Scoring system development and validation for initial treatment failure in suppurative kidney infections.

Abstract:

BACKGROUND:Suppurative kidney infections (SKIs) have potentially lethal implications and a high incidence of treatment-related morbidity and death. Until this point, there has been no study that has derived a prognostic model for adverse early outcomes in SKI. Therefore, our aim was to derive and validate a simple scoring system of early treatment failure in SKI. METHODS:Logistic regression and bootstrap methods were used to create an integer score for estimating the risk of early treatment failure using patient characteristics, severity of disease, bacterial etiology, type of pathology, initial antibiotic therapy, and early urologic procedures. RESULTS:This study included 92 adult patients with 104 SKIs. Early treatment failure was observed in 57 patients (54.8%). The length of the hospital stay and the treatment complications were significantly longer and more common, respectively, in patients with early treatment failure. The factors associated most strongly with early treatment outcome were whether there had been an early complete urologic procedure, the adequacy of early antibiotic therapy, and the presence or absence of sepsis syndrome. The total possible score ranged from 0 to 22 points, with a cut-off value of 5 points. A score of ≤ 5 points identified early success correctly in 85.3% of patients, whereas a score > 5 points correctly identified early failure in 93.2%. The scoring system retained its predictive ability on the validation set. CONCLUSION:A scoring system was created to predict early treatment failure for a given patient with SKI. Although the system has good performance characteristics and provides a possible intervention measure, further studies should be performed before widespread implementation.

journal_name

Surg Infect (Larchmt)

journal_title

Surgical infections

authors

Stojadinović MM,Milovanović DR,Gajić BS

doi

10.1089/sur.2010.057

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

119-25

issue

2

eissn

1096-2964

issn

1557-8674

journal_volume

12

pub_type

杂志文章
  • Pyomyositis: Are We Missing the Diagnosis?

    abstract:BACKGROUND:Pyomyositis (PY) is a primary infection of the skeletal muscles, leading to inflammation of the muscle fibers followed by pus formation and even necrosis in late stages. Because of overlap in presentation of intermuscular abscess (IM) and PY, the exact incidence and severity of PY is under-appreciated. PATI...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2015.191

    authors: Agarwal N,Aroor S,Saini P,Gupta A,Kaur N

    更新日期:2016-10-01 00:00:00

  • Endotracheal intubation: the role of sterility.

    abstract:BACKGROUND:There is a paucity of data regarding whether sterile handling of endotracheal tubes (ETTs) impacts the incidence and prevalence of pneumonia in the emergency, urgent, or elective clinical scenarios. Intensive care units employ infection control and reduction schemes to reduce pneumonia rates. METHODS:A MEDL...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2006.054

    authors: Cheung N,Betro G,Luckianow G,Napolitano L,Kaplan LJ

    更新日期:2007-10-01 00:00:00

  • Surgical Site Infections after Open Reduction Internal Fixation for Trauma in Low and Middle Human Development Index Countries: A Systematic Review.

    abstract:BACKGROUND:Musculoskeletal trauma represents a large source of morbidity in low and middle human development index countries (LMHDICs). Open reduction and internal fixation (ORIF) of traumatic long bone fractures definitively manages these injuries and restores function when conducted safely and effectively. Surgical s...

    journal_title:Surgical infections

    pub_type: 杂志文章,meta分析,评审

    doi:10.1089/sur.2017.273

    authors: McQuillan TJ,Cai LZ,Corcoran-Schwartz I,Weiser TG,Forrester JD

    更新日期:2018-04-01 00:00:00

  • Basic aspects of and general problems in surgical infections.

    abstract::Antibiotics are important in the prophylaxis and treatment of surgical infections as well as in the management of nosocomial infections acquired postoperatively in surgical patients. Surgeons encounter a range of infectious conditions, including established single-pathogen infections of soft tissues, polymicrobial int...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2001.2.s1-3

    authors: Fry DE

    更新日期:2001-01-01 00:00:00

  • Nucleated red blood cells are associated with a higher mortality rate in patients with surgical sepsis.

    abstract:BACKGROUND:Nucleated red blood cells (NRBCs) are present in certain non-oncologic disease states and are associated with a poor prognosis. The purpose of this study was to evaluate NRBCs as an early prognostic marker for death in patients with surgical sepsis. METHODS:Retrospective evaluation of data collected prospec...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2011.089

    authors: Desai S,Jones SL,Turner KL,Hall J,Moore LJ

    更新日期:2012-12-01 00:00:00

  • Use of Cidofovir for Cytomegalovirus Disease Refractory to Ganciclovir in Solid Organ Recipients.

