Schizophrenia spectrum disorders, substance misuse, and the four-facet model of psychopathy: the relationship to violence.

abstract：:In 200 inpatients on regular neuroleptics, point prevalence of extrapyramidal syndromes, including Parkinson syndrome, akathisia and tardive dyskinesia (TD), was studied and found to be 20, 11 and 22%, respectively. A total of 46 patients have currently, and for a longer time, (average about 3years, median over 1year)...

journal_title：Schizophrenia research

authors： Modestin J,Stephan PL,Erni T,Umari T

更新日期：2000-05-05 00:00:00

abstract：:Neurological Examination Abnormalities (NEA) are prevalent in schizophrenia, but the significance of this is obscured by methodological problems. The Neurological Evaluation Scale (NES), the most widely used structured neurological examination in schizophrenia research, has had limited study of its inter-rater reliabi...

journal_title：Schizophrenia research

authors： Sanders RD,Forman SD,Pierri JN,Baker RW,Kelley ME,Van Kammen DP,Keshavan MS

更新日期：1998-02-09 00:00:00

abstract：BACKGROUND:Neuroimaging findings implicate bilateral superior temporal regions in the genesis of auditory-verbal hallucinations (AVH). This study aimed to investigate whether 1 Hz repetitive transcranial magnetic stimulation (rTMS) of the bilateral temporo-parietal region would lead to increased effectiveness in the ma...

journal_title：Schizophrenia research

authors： Vercammen A,Knegtering H,Bruggeman R,Westenbroek HM,Jenner JA,Slooff CJ,Wunderink L,Aleman A

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Startle inhibition by weak prepulses (PPI) is studied to understand the biology of information processing in schizophrenia patients and healthy comparison subjects (HCS). The Consortium on the Genetics of Schizophrenia (COGS) identified associations between PPI and single nucleotide polymorphisms in schizoph...

journal_title：Schizophrenia research

authors： Swerdlow NR,Light GA,Sprock J,Calkins ME,Green MF,Greenwood TA,Gur RE,Gur RC,Lazzeroni LC,Nuechterlein KH,Radant AD,Ray A,Seidman LJ,Siever LJ,Silverman JM,Stone WS,Sugar CA,Tsuang DW,Tsuang MT,Turetsky BI,Braff D

更新日期：2014-02-01 00:00:00

abstract：:The guarantee of perceptual coherence for events through everyday life situations depends upon the capacity to correctly integrate series of multi-sensory experiences. Patients with schizophrenia have been shown to reveal a deficit in integrating, i.e., "binding", perceptual information together. However, results in t...

journal_title：Schizophrenia research

authors： Foucher JR,Lacambre M,Pham BT,Giersch A,Elliott MA

更新日期：2007-12-01 00:00:00

abstract：:The role of mentalizing abilities (or theory of mind) and empathic abilities in violent behavior were studied in 24 hospitalized males with paranoid schizophrenia (ICD-10). Patients were divided into violent and nonviolent groups based on their history of committing violent acts against others. To examine these abilit...

journal_title：Schizophrenia research

authors： Abu-Akel A,Abushua'leh K

更新日期：2004-07-01 00:00:00

abstract：:[(3)H]ketanserin binding to 5HT(2A) receptors was measured in the left planum temporale (sensory speech cortex) from schizophrenic and non-schizophrenic (control) subjects using both particulate membranes and tissue sections. There was a significant decrease in the affinity of [(3)H]ketanserin binding to particulate m...

journal_title：Schizophrenia research

authors： Pralong D,Tomaskovic-Crook E,Opeskin K,Copolov D,Dean B

更新日期：2000-07-07 00:00:00

abstract：:We investigated the relationship between the P300, neuropsychological test performance and symptomatology in recent-onset schizophrenic patients (n = 45) to gain insight into underlying mechanisms of abnormal P300 in schizophrenia. The P300 was recorded in two sessions with an intermission of five minutes, at the midl...

journal_title：Schizophrenia research

authors： Nieman DH,Koelman JH,Linszen DH,Bour LJ,Dingemans PM,Ongerboer de Visser BW

更新日期：2002-05-01 00:00:00

abstract：:The degree of cortical atrophy as revealed by computed tomographic scans was assessed in 124 patients meeting the DSM III criteria for schizophrenia and in 45 age- and sex-matched healthy controls. 21 patients, i.e., 33% of the entire sample, showed moderate to severe atrophy. The presence of atrophy was not associate...

journal_title：Schizophrenia research

authors： Vita A,Sacchetti E,Calzeroni A,Cazzullo CL

更新日期：1988-09-01 00:00:00

abstract：:Although factor scores are commonly used to interpret the Weschsler Adult Intelligence Scale--Revised (WAIS-R), the WAIS-R factor structure has not been investigated in patients with schizophrenia. We used confirmatory factor analysis (CFA) to examine five latent construct models in 169 males with schizophrenia. The W...

