Abstract:
:Massive hemorrhage is the main cause of mortality and morbidity in trauma patients, and is one of the most important causes in any patient following major surgery. Conventional treatment consists of volume replacement, including the transfusion of blood products, so that tissue perfusion and oxygenation may be maintained. Associated hypothermia, acidosis and coagulopathy is a lethal triad. This review focuses on the latest therapeutic management of massive hemorrhage. The authors advocate the use of crystalloids as per protocol (controlled volumes) in order to achieve a systolic blood pressure of 85mmHg. The administration of the three blood products (red cells, plasma, and platelets) should be on a 1:1:1 basis. Where possible, this in turn should be guided by thromboelastography performed at point of care near the patient. Coagulopathy can occur early and late. With the exception of tranexamic acid, the cost-benefit relationships of the hemostatic agents, such as fibrinogen, prothrombin complex, and recombinant F VII, are subject to discussion.
journal_name
Med Intensivajournal_title
Medicina intensivaauthors
Fernández-Hinojosa E,Murillo-Cabezas F,Puppo-Moreno A,Leal-Noval SRdoi
10.1016/j.medin.2011.11.010subject
Has Abstractpub_date
2012-10-01 00:00:00pages
496-503issue
7eissn
0210-5691issn
1578-6749pii
S0210-5691(11)00317-2journal_volume
36pub_type
杂志文章,评审abstract:OBJECTIVE:to document possible complications related to the location of central venous catheter (CVC) tip in the right atrium (RA) in two medical-surgical intensive care units (ICU). DESIGN:An observational, retrospective study of critically ill patients. SETTING:two medical-surgical ICUs. PATIENTS:adult patients in...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2010.07.003
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:An evaluation is made of the hospital mortality predicting capacity of the main predictive scoring systems. DESIGN:A 2-year retrospective cohort study was carried out. SETTING:A third level ICU with surgical and medical patients. PATIENTS:All patients with multiorgan failure during the first day in the ICU...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2015.03.005
更新日期:2016-04-01 00:00:00
abstract::Acute liver failure with criteria of seriousness and alcoholic etiology is a picture of worldwide distribution, with an elevated mortality, of approximately 50%, that requires admission to the ICU. Acute serious alcoholic hepatitis is defined by a Maddrey score value > 32 and/or spontaneous encephalopathy. Together wi...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/s0210-5691(06)74556-9
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:To describe the factors associated to morbidity-mortality in pediatric patients with severe head injury (SHI). MATERIAL AND METHOD:A review was made of the patients admitted to the Pediatric Intensive Care Unit (PICU) with SHI between July 1983 and December 2009. RESULTS:Of the 389 patients with head injuri...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2011.02.006
更新日期:2011-08-01 00:00:00
abstract::Burned patients may need prolonged admissions in the Intensive Care Service, both for initial care and for the pre and postoperative treatment of the multiple surgeries they require. The initial resuscitation of critically burned patients requires adequate monitoring to calculate the fluid therapy necessary to repleni...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2019.07.005
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:Analyze the utility and safety of MARS therapy applied with the CRRT monitor. DESIGN:Prospective study of cohorts. SCOPE:Polyvalent ICU in tertiary university hospital with hepatic transplantation program. PATIENTS:Thirty one patients: 9 (22.6%) with acute liver failure (ALF) (1 hepatic surgery, 1 primary ...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/s0210-5691(07)74841-6
更新日期:2007-10-01 00:00:00
abstract::The specialty of Intensive Care Medicine was established over twenty years ago in Spain as part of the MIR (Resident training) system. The European Union allows for free circulation of its workers and the multilateral recognition of their university degrees as well as their postgraduate training. Unfortunately, our sp...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2010.11.002
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To determine the clinical characteristics and prognostic factors of patients with severe sepsis/septic shock admitted to the Intensive Care Unit of Donostia University Hospital (Guipuzcoa, Spain). DESIGN:A prospective, observational study was carried out during a consecutive 6-year period (1st February 2008-...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2015.01.006
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To analyze the current evidence on glycemic control with insulin therapy in the critically ill. RECENT FINDINGS:Stress hyperglycemia in critically ill patients has been associated with increased morbidity and mortality. Furthermore, current evidence suggests that glucose variability has a predictive value fo...
journal_title:Medicina intensiva
pub_type: 杂志文章,评审
doi:10.1016/j.medin.2009.10.003
更新日期:2010-05-01 00:00:00
abstract::Tuberculosis miliar is a very rare complication of bacillus Calmette-Guérin (BCG) immunotherapy that is associated to high mortality. Thus, early diagnosis and treatment is essential. At present, there is a polymerase chain reaction technique (PCR) which is a rapid diagnostic method with elevated sensitivity. Treatmen...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/s0210-5691(06)74485-0
更新日期:2006-04-01 00:00:00
abstract::Maintaining organ viability from extraction to transplantation is crucial to ensure the function and survival of the graft. In recent years, maintaining organ viability has become more challenging because the shortage of donors has led to broader criteria for donor acceptability and consequently to organs with greater...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/S0210-5691(09)72196-5
更新日期:2009-08-01 00:00:00
abstract::Second level therapeutic maneuvres for controlling intracranial hypertension (ICH) proposed by the European Brain Injury Consortium and the American Association of Neurological Surgeons include barbiturates, moderate hypothermia and more recently the decompressive craniectomy (DC).In most patients, ICP can be maintain...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2010.09.011
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:To identify factors related to mortality in adult trauma patients, analyzing the clinical, epidemiological and therapeutic characteristics at the pre-hospital levels, in the Emergency Care Department and in Intensive Care. DESIGN:A retrospective, longitudinal descriptive study was carried out. Statistical an...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2014.06.004
更新日期:2015-10-01 00:00:00
abstract::This article is based on the strategic reflection and discussion that took place on occasion of the first conference on innovation and technology transfer in the health sciences organized by the REGIC-ENS-FENIN-SEMICYUC and held in Madrid in the Instituto de Salud Carlos III on May 7th, 2013, with the aim of promoting...
