Abstract：
INTRODUCTION:The prevalence of obesity, a serious public health problem, is increasing among teenagers and thus also increases cardiovascular morbidity and mortality in adulthood. OBJECTIVE:To provide a systematic review of the best evidence about the effect of sibutramine and orlistat in weight loss, quality of life and its adverse effects in adolescents diagnosed with obesity. METHODS:We searched electronic databases and bibliographies of selected articles were inspected for any further reference. We included only randomized controlled trials that met a set of predefined criteria. The studies were reviewed by a narrative synthesis. RESULTS:We included 6 randomized controlled trials of sibutramine and 3 of orlistat. The majority reached a moderate to high methodological quality. Sibutramine and orlistat showed a reduction in body mass index (BMI) that was significantly higher compared with the placebo group. We also found a variation of weight with these drugs significantly better than placebo. Only one trial evaluated the quality of life. The incidence of adverse effects was similar for sibutramine and placebo, except for tachycardia. The most common adverse reactions associated with orlistat were gastrointestinal, mild to moderate. CONCLUSIONS:Sibutramine and orlistat in combination with a hypocaloric diet and changes in lifestyle in obese adolescents achieve a short-term loss of weight greater than that achieved through the dietary-behavioral therapy alone.
journal_name
Nutr Hospjournal_title
Nutricion hospitalariaauthors
García Díaz E,Martín Folgueras Tdoi
10.1590/S0212-16112011000300004subject
Has Abstractpub_date
2011-05-01 00:00:00pages
451-7issue
3eissn
0212-1611issn
1699-5198pii
S0212-16112011000300004journal_volume
26pub_type
杂志文章,meta分析,评审abstract：OBJECTIVE:The objective of this study was to determine associations between abdominal obesity (AOb) and the other components of metabolic syndrome (MetS) in young Mexicans in a cross-sectional survey completed during a 4 year period. METHODS:This cross-sectional study reports on components and prevalence of MetS by us...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.20960/nh.171
更新日期：2017-03-30 00:00:00
abstract：INTRODUCTION:Cancer of the oral cavity ranks twelfth worldwide. This type of cancer is usually managed surgically followed by radiotherapy, which may be indicated alone or with chemotherapy; this type of therapies have significant functional side effects on the nutritional status of the patient. OBJECTIVE:The aim of t...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.3305/nh.2013.28.5.6591
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the prevalence of anaemia and the risk of haemoconcentration and its risk factors during all 3 trimesters of pregnancy in women in a Mediterranean area in the south of Europe. MATERIAL AND METHODS:Longitudinal study of 11,259 women whose pregnancies were monitored at primary care centres between ...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.20960/nh.1045
更新日期：2018-01-10 00:00:00
abstract：INTRODUCTION:The rapid increase on life-expectancy represents a major challenge and economic burden for modern societies. Several studies have focused on the effects of polyunsaturated fatty acids (PUFA) upon the immune system; however less attention has been paid to the effects of monounsaturated fatty acids (MUFA). I...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.3305/nh.2013.28.2.6183
更新日期：2013-03-01 00:00:00
abstract：:Flavonoids are a group of natural substances that are located in sources of vegetal origin. More than 4,000 varieties of flavonoids have been identified. All of them are phenyl-benzopyrones of low molecular weight with a basic structure formed by two benzene rings united through a heterocyclic pyrane or pyrone. Beside...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章,评审
doi：
更新日期：2007-05-01 00:00:00
abstract：INTRODUCTION:southern European, Middle Eastern, and North African countries bordering the Mediterranean share dietary habits characterized by moderation and a variety of foods, notably fruit and vegetables. These customs are becoming modified due to social and economic changes. An adequate intake of water and other dri...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.3305/nh.2015.32.6.9892
更新日期：2015-12-01 00:00:00
abstract：:Home enteral nutrition (HEN) is a type of enteral nutrition (EN) which is becoming progressively more widespread in pediatrics due to the benefits it affords to patients, their families and to reducing hospital costs. However, the true extent of its use is unknown in Spain as the data-base set up for this purpose is s...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：
更新日期：2010-09-01 00:00:00
