Quantitative trait loci for resistance to infection in sheep using a live Salmonella Abortusovis vaccine.

Abstract:

:Quantitative trait loci (QTL) mapping for susceptibility to a Salmonella Abortusovis vaccinal strain was performed using an experimental design involving 30 Romane sheep sire families (1216 progenies). Nine QTL corresponding to bacterial load, weight variations and antibody response criteria were mapped on eight chromosomes, including the major histocompatibility complex area on chromosome 20. Surprisingly, none was found to be significant in the SLC11A1 region (formerly NRAMP1) that has been shown to influence Salmonella susceptibility in other species.

journal_name

Anim Genet

journal_title

Animal genetics

authors

Lantier I,Moreno CR,Berthon P,Sallé G,Pitel F,Schibler L,Gautier-Bouchardon AV,Boivin R,Weisbecker JL,François D,Bouix J,Cribiu EP,Elsen JM,Lantier F

doi

10.1111/j.1365-2052.2011.02291.x

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

632-5

issue

5

eissn

0268-9146

issn

1365-2052

journal_volume

43

pub_type

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