Abstract:
INTRODUCTION:The aim of this study was to assess the malignancy rate in patients with Hürthle cell metaplasia (HCM) on fine-needle aspiration biopsy (FNAB). METHODS:The pathology results of patients with benign colloid (BC) and HCM on FNAB were compared using a prospective database. RESULTS:One hundred fifty-three (65%) patients had BC on FNAB, and 82 (35%) had HCM. The mean nodule size was similar in both groups (25 ± 2 mm vs 26 mm ± 2 mm, P = .83). Malignancy was identified on the final pathology report in 21 (14%) versus 13 (16%) patients in the BC and HCM groups, respectively (P = .66). Of the patients with malignancy, the tumor was determined as microcarcinoma in 76% in the BC groups versus 85% in the HCM group (P = .48) and as incidental in 71% versus 85% (P = .39). CONCLUSIONS:A result of HCM on FNAB carries a similar rate of malignancy as BC and should not be treated differently. Most of the malignancies found were incidental microcarcinomas.
journal_name
Am J Surgjournal_title
American journal of surgeryauthors
Hudak K,Mazeh H,Sippel RS,Chen Hdoi
10.1016/j.amjsurg.2011.09.019subject
Has Abstractpub_date
2012-03-01 00:00:00pages
287-90; discussion 290-1issue
3eissn
0002-9610issn
1879-1883pii
S0002-9610(11)00746-Xjournal_volume
203pub_type
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