Parathyroid hormone messenger ribonucleic acid in the rat hypothalamus.

Abstract:

:Polyadenylated RNA, extracted from rat hypothalami, cross-hybridized with a RNA probe complementary in sequence to rat PTH (rPTH) messenger RNA (mRNA). Amplification of complementary DNA (cDNA) by the polymerase chain reaction also demonstrated the presence of rPTH mRNA in the rat hypothalamus and parathyroid gland. rPTH mRNA was localized by in situ hybridization in the paraventricular and supraoptic nuclei of the rat hypothalamus. These results demonstrate the expression of the PTH gene in the central nervous system of the rat in areas which suggest roles for PTH in neuroendocrine function.

journal_name

Endocrinology

journal_title

Endocrinology

authors

Fraser RA,Kronenberg HM,Pang PK,Harvey S

doi

10.1210/endo-127-5-2517

subject

Has Abstract

pub_date

1990-11-01 00:00:00

pages

2517-22

issue

5

eissn

0013-7227

issn

1945-7170

journal_volume

127

pub_type

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