Abstract：
:Despite the significant reduction in mortality, ischemic stroke is the leading cause of morbidity and mortality in adults in industrialized countries. Antiplatelet therapy has reduced the risk of stroke and other vascular events. Although most commonly used treatment is aspirin, other antiplatelet drugs with different mechanisms of action have been developed. Clopidogrel blocks platelet aggregation by inhibiting the adenosine diphosphate receptor and the subsequent activation of the complex IIb/IIIa. In addition to its antiplatelet action, it also has pleiotropic effects, reducing the inflammatory mechanisms that occur during ischemia. Clopidogrel has demonstrated a benefit over aspirin in preventing vascular events, especially in patients at high cardiovascular risk. In this paper we review the main studies that have been conducted with clopidogrel in preventing ischemic stroke, either as monotherapy or in combination with other antiplatelet agents.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Rodríguez-Yáñez M,Arias-Rivas S,Fernández-Ferro J,Leira R,Castillo J,Blanco Msubject
Has Abstractpub_date
2011-11-01 00:00:00pages
561-73issue
9eissn
0210-0010issn
1576-6578pii
rn2011371journal_volume
53pub_type
杂志文章,评审abstract：INTRODUCTION:Lesions of the pyramidal system are characterized by their effects on qualitative aspects of movement. One of the features of pyramidal defects is the presence of associated movements or synkinesis. CLINICAL CASE:We present a case with residual associated electromyographic (EMG) response in a patient who ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-06-01 00:00:00
abstract：:We present a family study of multiple cavernomatosis which affected a boy of six, his mother and two brothers. It was seen clinically as epileptic crises, focal neurological defects and frequent headaches. In our case, the condition started as a syndrome of intracranial hypertension with progressive headache and vomit...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：:The presence of oligoclonal bands (OCB) of immunoglobulin G (IgG) is in our days the most useful finding in the study of the CSF for the diagnosis of multiple sclerosis (MS). The most sensitive method for the detection of OCB is the isoelectric focusing followed by immunoblotting. The prevalence of OCB changes in diff...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-06-16 00:00:00
abstract：INTRODUCTION:Currently, clinical benefits of stroke units and thrombolysis in ischaemic stroke are evidence-based. However, inequities in coverage and in treatment provided to these patients still persist due to geographical differences in residence, technological capacity and organization among health care systems. Te...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2012-01-01 00:00:00
abstract：:Based on the interrelation between science and philosophy, this article addresses the impact of neurosciences on the philosophical issues posed by today's society, especially those related with epistemology and the philosophy of science. To do so, the different approaches in the cognitive sciences are taken into accou...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2013-03-16 00:00:00
abstract：AIM:To describe clinical results and complications derived from vagal nerve stimulation therapy in drug resistant epileptic patients unsuitable for other surgical treatments, since the first implant in an epilepsy national referral centre. PATIENTS AND METHODS:A retrospective analysis of the patients implanted in our ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVE:To present the first Spanish case, perhaps the first non-Canadian, with ataxia type Charlevoix-Saguenay. CLINICAL CASE:A patient with important psychomotor delay and non-progressive ataxia has been studied in our Service during the first years of life and his follow-up has been carried out until 30 years of ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-07-01 00:00:00
abstract：INTRODUCTION AND DEVELOPMENT:Frontal lobe, more specifically prefrontal cortex, is one of the brain regions that undergoes more protracted ongoing development. The wider the developmental window of one brain structure, the more vulnerable the functions related to it. Hence, executive functions, which are mediated by pr...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-07-16 00:00:00
abstract：AIMS:The purpose of this study is to collect and evaluate the experimental evidence suggesting that acetaldehyde, the first oxidative metabolite of ethyl alcohol (ethanol), plays a mediating role in the brain damage associated with the chronic consumption of this substance. DEVELOPMENT:Although the brain damage associ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2003-09-01 00:00:00
abstract：INTRODUCTION:The SOX5 gene encodes a transcription factor involved in the regulation of chondrogenesis and the development of the nervous system. CASE REPORT:We report a 10 years-old girl with developmental delay, behavior problems and dysmorphic features of this new syndrome with developmental delay. She had a 12p12 ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2015-05-16 00:00:00
abstract：:Traffic accidents (TA) are, after heart disease, cancer and stroke, the fourth death cause among the general population. Although the number of AT caused by diseases-excluding alcoholism- seems to be reduced, interaction between organic pathology and functional ability increases the importance of this problem. This pa...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1995-03-01 00:00:00
abstract：INTRODUCTION:Infantile autism is a disorder that is characterised by alterations affecting reciprocal social interactions, abnormal verbal and non-verbal communication, poor imaginative activity and a restricted repertoire of activities and interests. The causes of autism remain unknown, but there are a number of diffe...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2009-02-27 00:00:00
abstract：TITLE:Polimiositis secundaria a un linfoma no Hodgkin. : ...