abstract：:The reliability of the information collected in dietary assessment can be affected by different factors. One of the main sources of error in dietary assessment is misreporting which encompass under- and overreporting. Underreporting of food intake is one of the major problems in the assessment of habitual dietary inta...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章,评审
doi：10.3305/nh.2015.31.sup3.8760
更新日期：2015-02-26 00:00:00
abstract：OBJECTIVE:To evaluate body composition differences between children that were born small (SGA) or large for gestational age (LGA) compared with their counterparts born adequate for gestational age (AGA). METHODS:Body composition was assessed in 124 healthy Caucasian children (50% girls) aged 6-10, classified according...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.1590/S0212-16112011000500008
更新日期：2011-09-01 00:00:00
abstract：Introduction:Objective: iron deficiency anemia is associated with adverse results for health and it is highly prevalent worldwide. The current study evaluated the prevalence and the sociodemographic factors associated with iron deficiency anemia in a sample of Colombian pregnant women. Materials and methods: the second...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.20960/nh.1895
更新日期：2019-03-07 00:00:00
abstract：Introduction:Objective: to identify cytokines and to associate them with several indexes of total and central adiposity in young female undergraduate students. Methods: 58 young female sophomore students, aged 18 to 25 years, from a Brazilian public university were evaluated. Both anthropometric measures (weight, heigh...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.20960/nh.02860
更新日期：2020-04-16 00:00:00
abstract：OBJECTIVE:Recently, it has been reported that food choices of relatives of eating disorder (ED) patients are not adequate having in mind a healthy model of eating habits. The aim of this study was to analyse how work conditions relate to parents' food choice coping strategies in both families with a member suffering fr...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.3305/nutr hosp.v28in06.6840
更新日期：2013-11-01 00:00:00
abstract：:Calcium (Ca) is the most abundant mineral element in our body. It accounts for about 2% of body weight. The functions of calcium are: a) functions skeletal and b) regulatory functions. Bone consists of a protein matrix that mineralizes mainly with calcium (the most abundant), phosphate and magnesium, for it is essent...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章,评审
doi：10.20960/nh.341
更新日期：2016-07-12 00:00:00
abstract：:We present a case of a 46-year-old woman who is hospitalized in March of 1997 for a picture of severe mixed malnutrition. We describe the clinical history since the diagnosis of an endometrium carcinoma in 1995, treated with radiation therapy, with the aim of determining the etiology of the severe malnutrition picture...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVE:To evaluate oro-cecal intestinal transit time (ITT) before and after administration of a dairy product containing Bifidobacterium BB12, Lactobacillus casei CRL 431 and fiber in healthy women. METHODS:A prospective, randomised, double-blind and cross-over study with a 4-phase design (run-in: time 0 [T0], two ...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章,随机对照试验
doi：10.3305/nh.2012.27.4.5770
更新日期：2012-07-01 00:00:00
abstract：UNLABELLED:Recent studies have reflected the prevalence of malnutrition within the hospital sphere. The high incidence of malnutrition in hospitals and the negative effect this has on the evolution of patients, since complications are significantly greater in undernourished patients, make it important to find out the n...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：Introduction:Our world is facing an unprecedented challenge. By 2050, the global population is predicted to increase to nine billion people, whom we must nourish on a planet with limited resources. A transformation of the global food system is needed, from an unsustainable to a sustainable food production, and from low...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.20960/nh.03356
更新日期：2021-01-13 00:00:00
abstract：:A big proportion of patients with biliary and pancreatic surgery present preoperative malnourishment aggravated by perioperative fasting and additional therapies. Surgery of the pancreas and the biliary tract may cause digestive impairments, mainly absorptive, especially with fat malabsorption. Many studies have shown...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章,评审
doi：
更新日期：2008-05-01 00:00:00
abstract：INTRODUCTION:Cervical cancer and cervical intraepithelial neoplasia (CIN) require a careful selection of conventional and complementary therapies. The inclusion of dietary supplements within the aforementioned treatments set the tone within treatments. However, there are no reports of what kind of supplements could be ...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章,评审
