MicroRNAs as components of regulatory networks controlling erythropoiesis.

abstract：:This review summarizes present knowledge on porcine platelets in vitro and recent studies on in vivo activation of platelets in the pig. There are certain differences compared to human platelets: Platelet aggregation and secretion cannot be achieved by epinephrine, and the arachidonate pathway seems poorly developed i...

journal_title：European journal of haematology

authors： Søfteland E,Framstad T,Thorsen T,Holmsen H

更新日期：1992-10-01 00:00:00

abstract：:During the period 1978-1982 in the three northernmost countries of Sweden all 143 patients with a registered diagnosis of chronic lymphocytic leukemia (CLL) were retrospectively analyzed. After re-evaluation, 122 cases remained in the study. The mean age was 71 years and the male/female ratio was 2.2:1. Sixty-one pati...

journal_title：European journal of haematology

authors： Erlanson M,Osterman B,Jonsson H,Lenner P

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVE:For transplantation of cord blood (CB) cells, it is important to select a CB sample that can reconstitute not only myelo-erythropoiesis but also lymphopoiesis in recipients. However, until now the reconstitution ability of CB samples has been assessed by colony forming unit-culture (CFU-C) assay or by simply ...

journal_title：European journal of haematology

authors： Kato M,Masuda K,Kakugawa K,Kawamoto H,Mugishima H,Katsura Y

更新日期：2008-02-01 00:00:00

abstract：:We previously reported an increased risk of monoclonal gammopathy of undetermined significance (MGUS) in first-degree relatives of MGUS and multiple myeloma patients. Here, we examine whether primary cytogenetic categories of myeloma differ between patients with and without a family history of MGUS or myeloma. We stud...

journal_title：European journal of haematology

authors： Greenberg AJ,Cousin M,Kumar S,Ketterling RP,Knudson RA,Larson D,Colby C,Scott C,Vachon CM,Rajkumar SV

更新日期：2013-09-01 00:00:00

abstract：:Haemoglobin (Hb) Hope [beta136(H14)Gly-->Asp(GGT-->GAT)] is one of the unstable haemoglobin variants of the beta-globin chain, which is demonstrated in people of various ethnic backgrounds. Here we report a Thai female patient with clinical thalassaemia intermedia since childhood. This patient had experienced neither ...

journal_title：European journal of haematology

authors： Sura T,Busabaratana M,Youngcharoen S,Wisedpanichkij R,Viprakasit V,Trachoo O

更新日期：2007-09-01 00:00:00

abstract：:The purpose of this study was to analyse the influence of the hospital size, measured as the number of annual patient enrolments in the Finnish Leukaemia Group trials in the period 1979-85, on response rate and survival after conventional chemotherapy for multiple myeloma. The 432 myeloma patients for this study were ...

journal_title：European journal of haematology

authors： Oivanen T,Kellokumpu-Lehtinen P,Koivisto AM,Koivunen E

更新日期：1999-10-01 00:00:00

abstract：:Upshaw-Schulman syndrome (USS) is due to severe congenital deficiency of von Willebrand factor (VWF)-cleaving protease ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 domains, nr 13) activity resulting in the presence of unusually large forms of VWF in the circulation, causing intravascular plat...

journal_title：European journal of haematology

authors： Rank CU,Kremer Hovinga J,Taleghani MM,Lämmle B,Gøtze JP,Nielsen OJ

更新日期：2014-02-01 00:00:00

abstract：:We studied 15 Sicilian subjects with Hb H disease correlating clinical examinations with hematological and molecular data. Seven different alpha-tha1 mutations were identified: four deletion types (--MED --CAL, -alpha3.7, -alpha4.2) and three nondeletion types (alpha(Ncol)alpha, alpha(Hph)alpha, alphaCSalpha). All the...

journal_title：European journal of haematology

authors： Mirabile E,Samperi P,Di Cataldo A,Poli A,La Spina M,Schilirò G

更新日期：2000-11-01 00:00:00

abstract：:Neutrophil gelatinase-associated lipocalin (NGAL) is a siderphore binding molecule present in the specific granules of neutrophils and induced in a variety of epithelial cells during inflammation. Its mouse orthologue, 24p3, is also an acute phase protein synthesized in the liver and adipose tissue during inflammation...

journal_title：European journal of haematology

authors： Klausen P,Niemann CU,Cowland JB,Krabbe K,Borregaard N

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Immune checkpoint inhibitors (CPI) are widely used in modern oncology and have improved the prognosis of lung cancer, malignant melanoma, and other malignancies. Unlike cytotoxic chemotherapy, drugs such as nivolumab, pembrolizumab, and ipilimumab are associated with immune-related adverse effects. We recent...

journal_title：European journal of haematology

authors： Tanios GE,Doley PB,Munker R

更新日期：2019-02-01 00:00:00

abstract：:A consecutive material of 111 untreated patients with non-Hodgkin's lymphoma was studied with respect to fraction of S-phase cells in blood mononuclear cells in relation to presence of monoclonal B cells in blood (MBCB). Fraction of S-phase cells was determined by flow cytometry and estimation of MBCB was performed by...