journal_title：Revista de neurologia
pub_type： 信件
doi：
更新日期：2017-04-01 00:00:00
abstract：INTRODUCTION:For conscious behaviours to continue, attention and working memory must be brought into play in order to match the data from the current reality with those in the long-term memory and to the sequential plans for adaptive action. PATIENTS AND METHODS:We present the preliminary findings of our study of 50 p...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2005-01-15 00:00:00
abstract：INTRODUCTION:Significant progress in the understanding of the molecular genetics and pathophysiology of inherited neuropathies has been achieved during the last years. DEVELOPMENT:The causative genetic defects of most of the demyelinating forms are known and different chromosomal loci have been identified for the rare...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2001-01-16 00:00:00
abstract：INTRODUCTION:Fingolimod is a selective immunosuppressant that targets the S1P receptor, and is indicated in the treatment of aggressive relapsing-remitting multiple sclerosis (RRMS) and following treatment failure with first-order drugs. AIM:To investigate the safety and effectiveness of fingolimod under the condition...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2017-05-16 00:00:00
abstract：INTRODUCTION:The hyperperfusion syndrome (HS) is described as an infrequent complication of carotid endarterectomy. It may also occur in percutaneous transluminal carotid angioplasty with a similar causal mechanism and clinical features to those seen in HS related to carotid endarterectomy. CLINICAL CASE:We describe t...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-11-16 00:00:00
abstract：:The most relevant data presented at the 29th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), held in October 2013 in Denmark, were summarised at the sixth edition of the Post-ECTRIMS Expert Meeting, held in Madrid in October 2013, resulting in this review, to be published...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2014-09-16 00:00:00
abstract：AIM:To document reversible cognitive deterioration associated to high doses of zonisamide, using the Reliable Change Index to control practice effects derived from repetitive neuropsychological assessments. CASE REPORT:A 11 year-old boy with tuberous sclerosis complex and left frontal refractory epilepsy, evaluated wi...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2015-01-16 00:00:00
abstract：INTRODUCTION:The thoracic outlet syndromes are clinical conditions whose true incidence is low, although they are frequently diagnosed. They are caused by compression of the brachial plexus or vascular structures due to anatomical anomalies of the cervico-axillary region. DEVELOPMENT:Two main types are seen: the neuro...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1998-07-01 00:00:00
abstract：:It has been stated that findings in neonatal neurological examinations can play a role as a pointer to adverse developmental outcome. The description of the examinations, and their presence or absence differed among authors without clear reference to their physiological variability ranges. We approached the study of s...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
abstract：INTRODUCTION:An important aim of neuropsychological assessment is to identify impairment in higher cognitive or intellectual, functioning. In order to achieve this task the assessment of premorbid intellectual ability becomes crucial. The estimation of premorbid cognitive functioning will allow us to assess level of co...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-03-01 00:00:00
abstract：INTRODUCTION:In the last years, the changes in glial cells during different alterations in the Central Nervous System have been studied. It is known that astrocytes and microglial cells are the glial cells which present the major reactivity. OBJECTIVE:The aim of this work was to analyze the glial cell changes induced ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-09-01 00:00:00
abstract：INTRODUCTION:Opsoclonus myoclonus is a rare neurological syndrome affecting children and adults, and which is characterised by a sudden onset of chaotic eye movements and myoclonias. In children it generally appears before the age of three as a parainfectious or paraneoplasic process; the type of tumour most frequently...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-08-16 00:00:00
abstract：INTRODUCTION:Malaria is one of the main health problems in the Third World. Plasmodium falciparum infects as many as 300 million people, causing up to three million deaths each year, most of which occur in African children. Cerebral malaria is the most common lethal complication of P. falciparum infection in children a...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：TITLE:Signo de la banda en la esclerosis lateral primaria. : ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：10.33588/rn.6901.2019079
更新日期：2019-07-01 00:00:00
abstract：INTRODUCTION:Essential thrombocythemia (ET) is a myelodysplastic syndrome that constitutes an infrequent cause of ischemic stroke. Few clinical reports have been published describing the clinical onset of ET in the form of a vascular accident. CASE REPORT:We describe four cases of patients with no known haematological...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-06-01 00:00:00
abstract：INTRODUCTION:Numerous drugs have been related to exacerbation of myasthenia gravis. So far there are no studies examining the extent of use of drugs related to exacerbation of myasthenia gravis. AIMS:We sought to assess the extent of use of drugs related to exacerbations and the annual incidence rate of exacerbations ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：10.33588/rn.7104.2020198
更新日期：2020-08-16 00:00:00
abstract：AIM:To assess the budget impact of the treatment for relapsing remitting multiple sclerosis (RRMS), interferons, and glatiramer acetate, from the National Health System perspective in Spain. PATIENTS AND METHODS:A budget impact model was designed to compare the cost of RRMS treatment in different settings, using a fiv...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2011-08-01 00:00:00
abstract：INTRODUCTION:Severe myoclonic epilepsy in infancy (SMEI), or Dravet s syndrome, is one of the most serious forms of epilepsy in infancy. In this study we analyse the clinical characteristics of the process. PATIENTS AND METHODS:The cases reported in the literature are surveyed, together with a personal casuistic, from...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
