当前位置： SCI文献检索 > RESPIRATORY MEDICINE期刊下所有文献 > Respiratory movement and pain thresholds in airway environmental sensitivity, asthma and COPD.

Respiratory movement and pain thresholds in airway environmental sensitivity, asthma and COPD.

Abstract：

INTRODUCTION:Patients with "sensory hyperreactivity" (SHR) have airway environmental sensitivity, chronic cough and dyspnoea. Cough, chest discomfort and sense of difficulties getting air are some of the symptoms these patients seek medical attendance for. The patients have increased cough sensitivity to inhaled capsaicin, mediated by ion channel receptors on sensory nerves also known to react to pain stimuli. Whether a link exists between capsaicin airway sensitivity and pain sensitivity has not yet been evaluated. The aim was to investigate chest mobility, respiratory movement and pain sensitivity in SHR patients compared with patients with asthma, chronic obstructive pulmonary disease (COPD) and alleged healthy control subjects. METHODS:Thirty-five patients diagnosed with SHR, 19 with COPD, 32 with asthma and 28 control subjects were included. Chest expansion was measured with a measuring tape and thoracic and abdominal movement with light sensors. Pain sensitivity was assessed using a pressure algometer. RESULTS:Groups differed significantly in lung function, respiratory rate and pain sensitivity but also in chest expansion and abdominal breathing movement. In comparison with the control and asthma groups but not the COPD patients, SHR patients had an increased respiratory rate and reduced abdominal movement during deep breathing. All patient groups showed lower pain thresholds than the controls. CONCLUSION:Patients with SHR have evident signs of dysfunctional breathing and appeared to be most similar to the COPD group except for lung function. Lower pain thresholds among the patients indicate a general up-regulation of the sensory nerve system.

journal_name

Respir Med

journal_title

Respiratory medicine

authors

Johansson EL,Ternesten-Hasséus E,Olsén MF,Millqvist E

doi

10.1016/j.rmed.2012.03.011

subject

Has Abstract

pub_date

2012-07-01 00:00:00

pages

1006-13

issue

7

eissn

0954-6111

issn

1532-3064

pii

S0954-6111(12)00121-7

journal_volume

106

pub_type

杂志文章

相关文献

RESPIRATORY MEDICINE文献大全
  • Serum and pleural fluid levels of CA50 in malignant and tuberculous effusions.

    abstract：:The measurement of CA50 in serum and pleural fluid by immunoradiometric assay was presented in 45 (27 malignancy and 18 tuberculosis) patients with pleural effusion. The mean CA50 level in malignant effusion (89.26 +/- 122.32 U ml-1) was significantly higher than that in tuberculous effusion (5.18 +/- 8.65 U ml-1) (P ...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/0954-6111(94)90170-8

    authors： Yang SZ,Ji SQ

    更新日期：1994-01-01 00:00:00

  • Lack of association between KIR and HLA-C type and susceptibility to idiopathic bronchiectasis.

    abstract：INTRODUCTION:Idiopathic bronchiectasis is a poorly defined disease characterised by persistent inflammation, infection and progressive lung damage. Natural killer (NK) cells provide a major defense against infection, through the interaction of their surface receptors, including the activating and inhibitory killer immu...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2014.05.017

    authors： McDonnell MJ,Anwar GA,Rutherford RM,De Soyza A,Worthy S,Corris PA,Lordan JL,Bourke S,Afolabi G,Ward C,Middleton P,Middleton D

    更新日期：2014-08-01 00:00:00

  • The outcome of community acquired pneumonia treated on the intensive care unit.

    abstract：:Eighteen patients with community acquired pneumonia required intensive care for severe or progressive hypoxaemia, rising arterial carbon dioxide tension or respiratory arrest, and 17 received intermittent positive pressure ventilation. Thirteen survived to leave hospital and 12 are long term survivors. Ventilation was...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/s0954-6111(08)80087-x

    authors： Alkhayer M,Jenkins PF,Harrison BD

    更新日期：1990-01-01 00:00:00

  • Validation of ATS clinical practice guideline cut-points for FeNO in asthma.