journal_title：European journal of haematology

authors： Lindh J,Jonsson H,Lenner P,Roos G

更新日期：1989-04-01 00:00:00

abstract：:Twenty-nine consecutive cases with a t(8;21)(q22;q22) in the bone marrow (BM) karyotype were retrospectively studied concerning clinical, morphological and cytogenetic data. All had been diagnosed as acute myeloid leukaemia (AML), 27 FAB subtype M2 and two M1, comprising 5% of all cytogenetically analysed AML during 1...

journal_title：European journal of haematology

authors： Billström R,Johansson B,Fioretos T,Garwicz S,Malm C,Zettervall O,Mitelman F

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the activation of clotting systems in patients with sickle cell disease (SCD) by measuring the plasma D-dimer level and to determine the effect of low-dose warfarin on D-dimer level during vaso-occlusive crisis. METHODS:Plasma D-dimer level was measured in 65 blood samples of 37 adult patients wi...

journal_title：European journal of haematology

authors： Ahmed S,Siddiqui AK,Iqbal U,Sison CP,Shahid RK,Sheth M,Patel DV,Russo LA

更新日期：2004-03-01 00:00:00

abstract：:We investigated whether depressed plasma antithrombin and protein C activity, considered as a specific finding of disseminated intravascular coagulation (DIC), is due to consumption coagulopathy in septic patients with DIC. An analysis of hemostatic parameters was performed in 139 septic patients (68 with DIC and 71 w...

journal_title：European journal of haematology

authors： Asakura H,Ontachi Y,Mizutani T,Kato M,Ito T,Saito M,Morishita E,Yamazaki M,Aoshima K,Takami A,Yoshida T,Suga Y,Miyamoto K,Nakao S

更新日期：2001-09-01 00:00:00

abstract：AIMS:Platelets retain cytoplasmic messenger RNA and are capable of protein biosynthesis. Several diseases are known to impact the platelet transcriptome but the effect of non-valvular atrial fibrillation (NVAF) on platelet RNA transcript is essentially unknown. The aim of this study was to evaluate the impact of NVAF o...

journal_title：European journal of haematology

authors： Wysokinski WE,Tafur A,Ammash N,Asirvatham SJ,Wu Y,Gosk-Bierska I,Grill DE,Slusser JP,Mruk J,McBane RD

更新日期：2017-06-01 00:00:00

abstract：:High mobility group box 1 protein (HMGB1), originally described as a non-histone, DNA binding protein, was recently identified as a late mediator of inflammation via its extracellular release from activated macrophages/monocytes. In the present study, we report that intracellular HMGB1 synergizes with a macrophage/mon...

journal_title：European journal of haematology

authors： Mouri F,Tsukada J,Mizobe T,Higashi T,Yoshida Y,Minami Y,Izumi H,Kominato Y,Kohno K,Tanaka Y

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To determine the financial and psycho-social impact of participation in clinical trials of patients with BCR/ABL-negative myeloproliferative neoplasms (MPN). METHODS:An international, observational cross-sectional study was performed in 143 consecutive MPN patients (51% myelofibrosis, 36% polycythemia vera, ...

journal_title：European journal of haematology

authors： Goel S,Paoli C,Iurlo A,Pereira A,Efficace F,Barbui T,Tefferi A,Vannucchi AM,Cervantes F

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:Interferon-alpha (IFNalpha) was the first effective pharmacologic treatment of hairy cell leukemia (HCL). Since 1990 purine analogs replaced IFNalpha because of higher rates of complete remission and an invariable disease recurrence after cessation of IFNalpha. However, there are only limited data about long-...

journal_title：European journal of haematology

authors： Benz R,Siciliano RD,Stussi G,Fehr J

更新日期：2009-03-01 00:00:00

abstract：:Human red blood cells (RBC) are heterogeneous with respect to their size; the physiological significance of this heterogeneity has not yet been fully elucidated. To further investigate this problem, some characteristics of human RBC fractionated according to their mean corpuscular volume (MCV) by counterflow centrifug...

journal_title：European journal of haematology

authors： Vaysse J,Gattegno L,Pilardeau P

更新日期：1992-02-01 00:00:00

abstract：:GM-CSF may induce pulmonary complications, such as dyspnea with temporary decreases in oxygen saturation described as first dose effect for higher dosages of intravenous rhGM-CSF. This study investigated possible pulmonary disturbances in adult de novo AML patients receiving yeast rhGM-CSF 24 h prior to chemotherapy u...

journal_title：European journal of haematology

authors： Zühlsdorf M,von Eiff M,Thomas M,Büchner T

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:We report an extension study of patients with essential thrombocythaemia (ET) in the Hungarian Myeloproliferative Neoplasm (HUMYPRON) Registry, which demonstrated that over 6 years anagrelide significantly decreased the number of patients experiencing minor arterial and minor venous thrombotic events (TEs) vs...