    abstract:BACKGROUND:Solid organ transplantation (SOT) frequently is complicated by cytomegalovirus (CMV) infections. Cidofovir (CDV) is active against CMV, including many ganciclovir (GCV)-resistant mutants, but often is considered to be too nephrotoxic for use after organ transplantation. PATIENTS AND METHODS:Seven males and ...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2015.266

    authors: Bonatti H,Sifri CD,Larcher C,Schneeberger S,Kotton C,Geltner C

    更新日期:2017-02-01 00:00:00

  • Impact of Body Mass Index and Bacterial Resistance in Osteomyelitis after Antibiotic Prophylaxis of Open Lower-Extremity Fractures.

    abstract:BACKGROUND:We investigated the clinical effectiveness of antimicrobial prophylaxis in lower-extremity open fractures following the Eastern Association for the Surgery of Trauma Guidelines. METHODS:This observational, retrospective, single-center study included adults with lower-extremity open fractures of the ankle, t...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2016.219

    authors: Bremmer D,Bookstaver B,Cairns M,Lindley K,Durkin M,Koon D,Quidley AM

    更新日期:2017-04-01 00:00:00

  • Analysis of plasma citrulline and intestinal morphometry in mice with hepatosplenic schistosomiasis.

    abstract:BACKGROUND:Portal hypertension in the mucosa of the intestine and the presence of granulomas in the wall of this organ can alter digestive function in patients with schistosomiasis. Citrulline is a potential marker of intestinal function in some diseases that affect the morphometry of the mucosa because of its close as...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2009.066

    authors: Siqueira LT,Ferraz AA,Campos JM,De Lima Filho JL,Albuquerque MC,de Lima Aires A,Ribeiro MH,Cavalcanti MT,De Lima B Cavalcanti C,Ferraz EM

    更新日期:2010-10-01 00:00:00

  • Daptomycin-associated eosinophilic pneumonia in two patients with prosthetic joint infection.

    abstract:BACKGROUND:Daptomycin is used increasingly to treat prosthetic joint infection (PJI). A possible side effect of this drug is eosinophilic pneumonia. We describe two patients with PJI treated with daptomycin who had this side effect with different clinical presentations. METHODS:Case reports and review of the literatur...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2013.200

    authors: Yusuf E,Perrottet N,Orasch C,Borens O,Trampuz A

    更新日期:2014-12-01 00:00:00

  • Positive sterility cultures of transplant solutions during pancreatic islet autotransplantation are associated infrequently with clinical infection.

    abstract:BACKGROUND:Chronic pancreatitis is a painful and often debilitating disease. Total pancreatectomy with intra-portal islet autotransplantation (TP-IAT) is a treatment option that allows for pain relief and preservation of beta-cell mass, thereby minimizing the complication of diabetes mellitus. Cultures of harvested isl...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2013.224

    authors: Colling KP,Blondet JJ,Balamurugan AN,Wilhelm JJ,Dunn T,Pruett TL,Sutherland DE,Chinnakotla S,Bellin M,Beilman GJ

    更新日期:2015-04-01 00:00:00

  • Pre-hospital intubation factors and pneumonia in trauma patients.

    abstract:BACKGROUND:We reported similar rates of ventilator-associated pneumonia (VAP) previously in trauma patients intubated either in a pre-hospital (PH) venue or the emergency department. A subset of PH intubations with continuous quality assessment was re-examined to identify the intubation factors associated with VAP. ME...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2010.074

    authors: Evans HL,Warner K,Bulger EM,Sharar SR,Maier RV,Cuschieri J

    更新日期:2011-10-01 00:00:00

  • Albumin/Procalcitonin Ratio Is a Sensitive Early Marker of Nosocomial Blood Stream Infection in Patients with Intra-Cerebral Hemorrhage.

    abstract:: Background: This study was performed to investigate the combination of admission serum procalcitonin (PCT) and albumin (alb) concentrations as a diagnostic predictor for discriminating patients with nosocomial blood stream infection (BSI) among those with spontaneous intra...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2018.260

    authors: Deng S,Gao J,Zhao Z,Tian M,Li Y,Gong Y

    更新日期:2019-12-01 00:00:00

  • Can Nasal Methicillin-Resistant Staphylococcus aureus Screening Be Used to Avoid Empiric Vancomycin Use in Intra-Abdominal Infection?

    abstract:BACKGROUND:Vancomycin is used widely as empiric therapy for gram-positive organisms in patients with an intra-abdominal infection (IAI), even in those with no history of methicillin-resistant Staphylococcus aureus (MRSA) infection or colonization. Potential adverse effects of vancomycin include nephrotoxicity, increase...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2014.211

    authors: Hennessy SA,Shah PM,Guidry CA,Davies SW,Hranjec T,Sawyer RG

    更新日期:2015-08-01 00:00:00

  • Outcomes of operative management of appendicitis.

