Abstract:
OBJECTIVE:The relationship between anxiety and impulsivity is controversial and not well explored. In a previous study we compared impulsivity, measured by different rating tools, in patients with anxiety disorders vs. healthy controls. In the same sample we now explore the influence of comorbid soft bipolar spectrum disorders on the relationship between anxiety disorders and impulsivity. METHOD:A sample including 47 subjects with anxiety disorder(s) and 45 control subjects matched for demographic, educational and work characteristics underwent a diagnostic evaluation by the Mini Neuropsychiatric Interview (MINI); a symptomatological evaluation by the Bech-Rafaelsen Depression and Mania Scale (BRDMS), the State-Trait Anxiety Inventory (STAI), the Hypomania Check List (HCL-32) and the Clinical Global Impression (CGI); a temperamental and personological evaluation by the Questionnaire for the Affective and Anxious Temperament Evaluation of Memphis, Pisa, Paris and San Diego-Modified (TEMPS-M), the Separation Anxiety Symptoms Inventory (SASI), the Interpersonal Sensitivity Symptoms Inventory (ISSI); and, finally, a psychometric and a neuro-cognitive evaluation of impulsivity by the Barratt Impulsiveness Scale (BIS) and the Immediate and Delayed Memory Task (IMT/DMT). The initial sample of patients with anxiety disorders was then subdivided into two subgroups depending on the presence of comorbid cyclothymia (Cyclo+, n=26 and Cyclo-, n=21). For the diagnosis of cyclothymic disorder, we used both the DSM-IV-TR criteria and also a modified threshold for hypomania with a duration of 2 days. We compared symptomatological, temperamental, personological and impulsivity measures in Cyclo+, Cyclo- and controls. RESULTS:The comparison between Cyclo+, Cyclo- and controls showed that Cyclo+ are the most impulsive subjects in all the investigated measures and are characterized by greatest symptomatological impairment, highest scores in temperamental scales, and highest levels of interpersonal sensitivity and separation anxiety. Cyclo- subjects resulted to be more impulsive compared to controls concerning the retrospective trait measures, but not in the neuro-cognitive test. LIMITATIONS:Correlational cross-sectional study. CONCLUSION:In our patients with anxiety disorders, without lifetime comorbidity with major mood episodes, trait and state impulsivity resulted to be greater than in controls. In particular impulsivity was highest in patients with both anxiety disorders and cyclothymia. In anxious-cyclothymic patients also separation anxiety and interpersonal sensitivity were more severe than in anxious patients without cyclothymia and controls. Our findings suggest that impulsivity, rather than being directly related to the presence of the anxiety disorder, could be associated with comorbidity with cyclothymia.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Perugi G,Del Carlo A,Benvenuti M,Fornaro M,Toni C,Akiskal K,Dell'Osso L,Akiskal Hdoi
10.1016/j.jad.2011.04.033subject
Has Abstractpub_date
2011-10-01 00:00:00pages
600-6issue
3eissn
0165-0327issn
1573-2517pii
S0165-0327(11)00200-Xjournal_volume
133pub_type
杂志文章abstract:BACKGROUND:Depressive Personality (DP) is being evaluated for future inclusion in DSM. One recurring issue has been conceptual and empirical redundancy with Dysthymia (i.e., Dysthymic Disorder; DD). METHODS:The symptom and syndrome overlap of DP and DD were tested in a clinical sample (N = 125) using both self-report ...
journal_title:Journal of affective disorders
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journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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journal_title:Journal of affective disorders
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.1016/j.jad.2008.03.020
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journal_title:Journal of affective disorders
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.08.068
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journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2006.09.037
更新日期:2007-06-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.06.021
更新日期:2013-10-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/j.jad.2008.06.002
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:The personality trait of Persistence is highly valued by conscientious overachievers, but it has both psychological costs and benefits. The interactions among multiple personality factors influencing the development of mood and anxiety disorders have been confounded in prior clinical samples, but can be dise...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.09.046
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Late-life depression is associated with premature mortality, however, little is known whether excess mortality rates of depression have changed over time. This study aims to identify and explain secular trends in excess mortality of major depressive disorder (MDD) and subthreshold depression (SUBD). METHODS...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.02.068
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journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2003-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/0165-0327(92)90091-j
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