journal_title：European journal of haematology

authors： Kellner A,Dombi P,Illes A,Demeter J,Homor L,Ercsei I,Simon Z,Karadi E,Herczeg J,Gy Korom V,Gasztonyi Z,Szerafin L,Udvardy M,Egyed M

更新日期：2020-10-01 00:00:00

abstract：:We reviewed the indications for and the results of bone marrow examination (BME) from HIV-infected patients as an attempt to improve its diagnostic yield. One-hundred-and-eight bone marrow specimens from 90 patients during a 3-year period were examined. A cytological, histological and microbiological study was carried...

journal_title：European journal of haematology

authors： Ciaudo M,Doco-Lecompte T,Guettier C,d'Agay MF,David F,Rioual N,Buu-Hoi A,Molina JM,Kazatchkine M,Modai J

更新日期：1994-09-01 00:00:00

abstract：:The management of anticoagulant therapy (OAT) in patients with factor VII (FVII) deficiency is a very challenging clinical issue, as warfarin further reduces FVII levels, thus potentially increasing bleeding risk. On the other hand, the International Normalized Ratio test is misleading in such patients, as they do not...

journal_title：European journal of haematology

authors： Arletti L,Coluccio V,Romagnoli E,Luppi M,Marietta M

更新日期：2019-07-01 00:00:00

abstract：:A 32-year-old male presented with isolated neutropenia 6 months after allogeneic bone marrow transplantation for CML from his HLA-matched brother. The presence of granulocyte-specific IgM and IgG antibodies in the patient's serum indicated an immune-mediated basis for the neutropenia. A variety of manoeuvres to suppre...

journal_title：European journal of haematology

authors： Koeppler H,Goldman JM

更新日期：1988-08-01 00:00:00

abstract：INTRODUCTION:Primary and post-ET/PV myelofibrosis are myeloproliferative neoplasms harboring in most cases driving mutations in JAK2, CALR or MPL, and a variable number of additional mutations in other genes. Molecular analysis represents a powerful tool to guide prognosis and clinical management. Only about 10% of pat...

journal_title：European journal of haematology

authors： Mannina D,Gagelmann N,Badbaran A,Ditschkowski M,Bogdanov R,Robin M,Cassinat B,Heuser M,Shahswar R,Thol F,Beelen D,Kröger N

更新日期：2019-12-01 00:00:00

abstract：:Acute panmyelosis with myelofibrosis is a rare and aggressive form of acute myeloid leukemia. We describe a new case with a huge proliferation of megakaryocytes, blast cells and reticulin fibers. The patient was treated with zoledronate, a third-generation bisphosphonate, and a gradual recovery from pancytopenia was o...

journal_title：European journal of haematology

authors： Español I,Romagosa V,Berlanga J,Domingo A,Losa F,Heras L,Janáriz J

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVES:We sought to evaluate the effectiveness and safety of rivaroxaban vs apixaban in non-valvular atrial fibrillation (NVAF) patients with end-stage renal disease (ESRD) and/or receiving dialysis in routine practice. METHODS:Using US MarketScan claims data from January 1, 2014, to December 31, 2017, we identifi...

journal_title：European journal of haematology

authors： Miao B,Sood N,Bunz TJ,Coleman CI

更新日期：2020-04-01 00:00:00

abstract：:Type IIB is a special variant of von Willebrand's disease, characterized by an abnormal von Willebrand factor which shows an increased interaction with platelets. This interaction sometimes causes platelet aggregation and thrombocytopenia in vivo. It involves the glycoprotein-Ib (GPIb) receptor on platelets and corres...

journal_title：European journal of haematology

authors： Donnér M,Andersson AM,Kristoffersson AC,Nilsson IM,Dahlbäck B,Holmberg L

更新日期：1991-11-01 00:00:00

abstract：:A 1-yr-old Japanese male infant developed hepatitis-associated aplastic anemia (AA), and anti-thymocyte globulin (ATG) plus cyclosporine A (CsA) was administered without any appreciable effects. Laboratory examination of the patient's serum obtained before therapy revealed various autoantibodies, such as PA-IgG, anti-...

journal_title：European journal of haematology

authors： Takamatsu H,Yagasaki H,Takahashi Y,Hama A,Saikawa Y,Yachie A,Koizumi S,Kojima S,Nakao S

更新日期：2011-06-01 00:00:00

abstract：:The aim of the present study was to determine whether angelicin is able to increase the expression of gamma-globin genes in human erythroid cells. Angelicin is structurally related to psoralens, a well-known chemical class of photosensitizers used for their antiproliferative activity in treatment of different skin dis...

journal_title：European journal of haematology

authors： Lampronti I,Bianchi N,Borgatti M,Fibach E,Prus E,Gambari R

更新日期：2003-09-01 00:00:00