Abstract:
:Despite many recent advances in the past 40 years in the understanding of pain mechanisms, and in pain diagnosis and management, considerable gaps in knowledge remain, with chronic pain present in epidemic proportions in most countries. It is often unrelieved and is associated with significant socioeconomic burdens. Several opportunities and approaches to address this crisis are identified in the present article. Most crucial is the need to increase pain awareness, enhance pain education, improve access to pain care and increase pain research resources. Given the variability among countries in health care policies and programs, resources and educational programs, many of the approaches and strategies outlined will need to be tailored to each country's socioeconomic and educational situation.
journal_name
Pain Res Managjournal_title
Pain research & managementauthors
Sessle Bdoi
10.1155/2011/513423subject
Has Abstractpub_date
2011-11-01 00:00:00pages
416-20issue
6eissn
1203-6765issn
1918-1523journal_volume
16pub_type
杂志文章,评审abstract:BACKGROUND:Reports indicate that characteristics of older adults with chronic pain may be different than those of younger persons. OBJECTIVE:To study the pain characteristics of older patients presenting to a tertiary pain clinic for the first time. METHODS:Age, sex and relative contributions of biomedical versus psy...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2008/541963
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To investigate the emotional and neurobehavioural status of patients suffering from chronic pain. METHODS:Fifteen male patients with chronic lower back pain and 15 healthy control subjects were studied for approximately six months. Pain was measured using a visual analogue scale. The WHO Neurobehavioral Core...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2011/825636
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Exercising for ≥ 150 min/week is a recommended strategy for self-managing arthritis. However, exercise nonadherence is a problem. Arthritis pain anxiety may interfere with regular exercise. According to the fear-avoidance model, individuals may confront their pain anxiety by using adaptive self-regulatory re...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2015/853961
更新日期:2015-03-01 00:00:00
abstract:Background:Occlusal appliances are still widely used instruments in the management of orofacial pain in dentistry, yet alone or as a part of multimodal therapy. However, some of those modalities have been lacking thorough randomized assessment, and there is a conflicting evidence available. It is hypothesized that pain...
journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
doi:10.1155/2019/7954291
更新日期:2019-03-11 00:00:00
abstract:OBJECTIVE:To analyze articles on neonatal pain indexed in MEDLINE from 1965 to 1999. METHODS:Papers published since 1965 and indexed in Medline (PubMed ) were considered. The search strategy was: 'pain' (MeSH terms) OR 'pain' (Title word) OR 'pain' (All Fields), AND 'infant, newborn' (MeSH terms). After the search was...
journal_title:Pain research & management
pub_type: 杂志文章,meta分析
doi:10.1155/2001/213030
更新日期:2001-04-01 00:00:00
abstract:Purpose:We aimed to present our experience in anchoring technique and evaluate the efficacy and safety of unilateral percutaneous vertebroplasty in patients with neurologically intact Kümmell's disease. Methods:From January 2014 to December 2017, 29 patients (17 males and 12 females) with neurologically intact Kümmell...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2020/4145096
更新日期:2020-05-24 00:00:00
abstract:BACKGROUND:Facial responses to pain are believed to be an act of communication and, as such, are likely to be affected by the relationship between sender and receiver. OBJECTIVES:To investigate this effect by examining the impact that variations in communicative relations (from being alone to being with an intimate ot...
journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
doi:10.1155/2014/195286
更新日期:2014-01-01 00:00:00
abstract::Introduction. Pain is unpleasant sensory and emotional experience associated with actual and potential tissue damage. Inadequate pain management has been shown to affect patient outcomes by potentially increasing hospital stay and delaying recovery; thus, the management of pain has major implications for nursing. The ...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2020/6036575
更新日期:2020-03-18 00:00:00
abstract:BACKGROUND:Pregabalin (PGB) is a novel antiepileptic drug and is also used as a first-line medication for the treatment of neuropathic pain. However, the mechanisms of its analgesic effects remain largely unknown. OBJECTIVES:To elucidate the mechanisms underlying the antiallodynic action of PGB in rats with neuropathi...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2014/623830
更新日期:2014-07-01 00:00:00
abstract::The provision of care for patients with type II diabetes in primary care must involve assessing patients for peripheral neuropathy of the feet. Objectives. This paper will demonstrate that painful diabetic neuropathy (PDN) is poorly assessed for and treated in primary care. Methods. A critical analysis of research wil...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2016/1974863
更新日期:2016-01-01 00:00:00
abstract::The purpose of the present article was to assess the available literature concerning pain and autism. First, authors summarized the published articles on pain reactivity in people with autism. Second, the hypotheses envisaged to explain the presence of expressive particularities in people with autism spectrum disorder...
journal_title:Pain research & management
pub_type: 杂志文章,评审
doi:10.1155/2010/749275
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:To provide an overview of the history and pharmacology of cannabis in relation to current scientific knowledge concerning actual and potential therapeutic uses of cannabis preparations and pure cannabinoids. METHODS:The literature on therapeutic uses of cannabis and cannabinoids was assessed with respect to ...
journal_title:Pain research & management
pub_type: 历史文章,杂志文章
doi:10.1155/2001/469629
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:Alexithymia is a disturbance in awareness and cognitive processing of affect that is associated with over-reporting of physical symptoms, including pain. The relationship between alexithymia and other psychological constructs that are often associated with pain has yet to be evaluated. OBJECTIVES:The presen...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2009/468321
更新日期:2009-07-01 00:00:00
abstract:Objectives:Dexmedetomidine is widely used as an adjunct to general anesthesia. In this study, we evaluated the effects of perioperative dexmedetomidine infusion on postoperative analgesia in patients undergoing lateral thoracotomy for thoracic esophageal cancer. Methods:A total of 62 patients undergoing lateral thorac...
