Activity of the enzymes of the antioxidative system in cadmium-treated Oxya chinensis (Orthoptera Acridoidae).

Abstract:

:One purpose in this research was to determine the toxic effects of Cd on antioxidant enzymes of Oxya chinensis (Orthoptera: Acridoidae). Changes in the activities of the antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), and guaiacol peroxidase (GPx) were measured in O. chinensis insects injected with Cd(2+). Fifth-nymphs of O. chinensis insects were injected with Cd(2+) at different concentrations (0, 0.55×10(-4), 1.10×10(-4), 1.65×10(-4), 2.20×10(-4), and 2.75×10(-4)gg(-1)). An increase in SOD activity in O. chinensis was observed at 1.10×10(-4) to 2.75×10(-4)gg(-1) Cd(2+). The SOD activity was lower at 2.20×10(-4)and 2.75×10(-4)gg(-1) than that at 1.10×10(-4) and 1.65×10(-4)gg(-1). It appears that SOD had a positive protective effect at low Cd(2+) concentrations, and that this effect disappeared at high Cd(2+) concentrations. CAT activity was accelerated to varying degrees at 1.10×10(-4) to 2.75×10(-4)gg(-1) for males and at 1.10×10(-4), 2.20×10(-4), and 2.75×10(-4)gg(-1) for females. CAT showed a strong detoxification effect with all treatments. GPx activity decreased with increasing Cd(2+) concentration with all treatments for males and at 2.20×10(-4) and 2.65×10(-4)gg(-1) for females. We showed that GPx activity had a weak detoxification function with all treatments for males and at high Cd(2+) for females. Thus, CAT had a strong detoxification effect, whereas SOD had a medium and GPx had a weak detoxification effect. Among the three enzymes, CAT played an important role in the damaging mechanisms of reactive oxygen species in O. chinensis insects. Alterations of the antioxidant enzyme level under environmental stresses are suggested as indicators of biotic and abiotic stress.

authors

Lijun L,Xuemei L,Yaping G,Enbo M

doi

10.1016/j.etap.2005.04.001

subject

Has Abstract

pub_date

2005-11-01 00:00:00

pages

412-6

issue

3

eissn

1382-6689

issn

1872-7077

pii

S1382-6689(05)00093-1

journal_volume

20

pub_type

杂志文章
  • Activation of apoptotic pathway in normal, cancer ovarian cells by epothilone B.

    abstract::The epothilones, a new class of microtubule-targeting agents, seem to be a very promising alternative to the current strategy of cancer treatment. We have analyzed the aspects of epothilone B (Epo B) on cellular metabolism of tumor (OV-90) and normal (MM 14) ovarian cells. The observed effects were compared with those...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2013.06.003

    authors: Rogalska A,Szula E,Gajek A,Marczak A,Jóźwiak Z

    更新日期:2013-09-01 00:00:00

  • Microassay of superoxide anion scavenging activity in vitro.

    abstract::We have developed a photometric, platereader-based microassay for superoxide anion scavening activity in vitro. Superoxide anions were generated using a xanthine oxidase/hypoxanthine system and detected by following the reduction of ferricytochrome c at 550 nM. Inhibitory activity was assessed for superoxide dismutase...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/s1382-6689(96)00143-3

    authors: Laight DW,Andrews TJ,Haj-Yehia AI,Carrier MJ,Anggård EE

    更新日期:1997-02-15 00:00:00

  • Investigation of chronic toxicity of (14)C-fenitrothion and its degradation products on stored soybeans.

    abstract::Grains of soybeans were treated with the recommended dose of fenitrothion insecticide, 5mg/kg, and double that dose, before storage for 30 weeks under ambient local conditions. During the storage period, the penetration and distribution of insecticide residues were studied. The amount of surface residues on stored soy...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 信件

    doi:10.1016/j.etap.2008.08.005

    authors: Farghaly M,El-Maghraby S

    更新日期:2009-01-01 00:00:00

  • Regeneration of glutathione by α-lipoic acid via Nrf2/ARE signaling pathway alleviates cadmium-induced HepG2 cell toxicity.

