Abstract：
:A large number of published overview and original articles provide evidence and declare the need for immediate, appropriate preventive lifestyle measures to prevent the development of dementia and Alzheimer's disease (AD). However, despite this, there are great difficulties in drafting effective guidelines in this field. This is mainly due to a lack of not only (comparable) randomized controlled trials but also a lack of homogeneous measures of type and degree of managed risk. Several risk factors for dementia are non-modifiable, such as genes and age. Factors related to lifestyle habits and vascular risk factors are classified as modifiable risk factors. While waiting for effective drug therapies and first-level evidence data, geriatricians, general practitioners, neurologists, and health professionals should be encouraged to improve early diagnosis of cognitive impairment and activate control strategies against vascular disease and unhealthy lifestyle habits.
journal_name
Z Gerontol Geriatrjournal_title
Zeitschrift fur Gerontologie und Geriatrieauthors
Polidori MC,Pientka Ldoi
10.1007/s00391-011-0263-5subject
Has Abstractpub_date
2012-01-01 00:00:00pages
7-10issue
1eissn
0948-6704issn
1435-1269journal_volume
45pub_type
杂志文章abstract：:An enhanced inflammatory state - i.e. "inflammatory/pathogen burden" - in the elderly on the one hand results from physiological immunosenescence and on the other hand is modified by the individual immune history: the latter is determined by sequential infectious/pathogenic events ("multiple hits"). Immunosenescence m...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-007-0486-7
更新日期：2007-10-01 00:00:00
abstract：:The obvious increase of human age even up to above one hundred years in nearly all civilised countries leeds the autor to discuss the following actual gerontologic problems: the needs for further splitting of categories of high age, the reasons for the rapid increase of the oldest-old group and the predicted "mushroom...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Composition of staff and therapeutic offers of day-hospitals principally are identical with those of geriatric hospitals. But there are peculiarities in their working: They offer a well balanced combination of somato-, physio-, psycho- and sociotherapy which individually must be planned, perpetually controlled and if ...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：BACKGROUND:Aged skin is the sum of chronological und UV-induced aging. Light-exposed skin is unattractive, with irregular pigmentation, roughness und scaliness. The skin is often dry and itches. METHODS:The present paper provides an overview of diseases of aging skin and describes how to prevent or reduce disease by p...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-014-0670-5
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:Ambulatory geriatric rehabilitation (AGR) is a prevention program for multimorbid patients with the contractual agreement to prevent the need for care and hospital admissions and to promote self-sufficiency. It provides an opportunity to reduce the prevalence of polypharmacy and to discontinue potentially in...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-019-01589-1
更新日期：2020-08-01 00:00:00
abstract：:The NaCl content of the culture medium of human fibroblasts (WI-38) was elevated from 0.12 M to 0.23 M. Previously it had been shown that exposure of fibroblasts to such high NaCl conditions resulted in a rise of both glycolysis and respiration ("energetic stress"), mainly due to increased demands of energy for active...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s003910170014
更新日期：2001-12-01 00:00:00
abstract：BACKGROUND:Impairment of central auditory processing is a well-known symptom of neurodegenerative dementia; however, whilst numerous studies have examined verbal processing impairment, to date few have attempted to describe impairments of non-verbal, environmental sound recognition in patients with dementia. As these i...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-017-1216-4
更新日期：2018-07-01 00:00:00
abstract：:Heating of food induces the formation of Maillard reaction products (MRPs) caused by the reaction of reducing sugars with proteins or amino acids. Analogous reactions occur in the human body, eventually forming "Advanced Glycation Endproducts" (AGEs). AGEs accumulate in aging tissues accelerating degenerative-inflamma...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-005-0263-4
更新日期：2005-10-01 00:00:00
abstract：:Geriatric patients with non-valvular atrial fibrillation (AF) are increasingly being treated with novel oral anticoagulants (NOAC) to prevent ischemic stroke. This article highlights the outcome of an expert meeting on the practical use of NOAC in elderly patients. An interdisciplinary group of experts discussed the c...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-016-1027-z
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:World War II (WWII) is probably the most distressing and fatal historical event in Europe's recent past. Research on mental and physical health sequelae of these traumatic experiences from WWII has only started recently. OBJECTIVES:An overview on the findings from several population-based studies investigat...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-014-0624-y
更新日期：2014-04-01 00:00:00
abstract：:The mortality in elderly patients over the age of 80 years with peptic ulcers in the case of complications, such as bleeding and perforation is higher than in the general population. Duodenal ulcers are associated with Helicobacter pylori infections in 90% of cases and in 70% of gastric ulcers. The treatment of elderl...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-017-1190-x
更新日期：2017-02-01 00:00:00
abstract：:The degree of Objective Health Burden (OHB) is an expert assessment of the impairment caused by somatic illnesses. It allows an overall clinical rating of the severity of a patient's somatic condition, considering all available information, not only the content or number of diagnoses. The rating on a five point scale ...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s003910050111
更新日期：1999-08-01 00:00:00
abstract：BACKGROUND:Which deficits in cognitive performance indicate the onset of a pathological deterioration process in older persons? AIM AND OBJECTIVES:Based on an established dementia screening test in elderly adults, a differentiation can be made between healthy cognitive performance and the onset of pathological deficit...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-017-1263-x
更新日期：2018-04-01 00:00:00
abstract：:This paper reports a qualitative study in which the aim was to examine older peoples' beliefs and risk perceptions regarding the use of innovative health technologies in end-of-life care and to relate these beliefs to their ideas about 'natural death'. Pictures, story boards and media extracts were used during intervi...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-003-0166-1