journal_title:Pain research & management
pub_type: 杂志文章,随机对照试验
doi:10.1155/2020/4145893
更新日期:2020-05-06 00:00:00
abstract:BACKGROUND:A relationship between smoking and development of pain syndromes has been suggested in the literature. The present study examined associations between smoke exposure and other related variables, and pain response to suprathreshold electrical stimulation. METHODS:Subjects were prospectively recruited from a ...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2008/240573
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:The impact of telephone consultations between pain specialists and primary care physicians regarding the care of patients with chronic pain is unknown. OBJECTIVES:To evaluate the impact of telephone consultations between pain specialists and primary care physicians regarding the care of patients with chroni...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2015/345432
更新日期:2015-11-01 00:00:00
abstract:Objective:To assess the validity of an exposure score obtained from the Xm2 tool for all pharmacological and nonpharmacological strategies used by individuals to manage chronic pain. Methods:Using data from individuals with chronic pain, eXposure multimodal (Xm2) scores were calculated by assigning one point for every...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2018/2530286
更新日期:2018-12-12 00:00:00
abstract:BACKGROUND:Leptin, an adipocyte-produced cytokine, interacts with various hormones, including those of the hypothalamic-pituitary-adrenal axis. Fibromyalgia is a syndrome characterized by widespread pain accompanied by tenderness. The pathogenesis involves a disturbance in pain processing and transmission by the centra...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2012/350654
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Thousands of children undergo surgery each year, and a shift toward same-day surgeries and decreased lengths of hospital stay results in parents being increasingly responsible for their child's postoperative care. Recent studies have tested interventions designed to improve parent management of their childre...
journal_title:Pain research & management
pub_type: 杂志文章,评审
doi:10.1155/2014/938352
更新日期:2014-07-01 00:00:00
abstract::Pain is one of the commonest reasons why children visit the hospital. Inadequately treated pain in children can negatively affect their physical, psychological, and social well-being; it also places financial burden on families of affected children and healthcare systems in general. Considering the eventual suffering ...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2020/7283473
更新日期:2020-02-13 00:00:00
abstract::Background. Oral health-related quality of life (OHRQoL) is impacted by periodontal disease and orofacial pain. There is a limited research examining the impact of avoidance of care or physiological arousal related to the fear of pain response on periodontal-related OHRQoL. Methods. Data are from the Center for Oral H...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2017/5491923
更新日期:2017-01-01 00:00:00
abstract::Histone deacetylase inhibitors (HDACIs), which interfere with the epigenetic process of histone acetylation, have shown analgesic effects in animal models of persistent pain. The HDAC family comprises 18 genes; however, the different effects of distinct classes of HDACIs on pain relief remain unclear. The aim of this ...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2019/1648919
更新日期:2019-01-27 00:00:00
abstract::Chronic pain syndromes are associated with alterations in sleep continuity and sleep architecture. One perspective of this relationship, which has not received much attention to date, is that disturbances of sleep affect pain. To fathom this direction of cause, experimental human and animal studies on the effects of s...
journal_title:Pain research & management
pub_type: 杂志文章,评审
doi:10.1155/2004/949187
更新日期:2004-04-01 00:00:00
abstract:OBJECTIVE:The present randomized, double-blinded, crossover study compared the efficacy and safety of a seven-day buprenorphine transdermal system (BTDS) and placebo in patients with low back pain of moderate or greater severity for at least six weeks. METHODS:Prestudy analgesics were discontinued the evening before r...
journal_title:Pain research & management
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1155/2010/216725
更新日期:2010-05-01 00:00:00
abstract::Chronic back pain is often a result of coexisting pathologies; secondary causes of pain can become more apparent sources of pain once the primary pathology has been addressed. The objective of our study was to determine if there is an increase in diagnosis of Sacroiliac joint pain following a Lumbar Rhizotomy. A list ...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2017/4830142
更新日期:2017-01-01 00:00:00
abstract::There is limited evidence to underpin the assessment and management of pain in children with profound cognitive impairment and these children are vulnerable to poor pain assessment and management. Health professionals working with children with profound cognitive impairment from a single paediatric tertiary referral c...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2016/8617182
更新日期:2016-01-01 00:00:00
abstract::Background. Observers' responses to pain are recently investigated to more comprehensively explain chronic pain (CP) and disability. However, the role of family context, defined as interference in roles, communication, and problem-solving, and how (i.e., through which mechanisms) these variables contribute to CP relat...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2016/6838596
更新日期:2016-01-01 00:00:00
abstract::The purpose of the present review is to correlate recent knowledge of the role of peripheral ionotropic glutamate receptors in the temporomandibular joint and muscle pain from animal and human experimental pain models with findings in patients. Chronic pain is common, and many people suffer from chronic pain condition...
journal_title:Pain research & management
pub_type: 杂志文章,评审
doi:10.1155/2005/860354
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:As the North American population ages, the prevalence of knee osteoarthritis and the surgical interventions (ie, total knee arthroplasty [TKA]) aimed at correcting pain and disability will also rise proportionally. Therefore, efforts to better understand the factors associated with surgical outcomes are warr...
journal_title:Pain research & management
pub_type: 杂志文章
doi:10.1155/2007/394960
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:A pilot study was conducted to assess whether both the rationale and feasibility exist for future randomized clinical trials to evaluate the combined use of naloxone infusion and tramadol/acetaminophen as opioid-sparing drugs in elderly patients undergoing lower extremity joint replacement surgery. DESIGN:Te...
journal_title:Pain research & management
pub_type: 临床试验,杂志文章
doi:10.1155/2009/497217
更新日期:2009-03-01 00:00:00