Involvement of multiple distinct Bordetella receptor proteins in the utilization of iron liberated from transferrin by host catecholamine stress hormones.

abstract：:The chromosomal gef gene of Escherichia coli is a member of the gef gene family which encodes strongly toxic proteins of about 50 amino acids. We demonstrate here that the Gef protein is detectable by anti-peptide antibodies. Furthermore, we show that Gef is anchored in the cytoplasmic membrane by the N-terminal part ...

journal_title：Molecular microbiology

authors： Poulsen LK,Refn A,Molin S,Andersson P

更新日期：1991-07-01 00:00:00

abstract：:The replication frequency of plasmid R1 is controlled by an unstable antisense RNA, CopA, which, by binding to its complementary target, blocks translation of the replication rate-limiting protein RepA. Since the degree of inhibition is directly correlated with the intracellular concentration of CopA, factors affectin...

journal_title：Molecular microbiology

authors： Söderbom F,Binnie U,Masters M,Wagner EG

更新日期：1997-11-01 00:00:00

abstract：:Oxidative stress serves as an important host/environmental signal that triggers a wide range of responses from the human pathogen Staphylococcus aureus. Among these, a thiol-based oxidation sensing pathway through a global regulator MgrA controls the virulence and antibiotic resistance of the bacterium. Herein, we rep...

journal_title：Molecular microbiology

authors： Chen PR,Nishida S,Poor CB,Cheng A,Bae T,Kuechenmeister L,Dunman PM,Missiakas D,He C

更新日期：2009-01-01 00:00:00

abstract：:Caulobacter crescentus chromosome replication is precisely coupled to a developmental cell cycle. Like most eubacteria, C. crescentus has a DnaA homologue that is presumed to initiate chromosome replication. However, the C. crescentus replication origin (Cori) lacks perfect consensus Escherichia coli DnaA boxes. Inste...

journal_title：Molecular microbiology

authors： Gorbatyuk B,Marczynski GT

更新日期：2001-04-01 00:00:00

abstract：:We have cloned, characterized and inactivated genes encoding putative UspA paralogues in Escherichia coli. The yecG (uspC), yiiT (uspD) and ydaA (uspE) genes were demonstrated to encode protein pro-ducts and these were mapped to spots in the E. coli proteomic database. Expression analysis using chromosomal transcripti...

journal_title：Molecular microbiology

authors： Gustavsson N,Diez A,Nyström T

更新日期：2002-01-01 00:00:00

abstract：:Eukaryotic cells have evolved a complex set of intracellular organelles, each of which possesses a specific complement of enzymes and performs unique metabolic functions. This compartmentalization of cellular functions provides a level of metabolic control not available to prokaryotes. However, it presents the eukaryo...

journal_title：Molecular microbiology

authors： Aitchison JD,Nuttley WM,Szilard RK,Brade AM,Glover JR,Rachubinski RA

更新日期：1992-12-01 00:00:00

abstract：:Chromosomal rearrangements are common in both clinical isolates and spontaneous mutants of Candida albicans. It appears that many of these rearrangements are caused by translocations around the major sequence repeat (MSR) that is present in all chromosomes except chromosome 3, suggesting that homologous recombination ...

journal_title：Molecular microbiology

authors： Ciudad T,Andaluz E,Steinberg-Neifach O,Lue NF,Gow NA,Calderone RA,Larriba G

更新日期：2004-08-01 00:00:00

abstract：:Recent studies examining the molecular mechanisms of isoniazid (INH) resistance in Mycobacterium tuberculosis have demonstrated that a significant percentage of drug-resistant strains are mutated in the katG gene which encodes a catalase-peroxidase, and the majority of these alterations are missense mutations which re...

journal_title：Molecular microbiology

authors： Rouse DA,DeVito JA,Li Z,Byer H,Morris SL

更新日期：1996-11-01 00:00:00

abstract：:Regulation of DNA replication in Bacillus subtilis involves a post-initiation mechanism which is subject to control by the Stringent System, an essential regulatory network, mediated by the alarmone, ppGpp. In detailed studies using DNA-DNA hybridization procedures, we have now shown that, following the induction of t...

journal_title：Molecular microbiology

authors： Levine A,Autret S,Séror SJ

更新日期：1995-01-01 00:00:00

abstract：:The cell envelope of mycobacteria is a complex multilaminar structure that protects the cell from stresses encountered in the environment, and plays an important role against the bactericidal activity of immune system cells. The outermost layer of the mycobacterial envelope typically contains species-specific glycolip...

journal_title：Molecular microbiology

authors： Sondén B,Kocíncová D,Deshayes C,Euphrasie D,Rhayat L,Laval F,Frehel C,Daffé M,Etienne G,Reyrat JM