更新日期：2003-10-01 00:00:00
abstract：:The aging of the Italian population is an emerging public health priority. In 2025 Italy is expected to have the highest world median age with nearly half of the population over 50 years old. To avoid an unbearable burden of disease and disability on future generations, we must identify areas for intensive disease and...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s003910050139
更新日期：1999-12-01 00:00:00
abstract：:The results of the determination of hematologic values from 262 men and 242 women, participants of an aging study and half of each group 44.4 +/- 0.9 and 63.0 +/- 0.9 (men) and 44.4 +/- 0.9 and 62.8 +/- 0.8 years old (women), respectively, are compared. In men, one analyte (hemoglobin decreasing) and four indices show...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s003910170062
更新日期：2001-06-01 00:00:00
abstract：BACKGROUND:Over the course of the demographic transition with an aging and shrinking work force, work participation of older employees becomes more and more important. Earlier investigations found social groups to be different in work-related and individual aspects, which were shown to be associated with motivation for...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-018-1450-4
更新日期：2019-02-01 00:00:00
abstract：:National and international data networks for data transfer and communication are playing an increasingly important role in science and medicine. These networks already exist on a regional, national and international scale. The biggest international network, the Internet, offers more than 300 sites referring to "aging"...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：:As part of a research project, a behavior therapy-oriented cognitive training program, designed to improve the cognitive ability of middle-aged employees (50 to 59 years), was implemented and evaluated. The goal of the training program was to analyze the cognitive, affective and behavior-related conditions of memory d...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-009-0044-6
更新日期：2009-12-01 00:00:00
abstract：:The aim of this study is to bring into focus the living conditions of the older adults in Turkey by using quality of life (QoL) criteria through which to highlight dimensions relating to their QoL status in comparison to other age cohorts. Are there specific QoL issues among older adults that would indicate that they ...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-013-0502-z
更新日期：2013-12-01 00:00:00
abstract：AIM:The goal of this study was to perform a structured analysis of the treatment quality and acute complications of geriatric patients with diabetes mellitus (DM) cared for by nursing services and nursing home facilities. Secondly, structural problems and potentials for improvement in the care of multimorbid older peop...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-014-0626-9
更新日期：2015-04-01 00:00:00
abstract：:The prevalence of chronic pain increases with age. The awareness of pain in geriatric patients is more difficult than in younger people because of various reasons. The occupational groups of the geriatric team might be different in respect of discerning symptoms of pain. 126 geriatric patients were enrolled in this st...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s003910170039
更新日期：2001-10-01 00:00:00
abstract：BACKGROUND:The hierarchical assessment of balance and mobility (HABAM) is an internationally established clinical mobility test which has good psychometric properties, allows an easy assessment of mobility and the graphical illustration of change over time in geriatric patients. The aims of this study were the translat...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-016-1026-0
更新日期：2016-07-01 00:00:00
abstract：:The purpose of this study was to validate the German translation of the originally English Fullerton Advanced Balance Scale (FAB-D). The 10-item test battery is a performance-based measure that addresses the multiple dimensions of balance. The German FAB-D using a forward-backward procedure was examined by a sample of...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-011-0236-8
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Even though the effects of cultural activities on active and positive ageing have been extensively examined, spatial aspects have hardly been considered by research in this field. OBJECTIVES:Instead of understanding active ageing as a result of cultural education, this article focuses on practices of (activ...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章,评审
doi：10.1007/s00391-020-01751-0
更新日期：2020-08-01 00:00:00
abstract：:The existence of a so-called "vitauct process" is discussed by means of the glucocorticoid-induced stimulation of tyrosine aminotransferase activity. Own experiments show that the highest possible stimulation of the enzyme by cortisol and stress in the liver of old Wistar rats is not lower than in young-adult animals....
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：:The prognosis for patients with diastolic heart failure--heart failure with preserved ejection fraction--has not improved in the last few decades despite improvement of prognosis for all patients with heart failure. Diastolic dysfunction is a typical finding in elderly patients with heart failure. The diagnostic proce...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-012-0345-z
更新日期：2013-01-01 00:00:00
abstract：:For a period of 3 consecutive years, all fall events were prospectively recorded in geriatric hospital in-patients by using a standardized protocol. The incidence was 9.1 fall events/1000 hospital days in 5946 patients, and 41.0/1000 hospital days in 1015 patients (17.0%) who actually had falls. The fall rate varied b...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-004-0204-7
更新日期：2004-02-01 00:00:00
abstract：BACKGROUND:Dry mouth is a frequently occurrence in elderly people and causes numerous clinical and social problems. OBJECTIVE:To investigate the quality of life in geriatric patients living in nursing homes depending on the subjective sensation of dry mouth and associated oral parameters. MATERIAL AND METHODS:A total...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：10.1007/s00391-015-0968-y
更新日期：2017-02-01 00:00:00
abstract：:While hemiendoprothesis has been established in the treatment of hip fractures of aged people because of less operative trauma, better effectiveness and satisfying functionality, surgical management of trochanteric fractures is still in discussion. In our study, we found no severe difference of living conditions or mo...
journal_title：Zeitschrift fur Gerontologie und Geriatrie
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