    abstract::Alpha-lipoic acid (α-LA) is an important antioxidant that is capable of regenerating other antioxidants, such as glutathione (GSH). However, the underlying molecular mechanism by which α-LA regenerates GSH remains poorly understood. The current study aimed to investigate whether α-LA regenerates GSH by activation of N...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2017.02.022

    authors: Zhang J,Zhou X,Wu W,Wang J,Xie H,Wu Z

    更新日期:2017-04-01 00:00:00

  • The effect of Zataria multiflora on pulmonary function tests, hematological and oxidant/antioxidant parameters in sulfur mustard exposed veterans, a randomized doubled-blind clinical trial.

    abstract:BACKGROUND:Sulfur mustard is an alkylating agent which cause to short and long term incapacitations on various organs including lung. There is no definite treatment for lung disorders induced by SM exposure. In the present study, the preventive effect of Zataria multiflora (Z. multiflora) on hematological parameters, o...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.etap.2018.01.006

    authors: Khazdair MR,Rajabi O,Balali-Mood M,Beheshti F,Boskabady MH

    更新日期:2018-03-01 00:00:00

  • The protective role of vitamin E on gill and liver tissue histopathology and micronucleus frequencies in peripheral erythrocytes of Oreochromis niloticus exposed to deltamethrin.

    abstract::Deltamethrin, is a commonly used pyrethroid pesticide. Vitamin E is a antioxidant that plays an important role in protecting cells against toxicity by inactivating free radicals generated following pesticides exposure. Therefore, it was evaluated whether deltamethrin induced histopathological changes and nuclear abnor...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2012.03.009

    authors: Kan Y,Cengiz EI,Ugurlu P,Yanar M

    更新日期:2012-09-01 00:00:00

  • Effects of infrasound on hippocampus-dependent learning and memory in rats and some underlying mechanisms.

    abstract::To investigate the effect of infrasound on the hippocampus-dependent spatial learning and memory as well as its underlying mechanisms, we measured the changes of cognitive abilities, brain-derived neurotrophic factor (BDNF)-tyrosine kinase receptor B (TrkB) signal transduction pathway and neurogenesis in the hippocamp...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2009.04.011

    authors: Yuan H,Long H,Liu J,Qu L,Chen J,Mou X

    更新日期:2009-09-01 00:00:00

  • In utero exposure of neonatal buffalo calves to pesticide residues and the alterations within their reproductive tract.

    abstract::In utero exposure of neonates to pesticide residues could be damaging to the reproductive tract. Hence, the present study assessed the circulating concentrations of pesticide residues in buffalo and their neonatal calves as well as in the reproductive tract tissue samples of same calves. Also, histopathological altera...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2015.08.031

    authors: Kaur K,Ghuman SS,Singh O,Bedi JS,Gill JP

    更新日期:2015-11-01 00:00:00

  • The use of in vitro metabolic parameters and physiologically based pharmacokinetic (PBPK) modeling to explore the risk assessment of trichloroethylene.

    abstract::A physiologically based pharmacokinetic (PBPK) model has been developed for trichloroethylene (1,1,2-trichloroethene, TRI) for rat and humans, based on in vitro metabolic parameters. These were obtained using individual cytochrome P450 and glutathione S-transferase enzymes. The main enzymes involved both for rats and ...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/s1382-6689(02)00019-4

    authors: Hissink EM,Bogaards JJ,Freidig AP,Commandeur JN,Vermeulen NP,van Bladeren PJ

    更新日期:2002-07-01 00:00:00

  • Elevation of serum 17-beta-estradiol in channel catfish following injection of 17-beta-estradiol, ethynyl estradiol, estrone, estriol and estradiol-17-beta-glucuronide.

    abstract::17-beta-Estradiol is naturally converted in numerous organisms to various derivatives/metabolites, which may be excreted from the organism into its immediate external environment. There is a paucity of data regarding the biological effects of these derivatives/metabolites on aquatic organisms. Male channel catfish (20...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/s1382-6689(01)00062-x

    authors: Tilton F,Benson WH,Schlenk D

    更新日期:2001-03-01 00:00:00

  • Evaluation of antioxidant and antiulcerogenic activities of Opuntia ficus indica f. inermis flowers extract in rats.