更新日期：2005-10-01 00:00:00

abstract：:Cell morphogenesis is a complex process that depends on cytoskeleton and membrane organization, intracellular signalling and vesicular trafficking. The rod shape of the fission yeast Schizosaccharomyces pombe and the availability of powerful genetic tools make this species an excellent model to study cell morphology. ...

journal_title：Molecular microbiology

authors： Cadou A,Couturier A,Le Goff C,Soto T,Miklos I,Sipiczki M,Xie L,Paulson JR,Cansado J,Le Goff X

更新日期：2010-09-01 00:00:00

abstract：:Gram-negative bacteria, mitochondria, and chloroplasts all possess an outer membrane populated with a host of β-barrel outer-membrane proteins (βOMPs). These βOMPs play crucial roles in maintaining viability of their hosts, and therefore, it is essential to understand the biogenesis of this class of membrane proteins....

journal_title：Molecular microbiology

authors： Lundquist K,Billings E,Bi M,Wellnitz J,Noinaj N

更新日期：2020-12-13 00:00:00

abstract：:The genes of nicotine dehydrogenase (NDH) were identified, cloned and sequenced from the catabolic plasmid pAO1 of Arthrobacter nicotinovorans. In immediate proximity to this gene cluster is the beginning of the 6-hydroxy-L-niotine oxidase (6-HLNO) gene. NDH is composed of three subunits (A, B and C) of M(r) 30,011, 1...

journal_title：Molecular microbiology

authors： Grether-Beck S,Igloi GL,Pust S,Schilz E,Decker K,Brandsch R

更新日期：1994-09-01 00:00:00

abstract：:Ler, encoded by the locus of enterocyte effacement (LEE) of attaching and effacing (A/E) pathogens, induces the expression of LEE genes by counteracting the silencing exerted by H-NS. Ler expression is modulated by several global regulators, and is activated by GrlA, which is also LEE-encoded. Typical enteropathogenic...

journal_title：Molecular microbiology

authors： Bustamante VH,Villalba MI,García-Angulo VA,Vázquez A,Martínez LC,Jiménez R,Puente JL

更新日期：2011-10-01 00:00:00

abstract：:The DNA repeat region of fcrA76, the gene encoding a group A streptococcal Fc-binding protein, was subcloned in-frame into an Escherichia coli plasmid expression vector. The expressed protein product displayed the same Fc-binding properties as the full-length Fc-binding protein expressed from fcrA76. The affinity-puri...

journal_title：Molecular microbiology

authors： Heath DG,Boyle MD,Cleary PP

更新日期：1990-12-01 00:00:00

abstract：:Histidine kinases (HK) sense and transduce via phosphorylation events many intra- and extracellular signals in bacteria, archaea, slime moulds and plants. HK are also widespread in the fungal kingdom, but their precise roles in the regulation of physiological processes remain largely obscure. Expanding genomic resourc...

journal_title：Molecular microbiology

authors： Defosse TA,Sharma A,Mondal AK,Dugé de Bernonville T,Latgé JP,Calderone R,Giglioli-Guivarc'h N,Courdavault V,Clastre M,Papon N

更新日期：2015-03-01 00:00:00

abstract：:The ctaD gene encoding subunit I of the aa3-type cytochrome c oxidase from Rhodobacter sphaeroides has been cloned. The gene encodes a polypeptide of 565 residues which is highly homologous to the sequences of subunit I from other prokaryotic and eukaryotic sources, e.g. 51% identity with that from bovine, and 75% ide...

journal_title：Molecular microbiology

authors： Shapleigh JP,Gennis RB

更新日期：1992-03-01 00:00:00

abstract：:Mycobacterium tuberculosis (Mtb) is the causative agent of the human disease Tuberculosis, and remains a worldwide health threat responsible for ∼1.7 million deaths annually. During infection, Mtb prevents acidification of the engulfing phagosome, thus blocking endocytic progression and eventually leading to stable re...

journal_title：Molecular microbiology

authors： Mann FM,VanderVen BC,Peters RJ

更新日期：2011-03-01 00:00:00

abstract：:Multicopy dnaA(Ts) strains carrying the dnaA5 or dnaA46 allele are high-temperature resistant but are cold sensitive for colony formation. The DnaA5 and DnaA46 proteins both have an A184-->V change in the ATP binding motif of the protein, but they also have one additional mutation. The mutations were separated, and it...

journal_title：Molecular microbiology

authors： Nyborg M,Atlung T,Skovgaard O,Hansen FG

更新日期：2000-03-01 00:00:00

abstract：:Helicobacter pylori strains isolated from most patients with peptic ulcer disease and adenocarcinoma express the vacuolating toxin VacA and contain a pathogenicity island named cag. The cag pathogenicity island codes for more than 40 putative proteins with features similar to bacterial secretion systems. One of these ...

