当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Physical properties of mesenchymal stem cells are coordinated by the perinuclear actin cap.

Physical properties of mesenchymal stem cells are coordinated by the perinuclear actin cap.

Abstract：

:Mesenchymal stem cells (MSCs) have been extensively investigated for their applications in regenerative medicine. Successful use of MSCs in cell-based therapies will rely on the ability to effectively identify their properties and functions with a relatively non-destructive methodology. In this study, we measured the surface stiffness and thickness of rat MSCs with atomic force microscopy and clarified their relation at a single-cell level. The role of the perinuclear actin cap in regulating the thickness, stiffness, and proliferative activity of these cells was also determined by using several actin cytoskeleton-modifying reagents. This study has helped elucidate a possible link between the physical properties and the physiological function of the MSCs, and the corresponding regulatory role of the actin cytoskeleton.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Kihara T,Haghparast SM,Shimizu Y,Yuba S,Miyake J

doi

10.1016/j.bbrc.2011.04.022

subject

Has Abstract

pub_date

2011-05-27 00:00:00

pages

1-6

issue

1

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(11)00585-7

journal_volume

409

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Atrial natriuretic peptide regulation of endothelial permeability is mediated by cGMP.

    abstract：:Previous studies in our laboratory showed that ANP inhibits increases in endothelial monolayer permeability to macromolecules induced by thrombin. In this present study, we investigated the second messenger system involved in the influence of ANP on monolayer permeability. In bovine aortic endothelial cells (BAEC), AN...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(90)90744-8

    authors： Lofton CE,Newman WH,Currie MG

    更新日期：1990-10-30 00:00:00

  • Selective inhibition of NADH-CoQ oxidoreductase (complex I) of rat brain mitochondria by arachidonic acid.

    abstract：:The effects of arachidonic acid on the enzyme complexes in the electron transport system were investigated using submitochondrial particles from rat brain. Arachidonic acid irreversibly inhibited NADH-CoQ oxidoreductase (complex I) activity, but had no effect on the activities of succinate-CoQ oxidoreductase (complex ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)91008-z

    authors： Morii H,Takeuchi Y,Watanabe Y

    更新日期：1991-08-15 00:00:00

  • Heterooligomers of the muscarinic receptor and G proteins purified from porcine atria.

    abstract：:Muscarinic receptor extracted from porcine atria in digitonin-cholate copurified with Galpha(o), Galpha(i1-3), and caveolins. The presence of complexes was confirmed by coimmunoprecipitation of the receptor, alpha-subunits, and caveolins in various combinations. Homooligomers of alpha(i2) were detected on Western blot...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.06.105

    authors： Ma AW,Pawagi AB,Wells JW

    更新日期：2008-09-12 00:00:00

  • VASP involvement in force-mediated adherens junction strengthening.

    abstract：:Strengthening of cell-matrix adhesions in response to applied force has been well documented. However, while implied by various lines of evidence, the force-mediated strengthening of cell-cell adhesions has not been directly demonstrated. In the current study, we present results consistent with force strengthening in ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.07.132

    authors： Kris AS,Kamm RD,Sieminski AL

    更新日期：2008-10-10 00:00:00

  • Anti-adipogenic effects of sesamol on human mesenchymal stem cells.

    abstract：:Human mesenchymal stem cells (hMSCs) from adult bone marrow are able to differentiate into adipocytes, osteoblasts, chondrocytes and neuronal cells. Adipocytes in bone marrow are primarily responsible for the maintenance of bone structure by maintaining cell number balance with other stromal cells. However, the number...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.11.070

    authors： Kim M,Lee YJ,Jee SC,Choi I,Sung JS

    更新日期：2016-01-01 00:00:00

  • Mapping of the MRPm5 epitope to the cytosolic region between transmembrane helices 13 and 14 in the drug and organic anion transporter, MRP1 (ABCC1).

    abstract：:Multidrug resistance in human tumour cells is often associated with increased expression of the 190kDa multidrug resistance protein, MRP1, that belongs to the ATP-binding cassette superfamily of transport proteins. MRP1 is also an efficient transporter of many organic anions. In the present study, we have mapped the e...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.01.111

    authors： Koike K,Deeley RG,Cole SP

    更新日期：2004-03-12 00:00:00

  • Glucose tolerance factor stimulates 3-O-methylglucose transport into isolated rat adipocytes.