    abstract::The Opuntia ficus indica f. inermis methanolic flowers extract (OMFE) was phytochemical studied, in vitro tested for their potential antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH), reducing power, linoleic acid peroxidation assays and in vivo evaluated for its ability to prevent ethanol-induced gastri...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2011.08.007

    authors: Alimi H,Hfaiedh N,Bouoni Z,Sakly M,Ben Rhouma K

    更新日期:2011-11-01 00:00:00

  • Polyphenolic fraction of Pilea microphylla (L.) protects Chinese hamster lung fibroblasts against γ-radiation-induced cytotoxicity and genotoxicity.

    abstract::Present study was designed to compare cytoprotective and antigenotoxic activity of the polyphenolic fraction of Pilea microphylla (PM1) with that of its active polyphenolic constituents against γ-radiation in V79 cells. PM1 was standardized with respect to the polyphenols present by RP-HPLC. It was evaluated for its f...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2011.09.007

    authors: Paul P,Bansal P,Nayak PG,Pannakal ST,Priyadarsini KI,Unnikrishnan MK

    更新日期:2012-01-01 00:00:00

  • Changes of respiratory system in mice exposed to PM4.0 or TSP from exhaust gases of combustion of cashew nut shell.

    abstract::Air pollution is a topic discussed all over the world and the search for alternatives to reduce it is of great interest to many researchers. The use of alternative energy sources and biofuels seems to be the environmentally safer solution. In this work, the deleterious effects on the respiratory system of mice exposed...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2017.08.020

    authors: Josino JB,Serra DS,Gomes MDM,Araújo RS,de Oliveira MLM,Cavalcante FSÁ

    更新日期:2017-12-01 00:00:00

  • Differential organ expression patterns of thyroid hormone receptor isoform genes in p,p'-DDE-treated adult male common frog, Rana temporaria.

    abstract::Using the European common frog, Rana temporaria, as a model, we have studied the organ-specific gene expression patterns of thyroid hormone receptor isoforms after exposure to an organochlorine (OC) compound, p,p'-DDE. Four groups of frogs were subcutaneously injected with p,p'-DDE at 0.01, 0.1, 1 and 10mg/kg body wei...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2005.05.008

    authors: Arukwe A,Jenssen BM

    更新日期:2005-11-01 00:00:00

  • Altered BRCA1 and BRCA2 responses and mutation of BRCA1 gene in mice exposed chronically and transgenerationally to aqueous extract of betel nut (AEBN).

    abstract::The Brca1 and Brca2 tumor suppressor genes are involved in the maintenance of genomic integrity as they facilitate error free DNA repair. This study was designed to understand the role of Brca1 and Brca2 in betel nut (BN) induced chronic and transgenerational carcinogenesis in mice. Young male and female Swiss Albino ...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2010.09.006

    authors: Choudhury Y,Sharan RN

    更新日期:2011-01-01 00:00:00

  • Biochemical and physiological biomarkers in Prochilodus lineatus submitted to in situ tests in an urban stream in southern Brazil.

    abstract::The aims of the present study were to verify the suitability of short-term in situ test with the neotropical fish Prochilodus lineatus and to evaluate from a set of biochemical and physiological biomarkers the ones which could work as sensitivity tools for the environmental quality assessment. In situ tests were carri...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2005.07.016

    authors: Camargo MM,Martinez CB

    更新日期:2006-01-01 00:00:00

  • Toxic effects of chlorpyrifos on antioxidant enzymes and target enzyme acetylcholinesterase interaction in mosquito fish, Gambusia affinis.

    abstract::The recovery effect of chlorpyrifos (CPF) on antioxidant enzymes, locomotor behaviour and the target enzyme acetylcholinesterase (AChE) interaction were studied after exposure to 297μgL(-1) (LC(50) for 96h) in mosquito fish, Gambusia affinis. Activities of the antioxidant enzymes-superoxide dismutase, catalase, glutat...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2008.03.010

    authors: Kavitha P,Rao JV

    更新日期:2008-09-01 00:00:00

  • Disruption of synaptic expression pattern and age-related DNA oxidation in a neuronal model of lead-induced toxicity.