    abstract:BACKGROUND:There has not been an appraisal of outcomes of appendectomy for more than 10 years. More reliable diagnostic techniques and minimally invasive surgery are now in widespread use, yet the impact of these advances remains unknown. METHODS:A retrospective review was performed of 453 patients who underwent appen...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2011.104

    authors: Dhupar R,Evankovich J,Ochoa JB,Vargas LG,Hughes SJ

    更新日期:2012-06-01 00:00:00

  • Tubercular temporalis abscess with skull and dural invasion.

    abstract:BACKGROUND:Mycobacterium tuberculosis infection rarely penetrates both skull and dura with temporalis muscle abscess formation. METHODS:Case report and review of the literature. RESULTS:A non-immunocompromised female patient with a right temporal mass underwent surgical resection. The tubercular abscess extended from...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2012.106

    authors: Yan JL,Wei KC

    更新日期:2013-10-01 00:00:00

  • The role of beta-lactam antimicrobials as single agents in treatment of intra-abdominal infection.

    abstract::Broad-spectrum beta-lactam antibiotics have several advantages in the treatment of intra-abdominal infections. These agents are effective against gram-negative rods and anaerobes, reach therapeutic levels rapidly after parenteral administration, and, in the absence of penicillin allergy, generally exhibit low toxicity...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/109629600321308

    authors: Powell LL,Wilson SE

    更新日期:2000-01-01 00:00:00

  • Primary orbital hydatid cyst in an elderly patient.

    abstract:BACKGROUND:Orbital hydatidosis is rare, accounting for only 1% of all hydatid cysts. Herein we report a case and review the sparse literature. METHODS:Case report and review of pertinent literature. RESULTS:A 74-year-old farmer presented with progressive proptosis and loss of vision of the left eye. Evaluation reveal...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2009.019

    authors: Limaiem F,Bellil S,Bellil K,Chelly I,Mekni A,Khaldi M,Haouet S,Kchir N,Zitouna M

    更新日期:2010-08-01 00:00:00

  • Acellular dermal matrix compared with synthetic implant material for repair of ventral hernia in the setting of peri-operative Staphylococcus aureus implant contamination: a rabbit model.

    abstract:BACKGROUND:Implant infection is a common clinical complication of abdominal hernia repair. Our objectives were to determine if acellular dermal matrix (ADM) grafts resisted Staphylococcus aureus infection better (as measured by ability to reduce or clear bacterial counts) than synthetic (polytetrafluoroethylene [PTFE])...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2007.044

    authors: Milburn ML,Holton LH,Chung TL,Li EN,Bochicchio GV,Goldberg NH,Silverman RP

    更新日期:2008-08-01 00:00:00

  • Adrenergic modulation of erythropoiesis following severe injury is mediated through bone marrow stroma.

    abstract:BACKGROUND:Severe trauma leads to hematopoietic failure and bone marrow (BM) dysfunction that manifests clinically as a persistent anemia and leukopenia. The impact of severe trauma and its associated hyperadrenergic state on erythropoiesis has not been described. The aim of this study was to demonstrate the effects of...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2004.5.385

    authors: Fonseca RB,Mohr AM,Wang L,Clinton E,Sifri ZC,Rameshwar P,Livingston DH

    更新日期:2004-01-01 00:00:00

  • The Surviving Sepsis Campaign: a history and a perspective.

    abstract:BACKGROUND:The Surviving Sepsis Campaign (SSC) was launched in 2002 as a collaborative initiative of the European Society of Intensive Care Medicine (ESICM), the International Sepsis Forum (ISF), and the Society of Critical Care Medicine (SCCM). Its objective was, through the development and promulgation of evidence-ba...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2010.024

    authors: Marshall JC,Dellinger RP,Levy M

    更新日期:2010-06-01 00:00:00

  • Comprehensive Approach to Reduce Surgical Site Infections in Patients Undergoing Neurosurgical Procedures.

    abstract:: Background: Surgical site infections (SSIs) are recognized complications of surgical procedures. Methicillin-resistant Staphylococcus aureus (MRSA) colonization increases the likelihood of developing SSIs. Decolonization of MRSA has been shown to reduce post-operative SSIs...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2020.020

    authors: Nusair AR,El Nekidy WS,Reynolds L,Evans D,El-Lababidi R,Alatoom A

    更新日期:2020-05-04 00:00:00

  • High Number of Door Openings Increases the Bacterial Load of the Operating Room.

