Extraneural metastases in medulloblastoma.

Abstract:

:Medulloblastoma is the most common childhood malignant tumor of central nervous system, but it may also occur in adults. It presents high invasive growth with spreading of tumor cells into the leptomeningeal space along the neuroaxis early in the course of the disease. Extraneural metastases are rare but frequently lethal, occurring only in 1 to 5% of patients, and are related, in the most of cases, to the presence of ventriculoperitoneal shunt. Here we characterize the clinical profile of five cases of medulloblastoma with systemic spreading of tumor cells, also comparing them to cases already described in the literature.

journal_name

Arq Neuropsiquiatr

authors

Muoio VM,Shinjo SO,Matushita H,Rosemberg S,Teixeira MJ,Marie SK

doi

10.1590/s0004-282x2011000300012

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

328-31

issue

2B

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2011000300012

journal_volume

69

pub_type

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