    abstract::Lead (Pb) is recognized as a potent inducer of synaptic toxicity generally associated with reduced synaptic transmission and increased neuronal fiber excitability, becoming an environmental risk for neurodegenerative processes. Despite numerous toxicological studies on Pb have been directed to the developing brain, at...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2020.103350

    authors: Wu Z,Bai L,Tu R,Zhang L,Ba Y,Zhang H,Li X,Cheng X,Li W,Huang H

    更新日期:2020-05-01 00:00:00

  • Leaf and root extracts of Moricandia arvensis protect against DNA damage in human lymphoblast cell K562 and enhance antioxidant activity.

    abstract::Four extracts were prepared from the roots and leaves of Moricandia arvensis: root chloroform extract (ChlR), leaf chloroform extract (ChlL), root ethyl acetate extract (EAR) and leaf ethyl acetate extract (EAL). The genotoxic and antigenotoxic properties of these extracts were investigated by assessing the induction ...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2010.03.014

    authors: Skandrani I,Boubaker J,Bouhlel I,Limem I,Ghedira K,Chekir-Ghedira L

    更新日期:2010-07-01 00:00:00

  • Synergistic effect of non-ionic surfactants Tween 80 and PEG6000 on cytotoxicity of insecticides.

    abstract::The use of surfactants in the development of a suitable formulation for insecticides should improve the solubility behavior, the permeability and the efficiency against pests meanwhile decrease the toxic risks of insecticides on human health. Cytotoxicity of insecticides including abamectin, chlorfluazuron, hexaflumur...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2014.12.015

    authors: Li D,Wu X,Yu X,Huang Q,Tao L

    更新日期:2015-03-01 00:00:00

  • A new index to assess chemicals increasing the greenhouse effect based on their toxicity to algae.

    abstract::CO2, as the typical greenhouse gas causing the greenhouse effect, is a major global environmental problem and has attracted increasing attention from governments. Using algae to eliminate CO2, which has been proposed as an effective way to reduce the greenhouse effect in the past decades, can be disturbed by a growing...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2015.08.034

    authors: Wang T,Zhang X,Tian D,Gao Y,Lin Z,Liu Y,Kong L

    更新日期:2015-11-01 00:00:00

  • The influence of aripiprazole and olanzapine on neurotransmitters level in frontal cortex of prenatally stressed rats.

    abstract:OBJECTIVES:The study aims to verify whether alterations in the level of neurotransmitters have occurred in prenatally stressed rats (animal model of schizophrenia), and whether aripiprazole (ARI) and olanzapine (OLA) modify this level. METHODS:The effects of ARI (1.5mg/kg) and OLA (0.5mg/kg) were studied by means of m...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2016.07.007

    authors: Ratajczak P,Kus K,Gołembiowska K,Noworyta-Sokołowska K,Woźniak A,Zaprutko T,Nowakowska E

    更新日期:2016-09-01 00:00:00

  • Safrole induced cytotoxicity, DNA damage, and apoptosis in macrophages via reactive oxygen species generation and Akt phosphorylation.

    abstract::Safrole is a natural compound categorized as a group 2B carcinogen extracted from betel quid chewing, which is a common practice of psychoactive habits integrated into social and cultural ceremonies among serveral million people, especially in Southern or Southeastern Asia. Safrole is one of the major risk compunds fo...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2018.09.012

    authors: Chien KJ,Yang ML,Tsai PK,Su CH,Chen CH,Horng CT,Yeh CH,Chen WY,Lin ML,Chen CJ,Chian CY,Kuan YH

    更新日期:2018-12-01 00:00:00

  • Effect of low carbohydrate high protein (LCHP) diet on lipid metabolism, liver and kidney function in rats.