    abstract：BACKGROUND:The American Thoracic society (ATS) has suggested using fractional exhaled nitric oxide (FeNO) to monitor the level of eosinophilic (EOS) airway inflammation in asthma, but validation of the proposed cut-points is required in real-life populations. OBJECTIVE:To validate FeNO cut-points suggested by ATS in r...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2018.09.014

    authors： Jeppegaard M,Veidal S,Sverrild A,Backer V,Porsbjerg C

    更新日期：2018-11-01 00:00:00

  • Expression of integrins in human cultured mesothelial cells: the roles in cell-to-extracellular matrix adhesion and inhibition by RGD-containing peptide.

    abstract：:Integrins play key roles in cell-to-cell and cell-to-extracellular matrix (ECM) adhesion. We investigated integrin expression on pleural mesothelial cells (PMCs) and the inhibitory effect of arginine-glycine-asparate (RGD)-containing peptide on the adhesion of PMCs to fibronectin and collagen. Using flow cytometry and...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1053/rmed.2000.1026

    authors： Liaw YS,Yu CJ,Shun CT,Lee YC,Kuo SH,Luh KT,Yang PC

    更新日期：2001-03-01 00:00:00

  • Reassessment of asthma management in an accident and emergency department.

    abstract：:To determine if shortcomings in asthma management in the Accident and Emergency (A & E) department identified in a previous (1983) study (Reed et al. Thorax 1985; 40: 897-902) had been corrected, we retrospectively reviewed the case records of patients attending with asthma between December 1987 and November 1988. The...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/s0954-6111(06)80180-0

    authors： Chidley KE,Wood-Baker R,Town GI,Sleet RA,Holgate ST

    更新日期：1991-09-01 00:00:00

  • Ulcerative colitis responsive to smoking and to nicotine chewing gum in a patient with alpha 1 anti-trypsin deficiency.

    abstract：:Ulcerative colitis is one of the few diseases in which smoking appears to confer some benefit (1). We report a patient whose ulcerative colitis deteriorated on several occasions on stopping cigarettes, and improved on restarting smoking. As a result, she continued smoking despite developing airflow limitation and seve...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/0954-6111(95)90235-x

    authors： Watson JP,Lewis RA

    更新日期：1995-10-01 00:00:00

  • Staging of non-small cell lung cancer (NSCLC): a review.

    abstract：:Lung cancer remains the most common cause of cancer-related mortality in Scotland, accounting for 28.9% of all cancer deaths in 2007. (1) Current guidelines recommend assessment of patient fitness and operability by a multi-disciplinary team when selecting management options. (2-6) Two of the most important prognostic...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,评审

    doi：10.1016/j.rmed.2010.08.005

    authors： Tsim S,O'Dowd CA,Milroy R,Davidson S

    更新日期：2010-12-01 00:00:00

  • Effects of allergen exposure on methacholine and AMP-induced air trapping in pollen-sensitive subjects.

    abstract：BACKGROUND:The effect of pro-inflammatory stimuli on bronchoconstrictor-induced air trapping has not been studied. OBJECTIVE:To determine the effect of natural allergen exposure, a pro-inflammatory stimulus, on methacholine- and adenosine 5'-monophospate (AMP)-induced air trapping. METHODS:Airway responsiveness to me...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2010.11.023

    authors： Lopez V,Prieto L,Perez C,Barato D,Marin J

    更新日期：2011-06-01 00:00:00

  • Predicting the need for ICU admission in community-acquired pneumonia.

