Abstract：
:The Na+/H+ exchanger 1 (NHE1) plays a significant role in acidifying the tumour microenvironment, potentially contributing to the tumour's malignant potential. The mechanism by which NHE1 mediates cell invasion and migration, especially in human tongue squamous cell carcinoma (hTSCC), is unknown. In this study, the authors demonstrated that inhibition of NHE1 by cariporide (HOE642) suppressed the invasion and migration of Tca8113 cells under hypoxic conditions. Hypoxia also promoted the production of MMP-9, and the suppressive role of cariporide was enacted through the downregulation of MMP-9. The data demonstrated that NHE1 plays a role in hTSCC invasion and that NHE1 might be a new target for hTSCC treatment.
journal_name
Int J Oral Maxillofac Surgjournal_title
International journal of oral and maxillofacial surgeryauthors
Lv C,Yang X,Yu B,Ma Q,Liu B,Liu Ydoi
10.1016/j.ijom.2012.03.001subject
Has Abstractpub_date
2012-10-01 00:00:00pages
1206-10issue
10eissn
0901-5027issn
1399-0020pii
S0901-5027(12)00106-3journal_volume
41pub_type
杂志文章abstract：:In the surgical management of oral cancer the resection and reconstruction of the mobile tongue and soft palate are most important if function is to be maintained. The present trend towards primary laryngeal surgery for early disease has emphasized the importance of primary surgery if good functional outcomes can be a...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2005.09.005
更新日期：2006-03-01 00:00:00
abstract：:A critical review of the literature about risks and benefits of the removal of impacted 3rd molar teeth is presented in 4 categories: risk of non-intervention, risk of intervention, benefit of non-intervention and benefit of intervention. There are well-defined criteria for removal of impacted 3rd molar teeth. Absolut...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
doi：10.1016/s0901-5027(05)80447-3
更新日期：1992-02-01 00:00:00
abstract：:Use of stereolithographic models of the resection areas in mandibular tumor surgery allows for preoperative adapting of resection plates, and shortening operating time. Adapting reconstruction plates along the deformed resection contour, however, recreates the existing, unfavorable contour. The computer-aided procedur...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2005.07.012
更新日期：2006-02-01 00:00:00
abstract：:In cleft lip and palate patients the shape of the nose invariably changes in three dimensions (3D) due to rhinoplastic surgery. The purpose of this study was to evaluate stereophotogrammetry as a 3D method to document volumetric changes of the nose in patients with a cleft lip (CL) or cleft lip and palate (CLP) after ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2010.03.022
更新日期：2010-06-01 00:00:00
abstract：:Macroglossia is observed in the majority of paediatric patients diagnosed with Beckwith-Wiedemann syndrome and surgical treatment may be indicated. A 20-year retrospective study was performed to evaluate all patients with Beckwith-Wiedemann syndrome who underwent tongue reduction surgery at the authors' institution. A...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
doi：10.1016/j.ijom.2011.10.021
更新日期：2012-03-01 00:00:00
abstract：:A rare case of subcutaneous granuloma annulare of the eyelid is reported. A diabetic patient developed a unilateral periorbital tumorous mass. Biopsy revealed subcutaneous palisading granuloma. By microscopy and immunohistology, other granulomatous reactions including necrobiosis lipoidica could be ruled out. Since tr...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(06)80136-0
更新日期：1995-06-01 00:00:00
abstract：:A case of complete median cleft of the lower lip and mandible and bifid tongue with ankyloglossia is presented. Unlike other reported cases of similar disorders, no other abnormalities were present. A satisfactory result was achieved with early surgical correction of both hard- and soft-tissue defects. ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(06)80054-8
更新日期：1996-08-01 00:00:00
abstract：:Many clinical guidelines for investigating lymphomas advise that surgical excision biopsy (SEB) should be performed for a confident diagnosis. It is increasingly recognized in clinical practice that ultrasound-guided core needle biopsy (USCNB) is a reliable diagnostic technique. We aimed to investigate the diagnostic ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2020.07.005
更新日期：2020-07-29 00:00:00
abstract：:This study was performed to evaluate the use of three-dimensional (3D) strut plates for the surgical management of mandibular angle fractures and to determine the subsequent postoperative complication rate. Two hundred and twenty-two patients met the inclusion criteria for mandible angle fracture at the university hos...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2016.05.023
更新日期：2016-11-01 00:00:00