doi：10.3305/nutr hosp.v28in06.6816
更新日期：2013-11-01 00:00:00
abstract：Introduction:Introduction: in Mexico the main problem in public health is obesity and other diseases that are associated whit this condition, including oral health. Objective: to evaluate the effect of metformin treatment in patients with class I obese on the activity of metalloproteinases present in periodontium with ...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.20960/nh.02602
更新日期：2019-10-17 00:00:00
abstract：OBJECTIVES:The objectives of this study were to assess the quality of life (QoL), nutritional status, and quantitative food intakes of non-terminal admitted cancer patients receiving oral feeding. As well as to evaluate what kind of relation exists between the quality of life, and the nutritional status and current int...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
abstract：Introduction:The current COVID-19 pandemic mainly affects older people, those with obesity or other coexisting chronic diseases such as type-2 diabetes and high blood pressure. It has been observed that about 20 % of patients will require hospitalization, and some of them will need the support of invasive mechanical ve...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.20960/nh.03180
更新日期：2020-07-13 00:00:00
abstract：:Introducción: los problemas relacionados con el peso constituyen un problema importante de salud pública debido a su alta prevalencia y a las adversas consecuencias que tienen para la salud.Objetivo: el objetivo principal de este estudio fue analizar si la depresión y la ansiedad tienen un papel mediador en la relació...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.20960/nh.395
更新日期：2016-07-19 00:00:00
abstract：INTRODUCION:sarcopenia is defined as a syndrome characterized by progressive and generalized loss of muscle mass and strength. The main cause of sarcopenia is the alteration of protein metabolism, in which the proteolytic processes are not accompanied by an appropriate protein synthesis and muscle cells lose progressiv...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章,评审
doi：10.3305/nh.2015.32.5.9638
更新日期：2015-11-01 00:00:00
abstract：:Current medical treatment of type 2 diabetes mellitus (T2DM) requires special attention to different comorbidities that often are associated with hyperglycemia, such as overweight or obesity, dyslipidemia, hypertension, microvascular or macrovascular complications, etc. .. The control of these factors risk to health i...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：10.3305/nh.2013.28.sup2.6707
更新日期：2013-03-01 00:00:00
abstract：UNLABELLED:Head and neck cancer patients are frecuently heavy alcohol drinkers. The aim of this study is to determine the impact of alcohol intake on nutritional status and the impact in prognoses. PATIENTS AND METHODS:Fifty patients with oral and pharyngolaryngeal carcinomas were prospective studied in a control-case...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：
更新日期：2004-11-01 00:00:00
abstract：INTRODUCTION:Oxidative stress is one mechanism that could contribute to the acceleration of aging and age-related diseases. On the other hand, because of their antioxidative qualities soybean derived foods could have beneficial effects on the aging process. OBJECTIVES:The aim of our work was to study the effects of a ...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：
更新日期：2008-11-01 00:00:00
abstract：:Irritable bowel syndrome (IBS) is characterized by symptoms of abdominal pain and altered bowel habits. This common disorder is managed by varying clinical styles as no dominant therapeutic strategy has emerged. The pathophysiology of IBS remains unknown, but several lines of evidence link this disorder with the gut m...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章,评审
doi：10.3305/nh.2015.31.sup1.8713
更新日期：2015-02-07 00:00:00
abstract：:At our hospital, there is an At-Home Enteral Nutrition programme (NED in its Spanish acronym) with participation of the Clinical Nutrition Unit and the Pharmacy Service. The products and all necessary material are dispensed directly to the patient's home and nutritional follow-up is carried out. As a lack of informati...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：
更新日期：2003-11-01 00:00:00
abstract：UNLABELLED:Leptin is a peptidic hormone secreted by the fat tissue and plays an important role in body weight regulation. After menopause, weight gain increases as well as android-like obesity. Previous studies suggest a relationship between leptin level, body mass index (BMI) and fat distribution. OBJECTIVE:To establ...
journal_title：Nutricion hospitalaria
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