    abstract：BACKGROUND:Multiple criteria have been proposed to define community-acquired pneumonia (CAP) severity and predict ICU admission. Validity studies have found differing results. We tested four models to assess severe CAP built upon the criteria included in the 2007 IDSA/ATS guidelines, hypothesizing that a model providin...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2019.07.007

    authors： Gearhart AM,Furmanek S,English C,Ramirez J,Cavallazzi R

    更新日期：2019-08-01 00:00:00

  • Cardiopulmonary exercise testing and second-line pulmonary function tests to detect obstructive pattern in symptomatic smokers with borderline spirometry.

    abstract：BACKGROUND:The need for additional research on symptomatic smokers with normal spirometry has been recently emphasized. Albeit not meeting criteria for Chronic obstructive pulmonary disease (COPD) diagnosis, symptomatic smokers may experience activity limitation, evidence of airway disease, and exacerbations. We, there...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2017.04.006

    authors： Di Marco F,Terraneo S,Job S,Rinaldo RF,Sferrazza Papa GF,Roggi MA,Santus P,Centanni S

    更新日期：2017-06-01 00:00:00

  • T lymphocyte subset abnormalities in the blood and lung in pulmonary arterial hypertension.

    abstract：RATIONALE:Mounting data suggest that immune cell abnormalities participate in the pathogenesis of pulmonary arterial hypertension (PAH). OBJECTIVE:To determine whether the T lymphocyte subset composition in the systemic circulation and peripheral lung is altered in PAH. METHODS:Flow cytometric analyses were performed...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2009.10.004

    authors： Austin ED,Rock MT,Mosse CA,Vnencak-Jones CL,Yoder SM,Robbins IM,Loyd JE,Meyrick BO

    更新日期：2010-03-01 00:00:00

  • Efficacy of salbutamol via Easyhaler unaffected by low inspiratory flow.

    abstract：:The fine particle dose delivered via dry powder inhalers (DPIs) is often affected by the inspiratory flow rate generated during inhalation. This has clinical implications, since the fine particle dose determines the amount of drug reaching the lungs. With Easyhaler DPI the fine particle dose remains relatively constan...

    journal_title：Respiratory medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1053/rmed.2000.0959

    authors： Koskela T,Malmström K,Sairanen U,Peltola S,Keski-Karhu J,Silvasti M

    更新日期：2000-12-01 00:00:00

  • A retrospective analysis of the pathogens in the airways of patients with primary ciliary dyskinesia.

    abstract：INTRODUCTION:Primary ciliary dyskinesia (PCD) is a rare genetically heterogeneous disorder of motile cilia, which leads to recurrent and chronic airway infections. Detailed information about infection causing pathogens is scarce. With this study, we aimed to determine the prevalence and susceptibility of the most commo...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2019.08.009

    authors： Roden L,Görlich D,Omran H,Peters G,Große-Onnebrink J,Kahl BC

    更新日期：2019-09-01 00:00:00

  • A comparison of surfactant delivery with conventional mechanical ventilation and partial liquid ventilation in meconium aspiration injury.

    abstract：:The objective of this study was to compare surfactant (SF) distribution and physiological effects after standard SF delivery during conventional mechanical ventilation (CMV) with that using partial liquid ventilation (PLV). A model of meconium aspiration syndrome (MAS) was developed using two groups of adult rats (n =...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1053/rmed.2001.1114

    authors： Chappell SE,Wolfson MR,Shaffer TH

    更新日期：2001-07-01 00:00:00

  • Cystic fibrosis in children from ethnic minorities in the West Midlands.

    abstract：BACKGROUND:We have observed that Doctors often perceive that cystic fibrosis (CF) is exceptionally rare in non-whites, and that this bias has repeatedly resulted in diagnostic delay. We therefore compared the age at diagnosis, genetic features and relative prevalence of CF in non-whites and white patients in the West M...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/s0954-6111(05)80065-4

    authors： Spencer DA,Venkataraman M,Higgins S,Stevenson K,Weller PH

    更新日期：1994-10-01 00:00:00

  • Indacaterol vs tiotropium in COPD patients classified as GOLD A and B.

