Synthesis and antifungal evaluation of pyrido[1,2-a]indole-1,4-diones and benzo[f]pyrido[1,2-a]indole-6,11-diones.

Abstract:

:Pyrido[1,2-a]indole-1,4-diones and benzo[f]pyrido[1,2-a]indole-6,11-diones were synthesized and tested for in vitro antifungal activity against two pathogenic strains of fungi. Among them tested, many compounds showed good antifungal activity. The results suggest that pyrido[1,2-a]indole-1,4-diones and benzo[f]pyrido[1,2-a]indole-6,11-diones would be potent antifungal agents.

journal_name

Bioorg Med Chem Lett

authors

Ryu CK,Yoon JH,Song AL,Im HA,Kim JY,Kim A

doi

10.1016/j.bmcl.2011.10.092

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

497-9

issue

1

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(11)01499-5

journal_volume

22

pub_type

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