abstract：:The skull base is uniquely positioned to absorb force imparted to the craniofacial skeleton, thereby reducing brain injury. Less well understood is the effect of the direction of force imparted to the craniofacial skeleton on the severity of brain injury. Eighty-one patients from two UK major trauma centres who sustai...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ijom.2016.01.016
更新日期：2016-07-01 00:00:00
abstract：:The objective of this study was to assess changes in patient quality of life (QoL) after orthognathic surgery at the Kuwait University Dental Clinic. A self-administered Arabic version of the Orthognathic Quality of Life Questionnaire (OQLQ) and two different visual analogue scales (VAS) were used. Sixty-six patients ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2017.12.010
更新日期：2018-06-01 00:00:00
abstract：:A method of placing two endosteal implants with simultaneous bone grafting to the anterior mandible is described. This technique is simple to use, has minimal morbidity, and has produced good preliminary results. Retrospectively, 18 patients with a total of 36 implants were reviewed. An implant success rate of 91.6% w...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(96)80026-9
更新日期：1996-06-01 00:00:00
abstract：:This study reports the case of a patient with a severely resorbed mandible who was treated without a bone graft, using short implants, internal rigid fixation, rhBMP-2 and β-tricalcium phosphate. A 76-year-old woman, with a severely resorbed mandible (less than 3mm), reported a history of nearly 25 years of complete e...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2012.05.017
更新日期：2012-12-01 00:00:00
abstract：:The purpose of this study was to compare complication rates at the mandibulotomy site between patients receiving preoperative radiotherapy (RT) and those receiving postoperative RT during treatment for oral and oropharyngeal cancer where the surgical procedure required a mandibular osteotomy to gain access to the tumo...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2020.11.004
更新日期：2020-11-25 00:00:00
abstract：:Temporomandibular joint (TMJ) dislocation can be classified into four groups (anterior, posterior, lateral, and superior) depending on the direction of displacement and the location of the condylar head. All the groups are rare except for anterior dislocation. 'Inverse' TMJ dislocation is a bilateral anterior and supe...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2011.02.012
更新日期：2011-08-01 00:00:00
abstract：:Dislocation of the mandibular condyle into the middle cranial fossa is extremely rare. The authors present a case of superior dislocation of left condyle into the middle cranial fossa. The dislocated condyle was reduced successfully and then a flap of temporal muscle and a thin titanium network were used to repair the...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2010.02.028
更新日期：2011-01-01 00:00:00
abstract：:Peripheral ameloblastoma is an uncommon clinical entity, while ameloblastoma with distant metastasis is still more unusual. A case of peripheral ameloblastoma with left supraclavicular lymph node metastasis is presented here. ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(87)80131-5
更新日期：1987-04-01 00:00:00
abstract：:In this study, we compared the diagnostic accuracy and safety of fine-needle aspiration cytology and core-needle biopsy in patients with cervical lymphadenopathy or salivary gland tumour, and provided a basis for selecting the appropriate diagnostic method in clinical situations. A total of 278 patients were included ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2018.04.003
更新日期：2018-10-01 00:00:00
abstract：:Various aspects of aneuploidy are discussed including growth disturbance, developmental buffering and variable expression, generalized features of aneuploidy, and microdeletion syndromes. ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,评审
doi：10.1016/s0901-5027(89)80029-3
更新日期：1989-12-01 00:00:00
abstract：:The aim of this study was to analyze and compare the long-term clinical outcomes of mature third molar autotransplantation in surgically created sockets and fresh extraction sockets with regard to survival and functional success rates. A total of 65 third molars with completely formed roots were autotransplanted in 60...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2016.12.007
更新日期：2017-04-01 00:00:00
abstract：:The objective of this study was to propose a treatment protocol for patients with lateral prognathism based on the unilateral sagittal split ramus osteotomy (USSRO). This was a prospective study involving 31 patients with lateral prognathism, who required a bilateral sagittal split ramus osteotomy (BSSRO). Two groups ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2017.11.010
更新日期：2018-05-01 00:00:00
abstract：:A 71-year-old woman was referred to the clinic with extensive medication-related osteonecrosis of the jaw (MRONJ) involving the mandible. She had received 7 years of zoledronate therapy. On cone beam computed tomography, the MRONJ presented as a large sequestrum spanning from the left to the right condylar process, su...