journal_title：Molecular microbiology

authors： Spohn G,Beier D,Rappuoli R,Scarlato V

更新日期：1997-10-01 00:00:00

abstract：:The newly sequenced genome of Streptomyces coelicolor is estimated to encode 7825 theoretical proteins. We have mapped approximately 10% of the theoretical proteome experimentally using two-dimensional gel electrophoresis and matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry. Pro...

journal_title：Molecular microbiology

authors： Hesketh AR,Chandra G,Shaw AD,Rowland JJ,Kell DB,Bibb MJ,Chater KF

更新日期：2002-11-01 00:00:00

abstract：:Anabaena variabilis ATCC 29413 fixes nitrogen in specialized cells called heterocysts using either a Mo-nitrogenase or a V-nitrogenase. V-nitrogenase structural genes, vnfDGK, as well as vnfEN form an operon with ava4025, located upstream of vnfDG that is repressed by fixed nitrogen and by Mo. The ava4025-vnfDGKEN ope...

journal_title：Molecular microbiology

authors： Pratte BS,Sheridan R,James JA,Thiel T

更新日期：2013-04-01 00:00:00

abstract：:Polyadenylation is a universal post-transcriptional modification involved in degradation and quality control of bacterial RNAs. In Escherichia coli, it is admitted that any accessible RNA 3' end can be tagged by a poly(A) tail for decay. However, we do not have yet an overall view of the population of polyadenylated m...

journal_title：Molecular microbiology

authors： Maes A,Gracia C,Hajnsdorf E,Régnier P

更新日期：2012-01-01 00:00:00

abstract：:We have identified gene fusions of polyamine biosynthetic enzymes S-adenosylmethionine decarboxylase (AdoMetDC, speD) and aminopropyltransferase (speE) orthologues in diverse bacterial phyla. Both domains are functionally active and we demonstrate the novel de novo synthesis of the triamine spermidine from the diamine...

journal_title：Molecular microbiology

authors： Green R,Hanfrey CC,Elliott KA,McCloskey DE,Wang X,Kanugula S,Pegg AE,Michael AJ

更新日期：2011-08-01 00:00:00

abstract：:Nodularia spumigena is a filamentous nitrogen-fixing cyanobacterium that forms toxic blooms in brackish water bodies worldwide. Spumigins are serine protease inhibitors reported from a single strain of N. spumigena isolated from the Baltic Sea. These linear tetrapeptides contain non-proteinogenic amino acids including...

journal_title：Molecular microbiology

authors： Fewer DP,Jokela J,Rouhiainen L,Wahlsten M,Koskenniemi K,Stal LJ,Sivonen K

更新日期：2009-09-01 00:00:00

abstract：:It has been hypothesized that the dinR gene product of Bacillus subtilis acts as a repressor of the SOS regulon by binding to DNA sequences located upstream of SOS genes, including dinR and recA. Following activation as a result of DNA damage, RecA is believed to catalyse DinR-autocleavage, thus derepressing the SOS r...

journal_title：Molecular microbiology

authors： Haijema BJ,van Sinderen D,Winterling K,Kooistra J,Venema G,Hamoen LW

更新日期：1996-10-01 00:00:00

abstract：:polY, a transcriptional regulatory gene in the polyoxin biosynthetic cluster of Streptomyces cacaoi, was analysed, and its deduced product (PolY) showed amino acid sequence homology to AfsR from Streptomyces coelicolor A3(2). PolY contains an OmpR-like DNA binding domain at its N-terminal and an ATPase domain in the m...

journal_title：Molecular microbiology

authors： Li R,Liu G,Xie Z,He X,Chen W,Deng Z,Tan H

更新日期：2010-01-01 00:00:00

abstract：:Photoregulation of pigmentation during complementary chromatic acclimation (CCA) is well studied in Fremyella diplosiphon; however, mechanistic insights into the CCA-associated morphological changes are still emerging. F. diplosiphon cells are rectangular under green light (GL), whereas cells are smaller and spherical...

journal_title：Molecular microbiology

authors： Singh SP,Montgomery BL

更新日期：2014-07-01 00:00:00

abstract：:The mechanisms of transcription repression and derepression in vivo are not fully understood. We have obtained evidence that begins to clarify the minimum requirements for counteracting nucleosomal repression in vivo. Location of the TATA element near the nucleosome dyad does not block RNA polymerase II transcription ...

journal_title：Molecular microbiology

authors： Moss DR,Laybourn PJ

更新日期：2000-06-01 00:00:00

abstract：:Pseudomonas syringae pv. tomato (Pst) strain DC3000 infects the model plants Arabidopsis thaliana and tomato, causing disease symptoms characterized by necrotic lesions surrounded by chlorosis. One mechanism used by Pst DC3000 to infect host plants is the type III protein secretion system, which is thought to deliver ...

journal_title：Molecular microbiology

authors： Zwiesler-Vollick J,Plovanich-Jones AE,Nomura K,Bandyopadhyay S,Joardar V,Kunkel BN,He SY

更新日期：2002-09-01 00:00:00