Abstract:
:We have developed a graphical image database CancerProView (URL: http://cancerproview.dmb.med.keio.ac.jp/php/cpv.html) to assist the search for alterations of the motifs/domains in the cancer-related proteins that are caused by mutations in the corresponding genes. For the CancerProView, we have collected various kinds of data on 180 cancer-related proteins in terms of the motifs/domains, genomic structures of corresponding genes, and 109 charts of the protein interaction pathways. Moreover, we have collected the relevant data on 1041 reference genes including 197 non-cancer disease-associated genes, and the nucleotide sequences for 2011 full-length cDNA's and the alternatively spliced transcript variants. Thus, the CancerProView database system would provide valuable information to facilitate basic cancer research as well as for designing new molecular diagnosis and drug discovery for cancers. The CancerProView database can be operated via Internet with any Web browser, and the system is freely available to interested users without ID and password.
journal_name
Genomicsjournal_title
Genomicsauthors
Mitsuyama S,Shimizu Ndoi
10.1016/j.ygeno.2012.05.011subject
Has Abstractpub_date
2012-08-01 00:00:00pages
81-92issue
2eissn
0888-7543issn
1089-8646pii
S0888-7543(12)00104-8journal_volume
100pub_type
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