Abstract:
:To assess the incidence of and risk factors for clinical and subclinical dengue virus (DENV) infection, we prospectively studied 1,207 adult short-term travelers from the Netherlands to dengue-endemic areas. Participants donated blood samples for serologic testing before and after travel. Blood samples were tested for antibodies against DENV. Seroconversion occurred in 14 (1.2%) travelers at risk. The incidence rate was 14.6 per 1,000 person-months. The incidence rate was significantly higher for travel during the rainy months. Dengue-like illness occurred in 5 of the 14 travelers who seroconverted. Seroconversion was significantly related to fever, retro-orbital pain, myalgia, arthralgia, and skin rash. The risk for DENV infection for short-term travelers to dengue-endemic areas is substantial. The incidence rate for this study is comparable with that in 2 other serology-based prospective studies conducted in the 1990s.
journal_name
Emerg Infect Disjournal_title
Emerging infectious diseasesauthors
Baaten GG,Sonder GJ,Zaaijer HL,van Gool T,Kint JA,van den Hoek Adoi
10.3201/eid1705.101125subject
Has Abstractpub_date
2011-05-01 00:00:00pages
821-8issue
5eissn
1080-6040issn
1080-6059journal_volume
17pub_type
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