    abstract::The objective of this study was to compare effects of Western diet (WD) with low carbohydrate high protein (LCHP) diet on lipid metabolism, liver and kidney function in rats. Eighteen rats were randomly assigned to three experimental groups and fed for the next 2 months. The experimental diets were: Control (7% of soy...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2015.01.008

    authors: Kostogrys RB,Franczyk-Żarów M,Maślak E,Topolska K

    更新日期:2015-03-01 00:00:00

  • Effects of N-Butylphthalide on the expressions of Nogo/NgR in rat brain tissue after carbon monoxide poisoning.

    abstract::Carbon monoxide (CO) intoxication is one of the most common types of poisoning worldwide, and may result in neuropathologic sequelae, yet its pathogenesis is not clear and there is no optimal management strategy for patients with CO poisoning. In this study, the rat model of CO poisoning was established in a hyperbari...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2015.02.013

    authors: Li Q,Cheng Y,Bi MJ,Kang H,Qu Y,Lin H,Guo Y,Zou Y

    更新日期:2015-03-01 00:00:00

  • Genistein ameliorated endothelial nitric oxidase synthase uncoupling by stimulating sirtuin-1 pathway in ox-LDL-injured HUVECs.

    abstract::Endothelial nitric oxidase synthase (eNOS) uncoupling plays a causal role in endothelial dysfunction in atherosclerosis. Genistein consumption has been associated with the prevention of atherosclerosis. However, the effect of genistein on eNOS uncoupling has not been reported. A model of oxidized low-density lipoprote...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2016.01.011

    authors: Zhang HP,Zhao JH,Yu HX,Guo DX

    更新日期:2016-03-01 00:00:00

  • Characterization of phase-II conjugation reaction of polycyclic aromatic hydrocarbons in fish species: unique pyrene metabolism and species specificity observed in fish species.

    abstract::Metabolic activity, particularly conjugation, was examined in fish by analyzing pyrene (a four-ring, polycyclic aromatic hydrocarbon) metabolites using high-performance liquid chromatography (HPLC) with fluorescence detector (FD), a mass spectrometry (MS) system, and kinetic analysis of conjugation enzymes. Fourteen f...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2013.05.018

    authors: Ikenaka Y,Oguri M,Saengtienchai A,Nakayama SMM,Ijiri S,Ishizuka M

    更新日期:2013-09-01 00:00:00

  • Terephthalic acid occupational exposure and its effect on organ functions in fiber workers.

    abstract:OBJECTIVES:: To investigate the exposure to terephthalic acid (TPA), and to evaluate it's effects on organ function including the potential risk factors for uroliths and bladder tumor to TPA. METHODS:: Exposure-response modeling was carried out in a cohort of 141 TPA exposure workers and three subgroups were classifie...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2005.01.007

    authors: Dai G,Cui L,Song L,Gong N,Chen J,Zhao R,Wang S,Chang HC,Wang X

    更新日期:2005-07-01 00:00:00

  • Organophosphate-induced brain injuries: delayed apoptosis mediated by nitric oxide.

    abstract::The features of organophosphate-induced brain injuries were investigated. Rats were poisoned intraperitoneally with 9 mg/kg (1.8 LD(50)) of diisopropylfluorophosphate. Pyridostigmine bromide (0.1 mg/kg) and atropine methylnitrate (20 mg/kg), which are centrally inactive, were pre-treated intramuscularly to reduce the ...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/s1382-6689(99)00006-x

    authors: Kim YB,Hur GH,Shin S,Sok DE,Kang JK,Lee YS

    更新日期:1999-04-01 00:00:00

  • The mutagenic, DNA-damaging and antioxidative properties of bark and leaf extracts from Coutarea hexandra (Jacq.) K. Schum.

    abstract::Coutarea hexandra is a species commonly known in Brazil as quina, and its bark is used in folk medicine. In this study, we assess the mutagenic and DNA-damaging effects of ethanol extracts from C. hexandra stem bark (SCH) and leaves (LCH) by employing the Ames test on the TA98 and TA100 strains of Salmonella typhimuri...

    journal_title:Environmental toxicology and pharmacology

    pub_type: 杂志文章

    doi:10.1016/j.etap.2011.12.003

    authors: Nunes LG,Gontijo DC,Souza CJ,Fietto LG,Carvalho AF,Leite JP

    更新日期:2012-03-01 00:00:00