journal_title：Schizophrenia research

authors： Allen DN,Huegel SG,Seaton BE,Goldstein G,Gurklis JA Jr,van Kammen DP

更新日期：1998-11-09 00:00:00

abstract：BACKGROUND:Family studies have suggested that schizophrenia and bipolar disorders share some susceptibility factors. Schizotypal personality disorder (SPD) may be an intermediate phenotype common both to schizophrenia and bipolar disorders. We explored the familiality of schizotypal dimensions by comparing the magnitud...

journal_title：Schizophrenia research

authors： Schürhoff F,Laguerre A,Szöke A,Méary A,Leboyer M

更新日期：2005-12-15 00:00:00

abstract：:Attention deficits are considered to be fundamental in patients with schizophrenia. During attention tasks, patients with schizophrenia have been shown to display increased brain activity in some neuroimaging studies but reduced brain activity in others. These conflicting findings may be due to some study designs prim...

journal_title：Schizophrenia research

authors： Carter JD,Bizzell J,Kim C,Bellion C,Carpenter KL,Dichter G,Belger A

更新日期：2010-09-01 00:00:00

abstract：:Schizophrenia is a severe psychiatric disorder with lifetime prevalence of ~1% worldwide. A genotyping study was conducted using a custom panel of Illumina 1536 SNPs in 840 schizophrenia cases and 876 controls (351 patients and 385 controls from North India; and 436 patients, 401 controls and 143 familial samples with...

journal_title：Schizophrenia research

authors： Jajodia A,Kaur H,Kumari K,Gupta M,Baghel R,Srivastava A,Sood M,Chadda RK,Jain S,Kukreti R

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Superior temporal gyrus (STG/BA22) volume is reduced in schizophrenia and to a milder degree in schizotypal personality disorder (SPD), representing a less severe disorder in the schizophrenia spectrum. SPD and Borderline personality disorder (BPD) are severe personality disorders characterized by social and...

journal_title：Schizophrenia research

authors： Goldstein KE,Hazlett EA,New AS,Haznedar MM,Newmark RE,Zelmanova Y,Passarelli V,Weinstein SR,Canfield EL,Meyerson DA,Tang CY,Buchsbaum MS,Siever LJ

更新日期：2009-07-01 00:00:00

abstract：:Studying Klinefelter syndrome (47,XXY), a genetically defined disorder characterized by the presence of an additional X chromosome, can reveal insights into genotype-phenotype associations. Increased vulnerability to psychiatric disorders characterized by difficulties in social interactions, such as schizophrenia and ...

journal_title：Schizophrenia research

authors： van Rijn S,Swaab H,Aleman A,Kahn RS

更新日期：2006-06-01 00:00:00

abstract：:Adolescents meeting diagnostic criteria for schizotypal personality disorder (SPD) are presumed to be at risk for developing schizophrenia in adulthood, making them an important group for exploring the developmental trajectory of the disease. Deficits in executive functioning have been documented in schizophrenia pati...

journal_title：Schizophrenia research

authors： Diforio D,Walker EF,Kestler LP

更新日期：2000-04-07 00:00:00

abstract：OBJECTIVE:Despite an increased risk for suicide among individuals diagnosed with psychotic disorders, risk factors for completed suicide remain largely unexamined in this population. Using a case-control design, this study aimed to investigate clinical and behavioural risk factors for suicide completion in schizophreni...

journal_title：Schizophrenia research

authors： McGirr A,Tousignant M,Routhier D,Pouliot L,Chawky N,Margolese HC,Turecki G

更新日期：2006-05-01 00:00:00

abstract：:Recent studies of cerebral pathology in patients with schizophrenia have focused on symptomatological and electrophysiological correlates of reduced temporal lobe structure volumes. Volume deficits of the left superior temporal gyrus have been correlated with auditory hallucinations as well as to left-sided P300 ampli...

journal_title：Schizophrenia research

authors： Havermans R,Honig A,Vuurman EF,Krabbendam L,Wilmink J,Lamers T,Verheecke CJ,Jolles J,Romme MA,van Praag HM

更新日期：1999-08-17 00:00:00

abstract：OBJECTIVE:Acoustic phonetic methods are useful in examining some symptoms of schizophrenia; we used such methods to understand the underpinnings of aprosody. We hypothesized that, compared to controls and patients without clinically rated aprosody, patients with aprosody would exhibit reduced variability in: pitch (F0)...

journal_title：Schizophrenia research

authors： Compton MT,Lunden A,Cleary SD,Pauselli L,Alolayan Y,Halpern B,Broussard B,Crisafio A,Capulong L,Balducci PM,Bernardini F,Covington MA

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Many studies have identified urban-rural differences in the occurrence of schizophrenia. Though unknown, the underlying causes responsible for these differences have been hypothesized to include urban-rural differences in toxic exposures, diet, infections, stress, or an artifact due to selective migration. F...

