Abstract:
:Hormones are dynamically collected by fenestrated capillaries to generate pulses, which are then decoded by target tissues to mount a biological response. To generate hormone pulses, endocrine systems have evolved mechanisms to tightly regulate blood perfusion and oxygenation, coordinate endocrine cell responses to secretory stimuli, and regulate hormone uptake from the perivascular space into the bloodstream. Based on recent findings, we review here the mechanisms that exist in endocrine systems to regulate blood flow, and facilitate coordinated cell activity and output under both normal physiological and pathological conditions in the pituitary gland and pancreas.
journal_name
J Mol Endocrinoljournal_title
Journal of molecular endocrinologyauthors
Schaeffer M,Hodson DJ,Lafont C,Mollard Pdoi
10.1530/JME-11-0035subject
Has Abstractpub_date
2011-08-25 00:00:00pages
R59-66issue
2eissn
0952-5041issn
1479-6813pii
JME-11-0035journal_volume
47pub_type
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