Abstract：
BACKGROUND:: Coughing is one of the chronic respiratory symptoms of patients exposed to sulfur mustard (SM) used against Iranian combatants and civilians by Iraq during the Iran-Iraq war, between 1983 and 1989. This study carried out on SM exposed patients who referred to our clinic because of exacerbation of chronic cough. METHOD:: Fifty male SM injured patient in the age range of 21-79 years, all of them having chronic bronchitis and were suffering from chronic cough (>3 weeks) were evaluated. After history taking and performing physical examination our diagnostic evaluation included chest X-ray, pulmonary function test (PFT), para nasal computerized tomography, esophageal endoscopy and fiber optic bronchoscopy. RESULTS:: Apart from having chronic bronchitis as a constant disease in all patients, the other main causative factors behind chronic cough were bronchospasm, post-nasal drip syndrome (PNDS), and gastro esophageal reflux disease (GERD), which accounted for 66%, 46% and 44% of chronic cough of the patients, respectively. A single cause for chronic cough was found in 4 patients (8%), 2 causes in 17 patients (34%), 3 causes in 23 patients (46%) and 4 causes in 6 patients (12%). CONCLUSION:: Since a high majority of the patients had more than a single cause for chronic cough, multiplicity of causes of chronic cough in a patient is indicative for evaluation of possible exposure to chemical fumes, especially SM. Because of high prevalence of chronic bronchitis (100%) and bronchospasm (66%) among our study group we conclude that they should be considered at first, before assessment of other causes.
journal_name
Environ Toxicol Pharmacoljournal_title
Environmental toxicology and pharmacologyauthors
Ghanei M,Hosseini AR,Arabbaferani Z,Shahkarami Edoi
10.1016/j.etap.2004.09.006subject
Has Abstractpub_date
2005-07-01 00:00:00pages
6-10issue
1eissn
1382-6689issn
1872-7077pii
S1382-6689(04)00183-8journal_volume
20pub_type
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