Abstract：
:Currently, it is clear that primary hypertension begins in childhood and that it contributes to the early development of chronic kidney disease (CKD). Hypertension also increases the risk of cardiovascular morbidity and mortality, and that risk rises as blood pressure levels escalate. As among adult patients, overweight and obesity rates are on the rise among children and adolescents with primary hypertension and can develop target organ damage including left ventricular hypertrophy. An elevated level of C-reactive protein (CRP) and microalbuminuria are early manifestations of cardiovascular disease and CKD in hypertensive patients. Lifestyle interventions are recommended for all children with hypertension. Pharmacologic therapy should be added for symptomatic children, those with stage 2 hypertension, and children with prehypertension and stage 1 hypertension who exhibit an insufficient response to lifestyle modifications. Although the recommendations for choice of drugs generally are similar for children and adults, dosages for children should be lower, based on weight, and adjusted very carefully. Medications that are effective and safe for children and adolescents include thiazide diuretics, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, beta-blockers, and calcium channel-blockers. Hypertension is not being detected early enough for initiation of a treatment regimen to reduce death and disability. Initiatives should be undertaken to make health care providers and the general population more aware of the seriousness of hypertension in children and adolescents. This review focuses on the principles underlying the importance of a team approach for hypertension control, especially one that incorporates increased data sharing using enhanced health information technology for early detection and intervention.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Assadi Fdoi
10.1007/s00246-012-0333-5subject
Has Abstractpub_date
2012-10-01 00:00:00pages
1013-20issue
7eissn
0172-0643issn
1432-1971journal_volume
33pub_type
杂志文章,评审abstract：:Very young mammals have an impressive cardiac regeneration capacity. In contrast, cardiac regeneration is very limited in adult humans. The hearts of young children have a higher regenerative capacity compared with adults, as, for example, seen after surgical correction of an anomalous left coronary artery arising fro...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-015-1120-x
更新日期：2015-04-01 00:00:00
abstract：:Ebstein anomaly of mitral valve (MV) is an extremely rare congenital heart disease. In the current report, we present a case of Ebstein of MV that was diagnosed prenatally. Fetal echocardiogram showed that the posterior leaflet of MV was tethered to the lateral wall of left ventricle (LV) with downward displacement in...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1903-y
更新日期：2018-08-01 00:00:00
abstract：:Left ventricular (LV) function is impaired by increased afterload in neonates with severe coarctation of the aorta, which may result in endocardial fibroelastosis. Repair of the coarctation usually solves the problem, with LV function normalizing after a few weeks. This report describes a patient who underwent success...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9595-y
更新日期：2010-02-01 00:00:00
abstract：:This study aimed to assess the technical aspects of atrial septal defect (ASD) closure using the Amplatzer septal occluder (ASO) and the Gore Helex septal occluder (GHSO) for infants weighing less than 8 kg and to determine the safety, effectiveness, and near-to-intermediate-term outcome of the closure. The Mid-Atlant...
journal_title：Pediatric cardiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00246-014-0905-7
更新日期：2014-10-01 00:00:00
abstract：:Exercise testing can highlight repolarisation abnormalities in adults with coronary artery disease. Late after Kawasaki disease (KD), increased QT dispersion (QTd) has been reported on resting ECG in children, but there are no reported studies of QTd during exercise. Our objective was to determine the pattern of QTd r...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0201-3
更新日期：2012-06-01 00:00:00
abstract：:This study reviewed different types of primary cardiac and mediastinal tumors in infants and children as well as their clinical presentation and management. Altogether, 34 consecutive patients followed from 1976 through December 2005 were analyzed. Of these 34 patients, 14 (41%) underwent surgery and 20 (59%) with rha...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-008-9256-6
更新日期：2008-11-01 00:00:00
abstract：:A two-year-old child who had had palliative surgery as a neonate for an absent right atrioventricular connection and double-inlet ventricle was shown to be developmentally retarded. Trisomy for the short arm of chromosome 8 was demonstrated, resulting from a familial 8:13 translocation, with a high risk of recurrence....