    abstract：:Glucose tolerance factor partially purified from yeast extract powder stimulated [U-14C]-D-glucose uptake to a level 5.6 times greater than the basal level in the absence of insulin in isolated adipocytes prepared from rats fed with normal laboratory chow. The factor also stimulated 3-O-methylglucose transport 2.2-fol...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(87)91443-4

    authors： Tokuda M,Kashiwagi A,Wakamiya E,Oguni T,Mino M,Kagamiyama H

    更新日期：1987-05-14 00:00:00

  • Cloning and characterization of the 5'-flanking region for the mouse phospholipase C-delta1 gene.

    abstract：:To date, little is known about the molecular mechanisms controlling the regulation of phospholipase C-delta1 (PLC-delta1) gene expression. To understand the mechanisms responsible for the regulation of PLC-delta1 gene expression, the 5'-flanking region of the mouse PLC-delta1 gene was isolated from a mouse genomic DNA...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.2930

    authors： Kim JK,Lee WK,Nam HW,Lee KH,Han H,Rha HK,Jun TY,Kim KS,Choi CR

    更新日期：2000-06-24 00:00:00

  • Inhibition of cytochrome P-450-linked monooxygenase systems by naphthoquinones.

    abstract：:Several naphthoquinones, except 2-hydroxy-1,4-naphthoquinone, were found to inhibit microsomal cytochrome P-450-linked monooxygenase activities in rabbit liver and human placenta. In particular, 5-hydroxy-1,4-naphthoquinone inhibited placental estrogen biosynthesis more effectively than it did hepatic drug oxidation r...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(87)90555-9

    authors： Muto N,Inouye K,Inada A,Nakanishi T,Tan L

    更新日期：1987-07-31 00:00:00

  • Histone H1-stimulated phosphorylase phosphatase from rabbit skeletal muscle.

    abstract：:A major rabbit skeletal muscle phosphorylase phosphatase activity which is markedly stimulated by histone H1 has been resolved from inhibitor-sensitive phosphorylase phosphatase (type-1 phosphatase), glycogen synthase kinase 3-activated phosphatase, phosphatase heat-stable inhibitor proteins, and alkaline phosphatase ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(83)91228-7

    authors： Mellgren RL,Schlender KK

    更新日期：1983-12-16 00:00:00

  • Aldosterone promotes fibronectin production through a Smad2-dependent TGF-beta1 pathway in mesangial cells.

    abstract：:Accumulating evidence demonstrates that aldosterone can cause extra-cellular matrix (ECM) accumulation, in addition to regulating sodium and potassium homeostasis. Increased extra-cellular matrix production by renal glomerular mesangial cells has been suggested to be involved in pathogenesis of glomerular sclerosis. T...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.07.057

    authors： Lai L,Chen J,Hao CM,Lin S,Gu Y

    更新日期：2006-09-15 00:00:00

  • Sequence homology between prokaryotic and eukaryotic forms of serine hydroxymethyltransferase.

    abstract：:The sequence of tryptic and chymotryptic peptides from cytosolic and mitochondrial rabbit liver serine hydroxymethyltransferase are compared to the proposed sequence of a protein coded for by the glyA gene of Escherichia coli. The E. coli glyA gene is believed to code for serine hydroxymethyltransferase. Extensive seq...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(83)80242-3

    authors： Barra D,Martini F,Angelaccio S,Bossa F,Gavilanes F,Peterson D,Bullis B,Schirch L

    更新日期：1983-11-15 00:00:00

  • Methylthioadenosine and polyamine biosynthesis in a Saccharomyces cerevisiae meu1delta mutant.

    abstract：:As part of our studies on polyamine biosynthesis in yeast, the metabolism of methylthioadenosine was studied in a mutant that lacks methylthioadenosine phosphorylase (meu1delta). The nucleoside accumulates in this mutant and is mainly excreted into the culture medium. Intracellular accumulation of the nucleoside is en...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.02.144

    authors： Chattopadhyay MK,Tabor CW,Tabor H

    更新日期：2006-04-28 00:00:00

  • Involvement of a chromatin modifier in response to mono-(2-ethylhexyl) phthalate (MEHP)-induced Sertoli cell injury: probably an indirect action via the regulation of NFκB/FasL circuitry.

    abstract：:The Fas/FasL signaling pathway, controlled by nuclear factor-κB (NFκB) at the transcriptional level, is critical for triggering germ cell apoptosis in response to mono-(2-ethylhexyl) phthalate (MEHP)-induced Sertoli cell (SC) injury, but the exact regulation mechanism remain unknown. Here, we discovered that expressio...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2013.09.135

    authors： Chen S,Dong Y,Xu C,Jiang L,Chen Y,Jiang C,Hou W,Li W

    更新日期：2013-11-01 00:00:00

  • Prosomatostatin II processing is initiated in the trans-Golgi network of anglerfish pancreatic cells.