    abstract：INTRODUCTION:According to current GOLD strategy, patients with COPD classified as groups A and B may be treated with inhaled bronchodilators, either long-acting β2-agonist (LABA) or long-acting muscarinic antagonist (LAMA). However, there is little guidance on which class of agent is preferred and a lack of prospective...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.rmed.2015.05.012

    authors： Mahler DA,Kerstjens HA,Donohue JF,Buhl R,Lawrence D,Altman P

    更新日期：2015-08-01 00:00:00

  • Bacterial extracts for the prevention of acute exacerbations in chronic obstructive pulmonary disease: a point of view.

    abstract：:Given the high prevalence of chronic obstructive pulmonary disease (COPD), the impact of exacerbations on quality of life, and the costs incurred, effective ways for the prevention of exacerbations, and for reductions in the severity and duration of COPD symptoms are needed. Bacterial immunostimulation has been advoca...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,评审

    doi：10.1016/j.rmed.2007.11.002

    authors： Cazzola M,Rogliani P,Curradi G

    更新日期：2008-03-01 00:00:00

  • A profile of volatile organic compounds in breath discriminates COPD patients from controls.

    abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is an inflammatory condition characterized by oxidative stress and the formation of volatile organic compounds (VOCs) secreted via the lungs. We recently developed a methodological approach able to identify profiles of VOCs in breath unique for patient groups. Her...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2009.10.018

    authors： Van Berkel JJ,Dallinga JW,Möller GM,Godschalk RW,Moonen EJ,Wouters EF,Van Schooten FJ

    更新日期：2010-04-01 00:00:00

  • Effects of inspiratory muscle training on postural stability, pulmonary function and functional capacity in children with cystic fibrosis: A randomised controlled trial.

    abstract：BACKGROUND:Previous research has found conflictive results regarding the benefits of inspiratory muscle training (IMT) for cystic fibrosis (CF) patients. Also, involvement of postural stability is a rising concern in chronic lung diseases but its role in CF patients is poorly understood. Our aim was to investigate the ...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.rmed.2019.01.013

    authors： Zeren M,Cakir E,Gurses HN

    更新日期：2019-03-01 00:00:00

  • Summing up 100 years of asthma.

    abstract：:In this review, we aim to lead the readers through the historical highlights of pathophysiological concepts and treatment of asthma. Understanding the nature and links of asthma has modeled our diagnostic, pathophysiological and therapeutic thinking and acting. The recognition of its heterogeneous nature in combinatio...

    journal_title：Respiratory medicine

    pub_type： 历史文章,杂志文章,评审

    doi：10.1016/j.rmed.2006.12.004

    authors： Diamant Z,Boot JD,Virchow JC

    更新日期：2007-03-01 00:00:00

  • The effect of different concentrations of lactose powder on the airway function of adult asthmatics.

    abstract：:Lactose is widely used as a carrier of drugs in inhalation devices for asthmatic patients, but some clinicans have suspected that it may cause bronchoconstriction. Only a few studies have been done to examine this and the results are not uniform. This study was conducted to determine the effects of inhalation grade la...

    journal_title：Respiratory medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1053/rmed.2001.1150

    authors： Thoren P,Wallin A,Whitehead PJ,Sandström T

    更新日期：2001-11-01 00:00:00

  • Etiology of community-acquired pneumonia treated in an ambulatory setting.

    abstract：BACKGROUND:Very few studies have addressed the etiology of community-acquired pneumonia (CAP) treated in an ambulatory setting. METHODS:Patients were recruited from physicians' offices and from Emergency Rooms in Canada. Pneumonia was defined as two or more respiratory symptoms and signs and a new opacity on chest rad...

    journal_title：Respiratory medicine

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.rmed.2004.05.010

    authors： Marrie TJ,Poulin-Costello M,Beecroft MD,Herman-Gnjidic Z

    更新日期：2005-01-01 00:00:00

  • Computed tomographic evaluation of the role of craniofacial and upper airway morphology in obstructive sleep apnea in Chinese.

