Abstract:
INTRODUCTION AND HYPOTHESIS:Intravesical instillations of hyaluronic acid (HA) and chondroitin sulfate (CS) may lead to regeneration of the damaged glycosaminoglycan layer in interstitial cystitis/bladder pain syndrome (IC/BPS). METHODS:Twenty-two patients with IC/BPS received intravesical instillations (40 ml) of sodium HA 1.6% and CS 2.0% in 0.9% saline solution (IALURIL, IBSA) once weekly for 8 weeks, then once every 2 weeks for the next 6 months. RESULTS:The score for urgency was reduced from 6.5 to 3.6 (p = 0.0001), with a reduction in pain scores from an average of 5.6 to 3.2 (p = 0.0001). The average urine volume increased from 129.7 to 162 ml (p < 0.0001), with a reduction in the number of voids in 24 h, from 14 to 11.6 (p < 0.0001). The IC Symptom and Problem Index decreased from 25.7 to 20.3 (p < 0.0001), and the Pain Urgency Frequency score, from 18.7 to 12.8 (p < 0.0001). CONCLUSION:The treatment appeared to be effective and well tolerated in IC/BPS in this initial experience.
journal_name
Int Urogynecol Jjournal_title
International urogynecology journalauthors
Porru D,Leva F,Parmigiani A,Barletta D,Choussos D,Gardella B,Daccò MD,Nappi RE,Allegri M,Tinelli C,Bianchi CM,Spinillo A,Rovereto Bdoi
10.1007/s00192-011-1546-5subject
Has Abstractpub_date
2012-09-01 00:00:00pages
1193-9issue
9eissn
0937-3462issn
1433-3023journal_volume
23pub_type
临床试验,杂志文章abstract:INTRODUCTION AND HYPOTHESIS:The aim of this study was to investigate patient-reported goals after a tension-free vaginal tape operation for stress urinary incontinence and the correlation with postoperative incontinence. METHODS:A prospective study involving 70 women was carried out. Preoperatively, patients completed...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3049-x
更新日期:2016-12-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Management of stress urinary incontinence (SUI) with intravaginal devices is an alternative to surgical management, but data of a high level of evidence remain scarce. Our goal was to assess efficacy, tolerance, and acceptability of the 75NC007 intravaginal device for SUI management. METHOD...
journal_title:International urogynecology journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00192-012-1814-z
更新日期:2012-12-01 00:00:00
abstract:INTRODUCTION:Vacuum-assisted vaginal delivery (VAVD) is considered a major risk factor for obstetric anal sphincter injuries (OASIS). However, it is difficult to estimate its true contribution to the occurrence of OASIS, as its performance may be confounded by other determinants. Therefore, we aimed to evaluate the ass...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04534-8
更新日期:2020-09-30 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:To examine changes in sexual function after abdominal and transvaginal pelvic organ prolapse repair. METHODS:Women enrolled in our prospective, longitudinal prolapse database with abdominal sacrocolpopexy (ASC) or transvaginal (TVR) pelvic organ prolapse (POP) repair with or without mesh, b...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3066-9
更新日期:2016-12-01 00:00:00
abstract::Genitourinary syndrome of menopause (GSM) is common among postmenopausal women, but, in general, not all of the patients seek medical advice as this sensitive issue can cause them embarrassment. OBJECTIVES:To explore the prevalence of GSM among Thai postmenopausal women and their disclosure of and attitude towards GS...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-03991-0
更新日期:2019-11-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The impact of surgery on pelvic floor muscle (PFM) function remains uncertain. There is a pressure differential along the length of the vagina, influenced by surrounding active and passive tissue structures, giving rise to a pressure profile. The aim of this study is to determine if an intra...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04576-y
更新日期:2020-11-16 00:00:00
abstract:INTRODUCTION AND HYPOTHESES:There is no consensus regarding pregnancy after mid-urethral sling (MUS) operation, and some clinicians recommend postponing the MUS operation if a woman considers further pregnancies or routinely suggest cesarean section as the delivery method after MUS operations. Our primary aim was to as...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04497-w
更新日期:2021-01-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:A great variety of conservative and surgical procedures to correct vaginal vault prolapse have been reported. The aim of this study was to describe practice pattern variation-the difference in care that cannot be explained by the underlying medical condition-among Dutch gynecologists regardi...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-3832-y
更新日期:2019-04-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of this study was to look for possible predictors preoperatively for the development of de novo stress urinary incontinence (SUI) in urodynamically continent women who underwent pelvic reconstructive surgery (PRS). MATERIALS AND METHODS:Medical records of 637 continent women who und...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-015-2685-x
更新日期:2015-09-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The objective was to assess the efficacy of intravesical hyaluronic acid (HA) and chondroitin sulfate (CS), alone or in combination, for recurrent urinary tract infections (RUTIs) in adult female patients using a systematic review and meta-analysis. METHODS:English-language articles were ob...
