Myoid angioendothelioma of the spleen mimicking metastatic disease in a patient with rectal cancer: a radiologic-pathologic correlation.

Abstract:

:Myoid angioendothelioma of the spleen is an uncommon, benign vascular tumor that is morphologically characterized by a composite of vascular spaces and stromal cells with myoid feature. Herein, we report a case of the myoid angioendothelioma of the spleen, concurrent with rectal adenocarcinoma. A 41-year-old woman presented with hematochezia for several weeks. Grossly, the rectal mass was a 2.5 × 2-cm ulcerative fungating lesion. The splenic mass was a 2.2 × 2-cm well-circumscribed lesion. Microscopically, the rectal mass was a well-differentiated adenocarcinoma that invaded into the pericolic adipose tissue. The splenic mass was composed of slit-like vascular spaces and fascicles of elongated stromal cells. Vascular endothelial cells were immunopositive for CD31, factor VIII-related antigen, and CD34 but negative for CD8. Stromal cells were immunopositive for smooth muscle actin but negative for desmin.

journal_name

Ann Diagn Pathol

authors

Jang KY,Chung MJ,Moon WS,Sohn MH,Hwang SB,Lee MR,Lee H,Park HS

doi

10.1016/j.anndiagpath.2012.03.001

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

108-12

issue

1

eissn

1092-9134

issn

1532-8198

pii

S1092-9134(12)00033-0

journal_volume

17

pub_type

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