecological laparotomy under general anesthesia combined with epidural anesthesia. Mi...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-009-0748-1
更新日期：2009-01-01 00:00:00
abstract：:We have performed a systematic literature review and a meta-analysis investigating the effect of beta-adrenergic antagonist on perioperative pain in randomized clinical trials (RCTs). The search included the CENTRAL, CINAHL, EMBASE, and MEDLINE databases (from inception to 10 February 2015). From the retrieved full te...
journal_title：Journal of anesthesia
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00540-015-2041-9
更新日期：2015-12-01 00:00:00