journal_title:International urogynecology journal
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00192-017-3508-z
更新日期:2018-07-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The Patient Global Impression of Improvement (PGI-I) and International Consultation of Incontinence Questionnaire - Short Form (ICIQ-SF) are validated instruments for the assessment of patient reported outcome measures (PROM) following treatment of stress urinary incontinence (SUI). However,...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3070-0
更新日期:2017-01-01 00:00:00
abstract:AIM:Urogynaecological conditions can have a significant impact on body image. Patient-reported outcome measures (PROMs) are widely used in urogynaecology to assess symptoms and their impact on quality of life. This systematic review aimed to identify currently available PROMs used to assess body image within a urogynae...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-019-03924-x
更新日期:2019-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of the study was to determine whether a 6-week course of 5 mg of solifenacin succinate used to treat mixed incontinence, produces measurable changes in the appearance of the urethral sphincter. METHODS:Twenty-six women undergoing treatment for mixed incontinence were recruited from ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-011-1410-7
更新日期:2011-08-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The literature presents controversial results regarding the role of delivery mode in pelvic floor muscle (PFM) function after birth. Some studies showed a greater impairment of PFM function after vaginal delivery compared with cesarean section, while others have not identified a significant ...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-020-04231-6
更新日期:2020-08-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:We hypothesized that patient-reported urinary symptoms and urodynamic evaluation improve after laparoscopic sacrocolpopexy (LSC) despite deeper vesicovaginal space dissection. METHODS:This was a retrospective study of women with pelvic organ prolapse who underwent LSC from January 2013 to J...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3306-7
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVES:The systematic review and meta-analysis were performed to summarize the available evidence and assess the efficacy of telemedicine for urinary incontinence in women. METHODS:PUBMED, EMBASE, Web of Science, The Cochrane Library, CBM, CNKI, WanFang, and VIP databases were electronically searched to identify e...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-020-04340-2
更新日期:2020-08-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:We sought to determine whether baseline characteristics predict which overactive bladder (OAB) patients benefit from fesoterodine 8 mg versus 4 mg. METHODS:In double-blind, placebo-controlled, flexible-dose trials, baseline characteristics of OAB patients with ≥ 1 urgency urinary incontinen...
journal_title:International urogynecology journal
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00192-018-3640-4
更新日期:2019-02-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The objective was to compare clinical and anatomical outcomes between laparoscopic uterosacral ligament suspension (LUSLS) and vaginal colposuspension using the Uphold Lite™ mesh system for the treatment of apical prolapse. METHODS:We performed a comparative, retrospective cohort study. All...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04563-3
更新日期:2020-10-21 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Jorge and Wexner devised a questionnaire for anal incontinence (AI), known as the Wexner scale (WS). Specific validated questionnaires are essential for the assessment of symptom severity. The objective was to accomplish the cultural adaptation and validation of the Portuguese version of the...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-015-2927-y
更新日期:2016-06-01 00:00:00
abstract:INTRODUCTION:Recurrent urethral diverticulum has been reported in 23% of cases after primary repair and can be difficult to manage. The aim of this video is to demonstrate a surgical technique of repairing a recurrent diverticulum in a woman who had two previous procedures, one with a Martius labial fat pad graft. MET...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04357-7
更新日期:2020-12-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Open transabdominal repair of vesicovaginal fistula (VVF) requires a long cystotomy incision, suprapubic drainage and delayed recovery. Laparoscopic repair is limited by difficult suturing in pelvic procedures. Therefore, the utility of robotic assistance is being increasingly explored. We s...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3194-2
更新日期:2017-06-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:No previous studies have investigated the efficacy of mirabegron 50 mg as the first-line therapy in OAB patients. Hence, the primary objective of this study was to evaluate the efficacy of mirabegron in treatment-naive patients in comparison with those who had discontinued antimuscarinic the...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-016-3219-x
更新日期:2017-07-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Ongoing debate exists about whether the rectovaginal septum (Denonvilliers' fascia) is myth or reality. This study evaluates magnetic resonance images (MRI) of women with Müllerian agenesis for the presence of fascial layers between the rectum and the bladder to test the hypothesis that this...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-013-2214-8
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Currently, there is no global outcome assessment index in prolapse research. Patient Global Impression of Improvement (PGI-I) has only been validated in incontinence. Our aim was to validate its use following prolapse surgery. METHODS:Women with prolapse were recruited from waiting lists an...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-009-1069-5
更新日期:2010-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:The aim of this study was to compare the results of repair of isolated, recurrent, posterior vaginal wall prolapse using standard posterior colporrhaphy versus non-absorbable polypropylene mesh in a routine health care setting. METHODS:This cohort study was based on prospectively collected ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-018-03856-y
更新日期:2019-10-01 00:00:00
abstract::Laparoscopic ventral mesh rectopexy (VMR) has become a popular surgical technique for treating women with full-thickness rectal prolapse with a low recurrence rate, as demonstrated by several studies. In addition, it is increasingly applied to female patients with obstructive defecation syndrome (ODS) caused by intuss...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-017-3378-4
更新日期:2017-07-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:To evaluate the effects of sacral neuromodulation (SNM) on pregnancy and the impact of delivery on SNM function. METHODS:A systematic search was conducted through January 2016. We selected studies including women who had SNM and a subsequent pregnancy. RESULTS:Out of 2,316, eight studies w...
journal_title:International urogynecology journal
pub_type: 杂志文章,评审
doi:10.1007/s00192-017-3272-0
更新日期:2017-09-01 00:00:00
abstract::Aggressive angiomyxoma is a rare soft tissue tumor of the pelvis. Notorious for its locally infiltrative behavior, this tumor is identified by pathological appearance. Grossly gelatinous, spindle cells widely separated by collagen fibrils with vascular components can be microscopically visualized. Wide local excision ...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-012-1867-z
更新日期:2013-05-01 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:Urinary tract infections (UTIs) are common with indwelling catheter use. Our primary aim was to compare UTI rates in women sent home after surgery with continuous bladder drainage versus a urinary catheter valve. METHODS:This was a non-inferiority prospective randomized controlled study bet...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04436-9
更新日期:2020-07-18 00:00:00
abstract:INTRODUCTION AND HYPOTHESIS:A variety of pharmacological and non-pharmacological interventions have been investigated, with the goal of relieving pain after post-episiotomy repair. We aimed to compare the efficacy of tramadol versus celecoxib orally in reducing pain after mediolateral episiotomy repair in obese primigr...
journal_title:International urogynecology journal
pub_type: 杂志文章
doi:10.1007/s00192-020-04411-4
更新日期:2020-07-20 00:00:00