Abstract:
BACKGROUND:Electrogram fractionation can result when multiple groups of cardiac cells are excited asynchronously within the recording region of a mapping electrode. The spatial resolution of an electrode thus plays an important role in mapping complex rhythms. METHODS:We used a computational model, validated against experimental measurements in vitro, to determine how spatial resolution is affected by electrode diameter, electrode length, interelectrode distance (in the case of bipolar recordings), and height of the electrode above a dipole current source. RESULTS:We found that increases in all these quantities caused progressive degradation in two independent measures of spatial resolution, with the strongest effect being due to changes in height above the tissue. CONCLUSION:Our calculations suggest that if electrodes could be constructed to have negligible dimensions compared with those in use today, we would increase resolution by about one order of magnitude at most.
journal_name
Coron Artery Disjournal_title
Coronary artery diseaseauthors
Stinnett-Donnelly JM,Thompson N,Habel N,Petrov-Kondratov V,Correa de Sa DD,Bates JH,Spector PSdoi
10.1097/MCA.0b013e3283507a9bsubject
Has Abstractpub_date
2012-03-01 00:00:00pages
126-32issue
2eissn
0954-6928issn
1473-5830journal_volume
23pub_type
杂志文章abstract:BACKGROUND:The association of adipocyte-derived proteins, adiponectin and leptin, with the degree of coronary atherosclerosis has not been not been well elucidated. This study aimed to determine the relationship between serum adiponectin and leptin with the presence and degree of coronary atherosclerosis. METHODS:Seve...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e3283452431
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:The aim of this study was to identify psychosocial variables that, in addition to known medical factors, predict the long-term outcome after a first myocardial infarction. PATIENTS AND METHODS:The study population consisted of 222 men aged 30-60 years who entered an inpatient rehabilitation program a mean o...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199502000-00009
更新日期:1995-02-01 00:00:00
abstract:BACKGROUND:We report on 10 patients with Kawasaki disease and thrombocytopenia who were found to have a high incidence of coronary artery aneurysm and acute myocardial infarction. The clinical features of these patients, the cause of their thrombocytopenia and the relationship between cardiovascular pathology and throm...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:Restenosis after coronary angioplasty is considered to be caused mainly by increased migration and proliferation of smooth muscle cells (SMC). The concept of local, site-specific delivery of pharmacologic therapies has opened the door for new, high-dose drug regimes. METHODS AND RESULTS:SMC were isolated by...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199703000-00011
更新日期:1997-03-01 00:00:00
abstract::Potentially hazardous short ischemic episodes increase the tolerance of myocardium to ischemia paradoxically. This condition decreases the infarct area markedly caused by a longer duration of coronary occlusion. This phenomenon is known as 'ischemic preconditioning' and its powerful cardioprotective effect has been sh...
journal_title:Coronary artery disease
pub_type: 杂志文章,评审
doi:10.1097/00019501-200605000-00013
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:The optimal timing of angiography and percutaneous coronary intervention (PCI) in patients with non-ST elevation acute coronary syndromes (NSTEACS) remains uncertain. We sought to assess clinical characteristics and outcomes of patients in real-world contemporary practice who have early versus delayed PCI fo...
journal_title:Coronary artery disease
pub_type: 杂志文章,多中心研究
doi:10.1097/MCA.0000000000000374
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Circulating leukocytes are recruited at atherosclerotic sites through a family of adhesion molecules. Circulating forms of adhesion molecules in peripheral blood can be quantified now. OBJECTIVE:To evaluate the relationship between circulating adhesion molecules and severity of coronary atherosclerosis. ME...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200002000-00013
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:An association between early repolarization and ventricular fibrillation has recently been reported in patients with vasospastic angina (VSA). However, no studies have clarified whether the presence of early repolarization can predict VSA. METHODS:Participants comprised 286 patients (136 males) with clinica...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000983
更新日期:2020-11-13 00:00:00
abstract:OBJECTIVE:In response to the growing use of imaging-based cardiac stress tests in the evaluation of stable ischemic heart disease, professional societies have developed appropriate use criteria (AUC). AUC will soon be linked to reimbursement of advanced diagnostic imaging for Medicare beneficiaries via Clinical Decisio...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000928
更新日期:2020-08-13 00:00:00
abstract:BACKGROUND:The efficacy of thrombolytic therapy might be influenced by changes in the hemodynamic status. The aim of the study was to examine whether changes in perfusion pressure could affect the time to reflow in an in-vitro model. METHODS:The in-vitro flow system comprised flexible plastic tubes that enclosed a blo...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199809010-00007
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:We and others have demonstrated that administration of thrombolytic agents causes the generation of thrombosis-promoting agents. At present, we have studied whether formation in vivo of excessive amounts of plasmin is responsible for the activation of coagulation in patients treated with recombinant tissue-t...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-199304000-00009
更新日期:1993-04-01 00:00:00
abstract:BACKGROUND:The cause for discrepancy in the clinical presentation and outcome of coronary artery disease (CAD) between men and women is not established. Different prevalences of risk factors or specific sex-related atherosclerotic aspects have been advocated as possible explanations. We investigated coronary plaque mor...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000522
更新日期:2017-09-01 00:00:00
abstract::Chronic total occlusions (CTOs) are routinely encountered during coronary angiography, but subsequent revascularization rates are low. This has likely been driven by a historical belief that there is minimal clinical benefit and poor success rates with a percutaneous coronary intervention (PCI). However, in the curren...