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02306750
更新日期：1984-01-01 00:00:00
abstract：:Fetal atrioventricular dissociation is a dysrhythmia associated with significant antenatal and postnatal morbidity and mortality. We present a case of a 19-week-old fetus with atrioventricular dissociation, which spontaneously resolved. The mother had no signs of autoimmune disease. The fetus had an uneventful gestati...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900366
更新日期：1998-11-01 00:00:00
abstract：:Ischemic myocardial damage was identified as a complicating feature in the clinical course of 12 newborn infants who died in congestive failure with cerebral arteriovenous malformation. Electrocardiograms of 11 patients showed signs of chamber hypertrophy and T wave and ST segment features of varying degree compatible...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02281003
更新日期：1983-01-01 00:00:00
abstract：:Acute kidney injury (AKI) is a potential complication for children with congenital heart disease (CHD) after cardiopulmonary bypass (CPB) surgery. This study was designed to investigate and compare the predictive values of urinary biomarkers for AKI after CPB surgery in infants and young children and to determine the ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0563-6
更新日期：2013-04-01 00:00:00
abstract：:Anatomic evidence of intrauterine closure of ventricular septal defects (VSDs) has been reported rarely. Between 1985 and 1990, 112 autopsies were performed at the Mayo Clinic on third trimester stillborns and infants who died during the first week of life. There were 21 (19%) cases of congenital heart disease. VSD wa...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00797004
更新日期：1994-01-01 00:00:00
abstract：:Long-term oral warfarin is recommended in pediatric Kawasaki disease patients with large coronary artery aneurysms; however, heterogeneity is considerable. This study aimed to determine variables affecting warfarin dosage in Kawasaki disease. The enrolled individuals (194 children) were divided into four groups: (1) C...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1957-x
更新日期：2019-01-01 00:00:00
abstract：:Pediatric cardiothoracic surgery is often associated with low cardiac output in the postoperative period. This study sought to determine whether increasing heart rate via temporary atrial pacing is beneficial in augmenting cardiac output. Patients younger than 18 years who underwent cardiothoracic surgery and had no p...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0687-3
更新日期：2013-10-01 00:00:00
abstract：:Two-dimensional echocardiography was performed on a patient with criss-cross atrioventricular (AV) relationship and ventriculo-arterial discordance. A systematic approach from the subcostal area revealed the complex cardiac pathology including the criss-cross AV relationship of right and left heart, indicating that th...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02427034
更新日期：1982-01-01 00:00:00
abstract：:We present a case of congenital pulmonary systemic collateral vein associated with truncus arteriosus. Pulmonary systemic collateral vein with nonobstructed left atrial egress is different from those with obstructed left atrial egress in that it is functionally redundant. Including this case, 8 patients among 33 repor...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-002-0439-2
更新日期：2004-01-01 00:00:00
abstract：:The aim of this study was to clarify the association of clinical characteristics of unexplained syncope with the outcome of the head-up tilt test (HUT) in children. A total of 47 patients with unexplained syncope were classified into two groups according to their outcomes of HUT: the positive response group and the ne...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0513-4
更新日期：2004-07-01 00:00:00
abstract：:Patency of the ductus arteriosus (PDA) is a common finding in small premature infants. Recently pulsed-Doppler-cross sectional echocardiography (PD-CSE) has been successfully used in these patients. We report a case of a premature infant with an unusual PD-CSE pattern. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02279882
更新日期：1988-01-01 00:00:00
abstract：:Acute pulmonary vasodilator testing (AVT) is essential to determining the initial therapy for children with pulmonary arterial hypertension (PAH). This study aimed to report the initial experience with inhaled treprostinil used for AVT in children with PAH and to evaluate the hemodynamic change after inhaled treprosti...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0597-9
更新日期：2013-04-01 00:00:00
