Abstract:
:Highly active antiretroviral therapy (HAART) treatment for HIV has changed the course of AIDS in societies in which the drugs are readily available. Despite the great success of HAART, drug resistance and toxicity issues still remain a concern for some individuals. Thus, a number of investigators have been exploring other approaches for inhibiting HIV-1 replication. One of the most potent of these is the use of RNA interference (RNAi). This review will focus solely on the use of RNAi for the treatment of HIV-1 infection, including the problems, progress and future prospects.
journal_name
Gene Therjournal_title
Gene therapyauthors
Zhou J,Rossi JJdoi
10.1038/gt.2011.149subject
Has Abstractpub_date
2011-12-01 00:00:00pages
1134-8issue
12eissn
0969-7128issn
1476-5462pii
gt2011149journal_volume
18pub_type
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