journal_title：International journal of oral and maxillofacial surgery
pub_type：
doi：10.1016/j.ijom.2020.07.033
更新日期：2020-08-23 00:00:00
abstract：:A 7-year-old boy presented in whom a metaphyseal fibrous defect was diagnosed. The lesion was enucleated under local anesthesia. The postoperative course was uneventful and there have been no signs of recurrence as of 14 months after operation. Although rare, metaphyseal fibrous defect should be included in the differ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(05)80834-3
更新日期：1997-04-01 00:00:00
abstract：:This systematic review (SR) aimed to evaluate speech and velopharyngeal function (VPF) changes of patients with cleft palate (CLP) after maxillary advancement (MA) surgery. A two-phase PROSPERO-registered SR (CRD42019141370) was conducted following the PRISMA statements. Search strategies were developed for main datab...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章,meta分析
doi：10.1016/j.ijom.2020.07.030
更新日期：2021-01-01 00:00:00
abstract：:Orthognathic surgery aims to correct dentoskeletal and facial discrepancies. Treatment usually requires a minimum of 18 months, necessitating that patients are adequately satisfied with the treatment provided. This study aimed to assess the determinants of patient satisfaction following treatment. One hundred and eigh...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2018.07.013
更新日期：2019-02-01 00:00:00
abstract：:One hundred and forty four patients underwent magnetic resonance imaging (MRI) for evaluation of suspected internal derangement (ID) of the temporomandibular joint (TMJ). All scans were performed on a state-of-the-art scanner by highly experienced technologists and evaluated by a single Head and Neck/Maxillofacial rad...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2005.12.005
更新日期：2006-08-01 00:00:00
abstract：:Reduction of the expression of catenin is a crucial step in the pathogenesis, progression and prognosis of many epithelial cancers including squamous cell carcinomas (SCCs). Catenin expression in oral carcinomas was evaluated in relation to clinico-pathological features in order to determine its value as a prognostic ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2005.03.010
更新日期：2005-12-01 00:00:00
abstract：:Solitary myeloma may be the first manifestation of the disseminated form, known as multiple myeloma, and characterized by multiple skeletal lesions, general metabolic alterations, impairment of renal function and eventually death. Involvement of the jaws is not unusual, although infrequently reported. We present 2 cas...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(87)80095-4
更新日期：1987-08-01 00:00:00
abstract：:This case report documents one of the more unusual causes of a swelling in the preauricular region, a parotid sialocele. It illustrates the relationship of trauma to sialocele formation, while suggesting that most cases can be managed by a conservative regime. A suitable surgical solution is outlined for more persiste...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/s0901-5027(98)80310-x
更新日期：1998-04-01 00:00:00
abstract：:Seventeen patients, who presented mandibular fractures following third molar removal, were treated in the Department of Oral and Maxillofacial Surgery at the University Hospital Freiburg between 2000 and 2004. Clinical and radiological data were analysed to evaluate the possible risk of fracture following third molar ...
journal_title：International journal of oral and maxillofacial surgery
pub_type： 杂志文章
doi：10.1016/j.ijom.2005.03.003
更新日期：2005-10-01 00:00:00
