Determination of antidermatophytic effects of non-steroidal anti-inflammatory drugs on Trichophyton mentagrophytes and Epidermophyton floccosum.

Abstract:

:Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most common pharmacological agents. They have three primary therapeutic properties including anti-inflammatory, anti-pyretic and analgesic effects. Seven NSAIDs were tested against two species of dermatophytes. Percentage inhibition was determined for effective agents. Diclofenac, aspirin and naproxen showed more potential to inhibit the growth of dermatophytes. Epidermophyton floccosum revealed susceptibility to more number of the tested agents than Trichophyton mentagrophytes. In conclusion, many NSAIDs may have a high potential to inhibit the growth of dermatophytes, while some of the agents belonging to this pharmaceutical group used in this study showed a potential activity on tested fungi.

journal_name

Mycoses

journal_title

Mycoses

authors

Al-Janabi AA

doi

10.1111/j.1439-0507.2010.01945.x

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

e443-8

issue

5

eissn

0933-7407

issn

1439-0507

journal_volume

54

pub_type

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