    abstract：OBJECTIVES:To evaluate the relationship between cephalometric parameters, upper airway morphological factors and obstructive sleep apnea (OSA) in Chinese subjects. DESIGN:Polysomnogram (PSG) were performed and scored using standard criteria. Supine lateral cephalometric parameters and pharyngeal cross-sectional areas ...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2003.10.009

    authors： Lam B,Ooi CG,Peh WC,Lauder I,Tsang KW,Lam WK,Ip MS

    更新日期：2004-04-01 00:00:00

  • Increased content of thiobarbituric acid-reactive substances and hydrogen peroxide in the expired breath condensate of patients with stable chronic obstructive pulmonary disease: no significant effect of cigarette smoking.

    abstract：:The imbalance between oxidants and antioxidants is known to play an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Cigarette smoking is the most frequent factor responsible for development of COPD by leading to oxidant overload in the lower airways, due to presence of its own oxida...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1053/rmed.1999.0574

    authors： Nowak D,Kasielski M,Antczak A,Pietras T,Bialasiewicz P

    更新日期：1999-06-01 00:00:00

  • Effect of cyclosporin A on inflammatory cytokine production by human alveolar macrophages.

    abstract：:Cyclosporin A (CsA) is an immunomodulator drug that has been used in the treatment of several types of advanced pulmonary interstitial disease. This beneficial effect occurs mainly in circumstances in which alveolitis due to CD4 lymphocytes is absent, suggesting that CsA acts on other types of cells. The present study...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/s0954-6111(98)90002-6

    authors： Losa García JE,Mateos Rodríguez F,Jiménez López A,García Salgado MJ,Martín de Cabo MR,Pérez Losada J,Pérez Arellano JL

    更新日期：1998-05-01 00:00:00

  • Advanced cryptogenic fibrosing alveolitis: preliminary report on treatment with cyclosporin A.

    abstract：:Seven patients with fibrosing alveolitis who failed to respond to prednisolone and cyclophosphamide and were deteriorating, were treated with cyclosporin A. An initial favourable response was seen but was not maintained. When compared to a control population, matched for the extremely severe disease present in the tre...

    journal_title：Respiratory medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0954-6111(89)80196-9

    authors： Alton EW,Johnson M,Turner-Warwick M

    更新日期：1989-07-01 00:00:00

  • Methacholine challenge in pre-school children--which outcome measure?

    abstract：:The aim of our study was to evaluate the utility of interrupter resistance (R(int)), transcutaneous oximetry and auscultation as outcome measures for a recently suggested tripling-dose methacholine (Mch) challenge in pre-school children. We studied 57 children aged 3-6 years. R(int) was measured at baseline and after ...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2007.07.002

    authors： Kivastik J,Gibson AM,Primhak RA

    更新日期：2007-12-01 00:00:00

  • Cost of influenza and influenza-like syndromes (I-LSs) in Italy: Results of a cross-sectional telephone survey on a representative sample of general population.

    abstract：OBJECTIVES:Influenza and Influenza-like syndromes (I-LSs) are very common events in general practice, and their relevance is frequently underestimated. Aim of the study was to assess the economic impact of influenza and Influenza-like syndromes (I-LSs) in the Italian general population by using real-world data from a r...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2018.07.001

    authors： Dal Negro RW,Turco P,Povero M

    更新日期：2018-08-01 00:00:00

  • Electrocardiographic changes in obstructive sleep apnoea syndrome.

    abstract：:Obstructive sleep apnoea syndrome (OSAS) has acute and chronic effects on the cardiovascular system. Both right and left sides of the heart are affected. Electrocardiographic pattern was studied in 190 OSAS patients. One or more of the following were found: persistent deep S in lateral chest leads V5, V6 (79%), left a...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/s0954-6111(98)90027-0

    authors： Khalil MM,Rifaie OA

    更新日期：1998-01-01 00:00:00