journal_title:Medicina intensiva
pub_type:
doi:10.1016/j.medin.2014.04.012
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To analyze the profile, incidence of life support therapy limitation (LSTL) and donation potential in neurocritical patients. STUDY DESIGN:A multicenter prospective study was carried out. SETTING:Nine hospitals authorized for organ harvesting for transplantation. PATIENTS:All patients consecutively admitte...
journal_title:Medicina intensiva
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medin.2014.07.010
更新日期:2015-08-01 00:00:00
abstract::Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by a newly emergent coronavirus, that was first recognized in Wuhan, China, in December 2019. Currently, the World Health Organization (WHO) has defined the infection as a global pandemic and there is a health and social emergency for the mana...
journal_title:Medicina intensiva
pub_type: 共识发展会议,杂志文章,实务指引
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更新日期:2020-10-01 00:00:00
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journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2013.08.006
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:To determine the results of the implementation of a protocol in an intensive care unit (ICU) referred to critically ill patients requiring a prolonged artificial airway. DESIGN:A prospective, observational cohort study was carried out. INTERVENTION:Management strategies were established on the airway by end...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2012.07.003
更新日期:2013-08-01 00:00:00
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journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2015.09.001
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To assess the impact of gender upon the prognosis and medical care in a regional acute ST-elevation myocardial infarction management network. DESIGN:An observational study was made of consecutive patients entered in a prospective database. SCOPE:The Catalan acute ST-elevation myocardial infarction managemen...
journal_title:Medicina intensiva
pub_type: 杂志文章,多中心研究
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更新日期:2017-03-01 00:00:00
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journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2014.02.006
更新日期:2014-12-01 00:00:00
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journal_title:Medicina intensiva
pub_type: 杂志文章,评审
doi:10.1016/j.medin.2009.11.010
更新日期:2010-10-01 00:00:00
abstract::The current COVID-19 pandemic has rendered up to 15% of patients under mechanical ventilation. Because the subsequent tracheotomy is a frequent procedure, the three societies mostly involved (SEMICYUC, SEDAR and SEORL-CCC) have setup a consensus paper that offers an overview about indications and contraindications of ...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2020.05.002
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:To determine the epidemiological and clinical characteristics of the patients with severe sepsis/septic shock admitted to the ICU of Donostia Hospital (Guipuzcoa, Spain), analyzing the prognostic factors and comparing them with the existing data at national level. DESIGN:A prospective observational study was...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2011.10.006
更新日期:2012-05-01 00:00:00
abstract::Both acute myocardial infarction and pulmonary thromboembolism are responsible for a great number of cardiac arrests. Both present high rates of mortality. Thrombolysis has proved to be an effective treatment for acute myocardial infarction and pulmonary thromboembolism with shock. It would be worth considering whethe...
journal_title:Medicina intensiva
pub_type: 杂志文章,评审
doi:10.1016/s0210-5691(06)74470-9
更新日期:2006-03-01 00:00:00
abstract::The use of neuromuscular blockers (NMB) is a frequent practice in Intensive Care Units. However most of the experience with the use of these agents come from the operating room used to deal with patients with different characteristics from those admitted in the ICU. Recent advances on neuromonitoring and the commercia...
journal_title:Medicina intensiva
pub_type: 杂志文章,评审
doi:
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:To detect donor characteristics related to graft function after orthotopic liver transplantation (OLT). DESIGN:Retrospective cohort study. CONTEXT:Polyvalent intensive care unit. PATIENTS:145 liver transplant recipients and their respective donors. INTERVENTIONS:None. MAIN VARIABLES OF INTEREST:In donors...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/s0210-5691(08)75708-5
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:To assess the efficacy and safety of a treatment with clopidogrel when associated or not to the treatment with tirofiban and aspirin for high-risk non-ST segment elevation myocardial infarction (non-STEMI), without early angioplasty. SETTING:Intensive Care and Coronary Unit (ICCU), in a center with no Hemody...
journal_title:Medicina intensiva
pub_type: 临床试验,杂志文章
doi:10.1016/s0210-5691(07)74801-5
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVE:To analyze the efficacy of negative fluid balance in hypoxemic patients with an elevated extravascular lung water index (EVLWI). DESIGN:A retrospective observational study was made. SETTING:Intensive Care Unit of Virgen de las Nieves Hospital (Spain). PARTICIPANTS:Forty-four patients participated in the st...
journal_title:Medicina intensiva
pub_type: 杂志文章
doi:10.1016/j.medin.2014.07.008
更新日期:2015-08-01 00:00:00
abstract::In 1994, an American-European Consensus Conference (AECC) formalized the criteria for the diagnosis of the acute respiratory distress syndrome (ARDS). Although that definition is simple to apply in the clinical setting, it has been challenged over the years in several studies since the assessment of the oxygenation de...
journal_title:Medicina intensiva
pub_type: 共识发展会议,杂志文章
doi:10.1016/j.medin.2012.08.010
更新日期:2012-11-01 00:00:00