    abstract:: Background: Operating room (OR) traffic and door openings have emerged as potential modifiable risk factors for the development of surgical site infections. Methods: This study compared the microbial load of a Control OR withou...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2020.361

    authors: Lansing SS,Moley JP,McGrath MS,Stoodley P,Chaudhari AMW,Quatman CE

    更新日期:2020-12-23 00:00:00

  • Incidence and Risk Factors Associated with Multi-Drug-Resistant Pathogens in a Critically Ill Trauma Population: A Retrospective Cohort Study.

    abstract:: Background: Multi-drug resistance is considered a serious health threat particularly in the intensive care unit (ICU) setting. Studies evaluating multi-drug-resistant (MDR) pathogens in critically ill trauma patients are limited. The objectives were to describe the inciden...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2019.031

    authors: Cucci M,Wooten C,Fowler M,Mallat A,Hieb N,Mullen C

    更新日期:2020-02-01 00:00:00

  • Influence of bronchoscopy on the diagnosis of and outcomes from ventilator-associated pneumonia.

    abstract:BACKGROUND:Ventilator-associated pneumonia (VAP) is a common healthcare-associated infection affecting as many as 27% of mechanically ventilated patients. Ventilator-associated pneumonia is an important source of morbidity and mortality in the surgical intensive care unit (SICU). The optimal diagnostic method for VAP h...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2013.142

    authors: Guidry CA,Mallicote MU,Petroze RT,Hranjec T,Rosenberger LH,Davies SW,Sawyer RG

    更新日期:2014-10-01 00:00:00

  • Hand infections: basic principles and management.

    abstract:BACKGROUND:An untreated hand infection can lead rapidly to tissue destruction and permanent disability. METHODS:Review of the pertinent English literature. RESULTS:Early diagnosis and timely, effective intervention is crucial to treatment. Anatomically, the hand consists of multiple potential spaces and tissue planes...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2004.5.210

    authors: Spann M,Talmor M,Nolan WB

    更新日期:2004-07-01 00:00:00

  • Surgical site infections and the surgical care improvement project (SCIP): evolution of national quality measures.

    abstract:BACKGROUND:Surgical site infection (SSI) continues to be a common if often times preventable infection. Considerable patient morbidity and economic cost are the consequences. METHODS:Review of the pertinent English-language literature. RESULTS:The National Surgical Infection Prevention (SIP) Project was an initiative...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2008.9951

    authors: Fry DE

    更新日期:2008-12-01 00:00:00

  • Treating Surgical Infections in Low- and Middle-Income Countries: Source Control, Then What?

    abstract::Surgical infections present a significant burden of disease globally. Management focuses on source control and appropriate antibiotic therapy. This remains a challenge in low- and middle-income settings, where access to surgical care and antibiotics is limited. This paper discusses the complex challenges facing the ma...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2018.125

    authors: Rickard J

    更新日期:2019-04-01 00:00:00

  • Infection Rates after Periocular Surgery Utilizing New versus Re-Processed Monopolar Electrocautery.

    abstract:BACKGROUND:To determine if there is a difference in periocular post-operative infection rates when utilizing new versus re-processed monopolar electrocautery tips. METHODS:Retrospective cohort study of 4,976 consecutive surgical cases involving 17,149 procedures. Post-operative infections were identified using chart r...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2014.055

    authors: Czyz CN,Abramowitz BD,Goodman AE,Foster JA,Cahill KV,Everman KR

    更新日期:2015-06-01 00:00:00

  • Infective complications in laparoscopic surgery.

    abstract:BACKGROUND AND PURPOSE:One of the main benefits of minimally invasive surgery compared with open surgery is the significant reduction in the incidence of postoperative infections. Possible explanations include the smaller incision, minimal use of central venous catheters for parenteral nutrition, faster mobilization, r...

    journal_title:Surgical infections

    pub_type: 杂志文章,评审

    doi:10.1089/sur.2006.7.s2-109

    authors: Boni L,Benevento A,Rovera F,Dionigi G,Di Giuseppe M,Bertoglio C,Dionigi R

    更新日期:2006-01-01 00:00:00

  • Awareness of Practice and Comparison with Best Evidence in Surgical Site Infection Prevention in Colorectal Surgery.

    abstract:: Background: The use of mechanical bowel preparation and prophylaxis with oral antimicrobial agents can prevent surgical site infection (SSI) in colorectal surgical procedures, but routine adoption of these and other practices by surgeons has been limited. The aim of this s...

    journal_title:Surgical infections

    pub_type: 杂志文章

    doi:10.1089/sur.2019.203

    authors: Badia JM,Casey AL,Rubio-Pérez I,Arroyo-García N,Espin E,Biondo S,Balibrea JM

    更新日期:2020-04-01 00:00:00