journal_title:Coronary artery disease
pub_type: 杂志文章,评审
doi:10.1097/MCA.0000000000000490
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:To examine the contribution of six cardiovascular polymorphisms to the occurrence of a first event of ischemic heart disease (IHD) in a primary care population with a high prevalence of hypertension. Furthermore, we specified the data for sex and age. METHODS:In this cross sectional case-control study, patie...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e328330d541
更新日期:2009-12-01 00:00:00
abstract::ADP plays a pivotal role in localized platelet activation and recruitment, and, with that, in the maintenance of thrombus integrity, making it a suitable target for the control of intravascular thrombosis. The limited distribution of one of its receptors, the P2Y12 receptor, primarily to platelets makes it an especial...
journal_title:Coronary artery disease
pub_type: 杂志文章,评审
doi:10.1097/MCA.0b013e3283564930
更新日期:2012-09-01 00:00:00
abstract::The phenomenon of myocardial stunning has been observed in all animal species studied. The possible occurrence of myocardial stunning in man has been demonstrated after either regional ischemia (such as exercise-induced angina, vasospastic or unstable angina) or after global ischemia (i.e., after cardioplegic arrest d...
journal_title:Coronary artery disease
pub_type: 杂志文章,评审
doi:10.1097/00019501-200108000-00004
更新日期:2001-08-01 00:00:00
abstract::Optical coherence tomography (OCT) is the current state-of-the-art intracoronary imaging modality that allows visualization of detailed morphological characteristics of both atherosclerotic plaque and stent. So far, three expert review documents have been released for standardization of OCT image analysis. In the real...
journal_title:Coronary artery disease
pub_type: 杂志文章,评审
doi:10.1097/MCA.0000000000000072
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVE:Ga-NOTA-RGD PET is a newly developed molecular imaging for angiogenesis. In this study, Ga-NOTA-RGD PET was used to investigate imaging characteristics in a rat myocardial infarction (MI) model and to monitor the efficacy of an angiogenesis induction therapy. MATERIALS AND METHODS:Ga-NOTA-RGD PET was perform...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e3283608c32
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Diabetes is a strong predictor of a poor outcome after coronary artery bypass grafting (CABG). The prevalence of prediabetes and its impact on the prognosis after CABG is not well described. In this study, we evaluated the prevalence and prognostic impact of the different states of abnormal glucose regulatio...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e3283645c94
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Diabetic patients show an increased incidence of restenosis after coronary angioplasty than non-diabetic patients. This may be because of differences in the mechanism of lumen gain during coronary revascularization in this population cohort. DESIGN:This study analyses the mechanism of lumen gain during coro...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200208000-00003
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:The Cardiac Health Profile (CHP) is a new questionnaire for assessing health-related quality of life of patients with cardiovascular diseases. It consists of three parts assessed as follows: the degree of angina pectoris (the CCS scale), the quality of life and subjective scoring of psychosocial 'cost-benefi...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:Acute kidney injury (AKI) and anemia have been extensively studied in ST-elevation myocardial infarction (STEMI), yet the precise nature of their reciprocal relationship has not been elucidated in STEMI patients. METHODS:We performed a retrospective analysis of 2096 consecutive patients admitted for STEMI b...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000973
更新日期:2020-10-13 00:00:00
abstract:OBJECTIVE:To investigate the predictive value of the PRECISE-DAPT score for the development of arrhythmias in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. METHOD:A total of 706 patients with a diagnosis of ST-segment elevation myocardial infarction who...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000788
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Both intravascular ultrasound and optical coherence tomography have been purported to accurately detect and characterize coronary atherosclerotic plaque composition. The aim of our study was to directly compare the reproducibility and diagnostic accuracy of optical coherence tomography and intravascular ultr...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/00019501-200608000-00005
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVES:Although the relationship between atherosclerosis and inflammatory cells has been recognized in recent years, the effect of interleukin-6 (IL-6) genetic variants associated with atherosclerosis is still controversial. Therefore, we investigated the association between IL-6 polymorphism and levels of IL-6 in ...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e3282f27bf7
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:We hypothesized that an increase in plasminogen activator inhibitor 1 (PAI-1) might reduce low-density lipoprotein (LDL) particle size in conjunction with triglyceride (TG) metabolism disorder, resulting in an increased risk of atherosclerotic cardiovascular disease (ASCVD). METHODS:This study was carried o...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0000000000000521
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:Limited data exist about the prognostic significance of new-onset atrial fibrillation (AF) after contemporary primary percutaneous coronary intervention (pPCI). The objective of this study was to identify the incidence and predictors of new-onset AF and associated adverse 30-day outcomes in AF patients who u...
journal_title:Coronary artery disease
pub_type: 临床试验,杂志文章
doi:10.1097/MCA.0b013e32834df552
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Coronary artery ectasia is defined as localized or diffuse dilation of the coronary arteries exceeding the 1.5-fold of normal adjacent segment. Scarce data are available about the role of inflammation in coronary artery ectasia. In the present study, we aimed to evaluate the expression of CD11b and CD45 adhe...
journal_title:Coronary artery disease
pub_type: 杂志文章
doi:10.1097/MCA.0b013e32801104d4
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVES:This Perspective reviews the results of early and contemporary studies evaluating the safety and efficacy of coronary revascularization in patients with diabetes. It also addresses the implications of some of the data in the Bypass Angioplasty Revascularization Investigation in type 2 diabetes (BARI 2D) tria...
journal_title:Coronary artery disease
pub_type: 杂志文章,评审
doi:10.1097/MCA.0b013e3283383ebe
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:The transradial approach has gained increasing popularity for elective percutaneous coronary intervention. However, the safety and feasibility of transradial coronary intervention (TRI) in acute myocardial infarction (AMI) remains uncertain. Hence, a meta-analysis of randomized trials was performed to compar...
journal_title:Coronary artery disease
pub_type: 杂志文章,meta分析
doi:10.1097/MCA.0b013e3283526a9d
更新日期:2012-06-01 00:00:00