Abstract：
:High-level occupational radon exposure is an established risk factor for lung cancer. We assessed the long-term association between residential radon and lung cancer risk using a prospective Danish cohort using 57,053 persons recruited during 1993-1997. We followed each cohort member for cancer occurrence until 27 June 2006, identifying 589 lung cancer cases. We traced residential addresses from 1 January 1971 until 27 June 2006 and calculated radon at each of these addresses using information from central databases regarding geology and house construction. Cox proportional hazards models were used to estimate incidence rate ratios (IRR) and 95% confidence intervals (CI) for lung cancer risk associated with residential radon exposure with and without adjustment for sex, smoking variables, education, socio-economic status, occupation, body mass index, air pollution and consumption of fruit and alcohol. Potential effect modification by sex, traffic-related air pollution and environmental tobacco smoke was assessed. Median estimated radon was 35.8 Bq/m(3). The adjusted IRR for lung cancer was 1.04 (95% CI: 0.69-1.56) in association with a 100 Bq/m(3) higher radon concentration and 1.67 (95% CI: 0.69-4.04) among non-smokers. We found no evidence of effect modification. We find a positive association between radon and lung cancer risk consistent with previous studies but the role of chance cannot be excluded as these associations were not statistically significant. Our results provide valuable information at the low-level radon dose range.
journal_name
Environ Resjournal_title
Environmental researchauthors
Bräuner EV,Andersen CE,Sørensen M,Andersen ZJ,Gravesen P,Ulbak K,Hertel O,Pedersen C,Overvad K,Tjønneland A,Raaschou-Nielsen Odoi
10.1016/j.envres.2012.05.012subject
Has Abstractpub_date
2012-10-01 00:00:00pages
130-6eissn
0013-9351issn
1096-0953pii
S0013-9351(12)00182-Xjournal_volume
118pub_type
杂志文章abstract：BACKGROUND:Exposure to traffic pollution has been linked to numerous adverse health endpoints. Despite this, limited data examining traffic exposures during realistic commutes and acute response exists. OBJECTIVES:We conducted the Atlanta Commuters Exposures (ACE-1) Study, an extensive panel-based exposure and health ...
journal_title：Environmental research
pub_type： 杂志文章
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更新日期：2014-08-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2015.02.011
更新日期：2015-04-01 00:00:00
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pub_type： 杂志文章
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更新日期：2020-02-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
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更新日期：1994-07-01 00:00:00
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pub_type： 杂志文章
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更新日期：2010-08-01 00:00:00
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pub_type： 杂志文章
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更新日期：2020-03-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
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更新日期：2016-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
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更新日期：2019-09-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.01.047
更新日期：2019-04-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2010.03.002
更新日期：2010-05-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.2001.4281
更新日期：2001-09-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(05)80153-7
更新日期：1990-06-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.07.020
更新日期：2017-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2012.06.001
更新日期：2013-01-01 00:00:00
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journal_title：Environmental research
pub_type： 历史文章,杂志文章
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更新日期：2012-07-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
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更新日期：1994-02-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章,多中心研究
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更新日期：1995-08-01 00:00:00
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journal_title：Environmental research
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更新日期：2020-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1999.3990
更新日期：1999-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2018.03.038
更新日期：2018-07-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章,评审
doi：10.1006/enrs.1993.1131
更新日期：1993-10-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2018.08.028
更新日期：2018-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.108717
更新日期：2019-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.109092
更新日期：2020-03-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(84)90129-4
更新日期：1984-10-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(05)80106-9
更新日期：1991-10-01 00:00:00