abstract：:A newborn infant with familial Wolff-Parkinson-White (WPW) syndrome presented with a supraventricular tachycardia of 300 beats/min, refractory to digoxin and flecainide administration. Serial electropharmacologic tests were performed via the esophagus before and during oral therapy with verapamil at 40, 80, and 60 mg ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02238370
更新日期：1990-10-01 00:00:00
abstract：:The hospitalization of a child for cardiac surgery is known to be a stressful experience for parents. However, little is known about the time course or the relationships between parental stress and the child's actual or perceived recovery. This research aimed to investigate pre- and postoperative parental stress and t...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-010-9726-5
更新日期：2010-10-01 00:00:00
abstract：:Vitamin D has anti-inflammatory properties, and deficiency is prevalent in children. There is a paucity of data regarding vitamin D status and its correlation with low-grade inflammation and vasculature. We prospectively enrolled 25 children, 9-11 years old (13 male); 21 obese. Eight atherosclerosis-promoting risk fac...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1162-0
更新日期：2015-10-01 00:00:00
abstract：:Although transthoracic echocardiography (TTE) is the first-line examination for the study of coronary lesions in Kawasaki disease, CT coronary angiography (CTCA) is increasingly used and showed good results. Our aim is to evaluate the contribution of CTCA in the detection of coronary lesions and to compare its results...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-2044-z
更新日期：2019-02-01 00:00:00
abstract：:Various agents have been suggested as causal or associated factors in the pathogenesis of Kawasaki disease (KD); however, the underlying factors of KD remain unknown. Plasma exchange is one of the most effective treatments for the acute phase of KD. This indicates that plasma may contain factors associated with the pa...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0329-1
更新日期：2012-12-01 00:00:00
abstract：:We report the placement of an implantable cardiac defibrillator as preventative treatment in a 2-year-old with long QT syndrome. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-5230-5
更新日期：2004-07-01 00:00:00
abstract：:The aim of this study was to evaluate by Doppler echocardiography whether administration of transdermal nitroglycerin (NTG) to children with congestive heart failure could modify mitral flow velocity profile with redistribution of left ventricular filling to late diastole, suggesting preload reduction of the left vent...
journal_title：Pediatric cardiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s002460010144
更新日期：2001-01-01 00:00:00
abstract：:A patient with pulmonary valve stenosis associated with pseudohypertrophic muscular dystrophy is reported. The anomalies were detected by two-dimensional echocardiography and elevated serum enzymes, conformed by right ventriculography and muscles biopsy. The association between these two pathologies is unknown. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-001-0051-x
更新日期：2002-03-01 00:00:00
abstract：:We describe a patient diagnosed with a small atrial septal defect (3-4 mm) that had grown to 24 mm in diameter over a six-year period. Timing of transcatheter intervention may be affected by growth of the atrial septal defect and this reports the first case of an atrial septal defect outgrowing the possibility of tran...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-001-0068-1
更新日期：2002-09-01 00:00:00
abstract：:Over the past decade, revolutionary advances in ultrasound imaging technology have allowed the study of the evolution of congenital heart disease during fetal life. The frustration arising from watching the prenatal progression of severe semilunar valve obstructions and therapy-refractory fetal arrhythmias has prompte...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-001-0197-6
更新日期：2002-05-01 00:00:00
abstract：:Right ventricular (RV) pacing can be associated with impairment of left ventricular (LV) function due to electrical dyssynchrony and myocardial remodeling (Janousek et al. in J Cardiovasc Electrophysiol 15:470-474, 2004). RV-pacing induced ventricular dysfunction is reversible by techniques such as biventricular pacin...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-017-1629-2
更新日期：2017-08-01 00:00:00
abstract：:Beta-blocker therapy is one of the principal therapies for congenital long-QT syndrome (LQTS). However, breakthrough cardiac events occur while being treated with beta-blockers. We sought to determine the frequency of and clinical correlates underlying beta-blocker therapy failures in genotyped, symptomatic LQTS proba...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0567-3
更新日期：2004-09-01 00:00:00
