Abstract:
:Studies have shown that the maternal risk for Down syndrome (DS) may be modulated by alterations in folate metabolism. The aim of this study was to evaluate the influence of 12 genetic polymorphisms involved in folate metabolism on maternal risk for DS. In addition, we evaluated the impact of these polymorphisms on serum folate and plasma methylmalonic acid (MMA, an indicator of vitamin B
journal_name
Dis Markersjournal_title
Disease markersauthors
Zampieri BL,Biselli JM,Goloni-Bertollo EM,Vannucchi H,Carvalho VM,Cordeiro JA,Pavarino ECdoi
10.3233/DMA-2011-0869subject
Has Abstractpub_date
2012-01-01 00:00:00pages
73-81issue
2eissn
0278-0240issn
1875-8630pii
F200R02650112314journal_volume
32pub_type
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