journal_title：Schizophrenia research

authors： Pedersen CB

更新日期：2015-10-01 00:00:00

abstract：:Twenty-five schizophrenic patients diagnosed by DSM-III-R underwent event-related potentials and magnetic resonance imaging scans. Latency and amplitude of P300 waveform were measured using an auditory odd-ball paradigm. Anterior and posterior volumes of the superior temporal gyrus and medial temporal structure were m...

journal_title：Schizophrenia research

authors： Kawasaki Y,Maeda Y,Higashima M,Nagasawa T,Koshino Y,Suzuki M,Ide Y

更新日期：1997-08-29 00:00:00

abstract：:Previous studies have indicated that schizophrenic patients have olfactory deficits. The question as to whether olfactory deficits are due to chronic effects of medication has not been addressed. This is the first paper to report that never-medicated schizophrenic patients also have olfactory deficits. Twenty four nor...

journal_title：Schizophrenia research

authors： Wu J,Buchsbaum MS,Moy K,Denlea N,Kesslak P,Tseng H,Plosnaj D,Hetu M,Potkin S,Bracha S

更新日期：1993-03-01 00:00:00

abstract：:Patients with schizophrenia exhibit impairments in prepulse inhibition (PPI) of the startle response. Available data suggest that atypical antipsychotics may be more effective than typical antipsychotics in improving PPI deficits in schizophrenia. However, previous studies have used between-subjects rather than longit...

journal_title：Schizophrenia research

authors： Martinez-Gras I,Rubio G,del Manzano BA,Rodriguez-Jimenez R,Garcia-Sanchez F,Bagney A,Leza JC,Borrell J

更新日期：2009-12-01 00:00:00

abstract：:Schizophrenia is modelled as a neurodevelopmental disease with high heritability. However, established markers like cortical thickness and grey matter volume are heavily influenced by post-onset changes and thus provide limited possibility of accessing early pathologies. Gyrification on the other side is assumed to be...

journal_title：Schizophrenia research

authors： Spalthoff R,Gaser C,Nenadić I

更新日期：2018-12-01 00:00:00

abstract：:The memory profile of acute and chronic schizophrenic patients was examined according to the information processing model, with which encoding, retention and retrieval processes of these patients were compared. The effects of an external organizational strategy on their verbal learning and memory were also examined. T...

journal_title：Schizophrenia research

authors： Chan AS,Kwok IC,Chiu H,Lam L,Pang A,Chow LY

更新日期：2000-02-14 00:00:00

abstract：BACKGROUND:Previous studies have shown that individuals with schizophrenia exhibit higher levels of unhelpful metacognitive beliefs than healthy controls, but no studies have explored metacognitive beliefs in early psychosis. AIMS:We examined i) differences in levels of unhelpful metacognitive beliefs between psychosi...

journal_title：Schizophrenia research

authors： Østefjells T,Melle I,Hagen R,Romm KL,Sönmez N,Andreassen OA,Røssberg JI

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Verbal and visual memory deficits are prominent trait markers for schizophrenia, with impairments also observed in first-degree relatives [Snitz, B.E., Macdonald, A.W., 3rd, & Carter, C.S. (2006). Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: a meta-analytic review of put...

journal_title：Schizophrenia research

authors： Skelley SL,Goldberg TE,Egan MF,Weinberger DR,Gold JM

更新日期：2008-10-01 00:00:00

abstract：:Little is known about the impact of family history of psychosis on youth from community samples. To fill this gap, we compared youth with a first-degree relative with psychosis spectrum symptoms (i.e. family history of psychosis spectrum symptoms, FHPS) to youth without FHPS in a cross-sectional analysis of the Philad...

journal_title：Schizophrenia research

authors： Taylor JH,Asabere N,Calkins ME,Moore TM,Tang SX,Xavier RM,Merikangas AK,Wolf DH,Almasy L,Gur RC,Gur RE

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Cognitive deficits are prominent in schizophrenia and represent promising endophenotypes for genetic research. METHODS:The current study investigated the importance of two conceptually distinct genetic aggregates, one based on copy number variations (uncommon deletion burden), and one based on single nucleo...

journal_title：Schizophrenia research

authors： Yeo RA,Gangestad SW,Walton E,Ehrlich S,Pommy J,Turner JA,Liu J,Mayer AR,Schulz SC,Ho BC,Bustillo JR,Wassink TH,Sponheim SR,Morrow EM,Calhoun VD

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:International studies indicate that the median prevalence of psychotic experiences in children is 7%. It has been proposed that environmental stress during pregnancy may affect the neurodevelopment of the foetus and lead to a vulnerability in the child to later stressors and psychopathology. AIM:In this stu...

journal_title：Schizophrenia research

authors： Dorrington S,Zammit S,Asher L,Evans J,Heron J,Lewis G

更新日期：2014-01-01 00:00:00