Abstract:
:We obtained maximum likelihood estimates (MLEs) of the proportion cured pi c and mean log survival time mu t for a sample of 4355 patients with intraocular melanoma whose survival times subsequent to treatment were assumed to follow a log-normal distribution. Following stratification by tumour size, MLEs of pi c and mu t derived for each stratum correlate inversely with tumour size. We then expressed pi c and mu t as continuous functions of tumour size and calculated MLEs for the parameters of these functions from the entire sample. This investigation documents for ocular melanoma a significant relationship of tumour size to both cured fraction and mean log survival time.
journal_name
Stat Medjournal_title
Statistics in medicineauthors
Gamel JW,McLean IW,Rosenberg SHdoi
10.1002/sim.4780090814subject
Has Abstractpub_date
1990-08-01 00:00:00pages
999-1006issue
8eissn
0277-6715issn
1097-0258journal_volume
9pub_type
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