Abstract：
:The ability of Phlebotomus langeroni to successfully acquire and transmit Leishmania infantum MON-98 to hamsters was demonstrated. Sand flies and Leishmania both originated from an infantile visceral leishmaniasis focus in El Agamy Egypt. P. langeroni females were infected by feeding on lesions of needle-inoculated hamster and on infected blood suspension using a chick-skin membrane apparatus. Infection rate of sand flies fed on membrane was 88% compared to 7.8% for flies fed on leishmanial lesion. The transmission to hamster took place by the bites of infective flies taking a second blood meal, on the 8th to 10th day post-feeding. Furthermore, successful transmission was by the bites of flies that took no blood or that took full blood meal. Whereas flies that took full blood meal were not infective as indicated by dissection. In three hamsters, lesions developed after three months. Leishmania amastigotes were demonstrated from the lesion as well as from the liver and spleen of infected hamsters.
journal_name
Acta Tropjournal_title
Acta tropicaauthors
El Sawaf BM,Doha SA,Imam MIdoi
10.1016/j.actatropica.2011.08.008subject
Has Abstractpub_date
2012-01-01 00:00:00pages
44-6issue
1eissn
0001-706Xissn
1873-6254pii
S0001-706X(11)00250-6journal_volume
121pub_type
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