Bactericidal activity of magainin 2: use of lipopolysaccharide mutants.

Abstract:

:Salmonella typhimurium and a series of rough lipopolysaccharide mutants derived from it were used as target bacteria to examine the antimicrobial capacity of magainin 2. Magainin 2 demonstrated a dose-related bactericidal activity against the smooth parent strain and the series of lipopolysaccharide mutants. The lipopolysaccharide mutant series showed an ordered increase in sensitivity to the magainin 2 as the depth of the rough lesion in the lipopolysaccharide increased.

journal_name

Can J Microbiol

authors

Macias EA,Rana F,Blazyk J,Modrzakowski MC

doi

10.1139/m90-102

subject

Has Abstract

pub_date

1990-08-01 00:00:00

pages

582-4

issue

8

eissn

0008-4166

issn

1480-3275

journal_volume

36

pub_type

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