Studies on oxidative stress induced nerve conduction deficits in cigarette smokers.

Abstract:

:An important role of oxidative stress for the development of vascular and neurological complications has encouraged us to undertake a study to assess the oxidative stress induced nerve conduction deficits among cigarette smokers. Eighteen regular male cigarette smokers and twenty nine male non-smokers were diagnosed for clinical neuro-physiological tests viz., motor and sensory nerve conduction velocity (MNCV and SNCV) and redox status. Significant depletion of reduced glutathione (GSH) level (p < 0.05) and significant increase in malondialdehyde (MDA) level (p < 0.01) was found in smokers compared to non-smokers. Motor and sensory nerve conduction velocity showed no significant difference among smokers compared to non-smokers. The present study shows that smoking can induce oxidative stress among smokers but could not exacerbate to nerve conduction deficits.

journal_name

J Environ Biol

authors

Singh VK,Pathak MK,Bihari V,Jyoti,Patel DK,Mathur N,Kesavachandran CN,Siddiqui MK

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

39-42

issue

1

eissn

0254-8704

issn

2394-0379

journal_volume

32

pub_type

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