    abstract：:Anglerfish prosomatostatin II, the precursor of somatostatin-28 II, is produced in different cells from prosomatostatin I, by a cleavage at Arg73. Antibodies were raised against the carboxy-terminal [64-72] portion of the precursor II upstream from somatostatin-28 II sequence. These antibodies recognized only this epi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(90)90530-z

    authors： Bourdais J,Devilliers G,Girard R,Morel A,Benedetti L,Cohen P

    更新日期：1990-08-16 00:00:00

  • Oxidation of alpha1-proteinase inhibitor by the myeloperoxidase-hydrogen peroxidase system promotes binding to immunoglobulin A.

    abstract：:We have demonstrated previously that patients with rheumatoid arthritis (RA) show an increase in serum and synovial fluid levels of complexes between alpha1-proteinase inhibitor (alpha1PI) and IgA. These are believed to form through disulfide binding between the Cys232 residue on alpha1PI and the penultimate cysteine ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1999.0247

    authors： Scott LJ,Russell GI,Nixon NB,Dawes PT,Mattey DL

    更新日期：1999-02-24 00:00:00

  • The Tax oncogene enhances ELL incorporation into p300 and P-TEFb containing protein complexes to activate transcription.

    abstract：:The eleven-nineteen lysine-rich leukemia protein (ELL) is a key regulator of RNA polymerase II mediated transcription. ELL facilitates RNA polymerase II transcription pause site entry and release by dynamically interacting with p300 and the positive transcription elongation factor b (P-TEFb). In this study, we investi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.07.072

    authors： Fufa TD,Byun JS,Wakano C,Fernandez AG,Pise-Masison CA,Gardner K

    更新日期：2015-09-11 00:00:00

  • Inhibitory effect of porphyrins on the proliferation of mouse spleen lymphocytes in vitro.

    abstract：:The influence of various porphyrins (deuteroporphyrin IX, mesoporphyrin IX, protoporphyrin IX, hematoporphyrin) and two related compounds (hemin, biliverdin) on the spontaneous proliferation of mouse spleen lymphocytes has been estimated in vitro by the 3H-thymidine uptake assay. It has been found that porphyrins (end...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)90522-9

    authors： Stepien H,Kunert-Radek J,Stanisz A,Zerek-Melen G,Pawlikowski M

    更新日期：1991-01-15 00:00:00

  • Trehalose targets Nrf2 signal to alleviate d-galactose induced aging and improve behavioral ability.

    abstract：:As an important factor leading to aging and chronic diseases, oxidative stress has become a hot research topic. Trehalose is a natural sugar widely found in many edible plants, animals and natural microorganisms, and recent studies have suggested that trehalose is an antioxidant, although its underlying molecular mech...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.10.088

    authors： Sun L,Zhao Q,Xiao Y,Liu X,Li Y,Zhang J,Pan J,Zhang Z

    更新日期：2020-01-01 00:00:00

  • ATR microspectroscopy with multivariate analysis segregates grades of exfoliative cervical cytology.

    abstract：:Although cervical cancer screening in the UK has led to reductions in the incidence of invasive disease, this programme remains flawed. We set out to examine the potential of infrared (IR) microspectroscopy to allow the profiling of cellular biochemical constituents associated with disease progression. Attenuated tota...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.11.005

    authors： Walsh MJ,Singh MN,Pollock HM,Cooper LJ,German MJ,Stringfellow HF,Fullwood NJ,Paraskevaidis E,Martin-Hirsch PL,Martin FL

    更新日期：2007-01-05 00:00:00

  • Tissue distribution and subcellular localization of a variant form of the human ST2 gene product, ST2V.

    abstract：:The human ST2 gene has been known to encode three splice variants; namely, a soluble secreted form of ST2, a transmembrane form of ST2L, and ST2V of undetermined localization. Therefore, analysis of tissue distribution and subcellular localization of ST2V is important to elucidate functional relationships among the th...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.5306

    authors： Tago K,Noda T,Hayakawa M,Iwahana H,Yanagisawa K,Yashiro T,Tominaga S

    更新日期：2001-08-03 00:00:00

  • Suppressor of cytokine signaling 1 suppresses muscle differentiation through modulation of IGF-I receptor signal transduction.

    abstract：:Suppressor of cytokine signaling (SOCS) 1 was initially identified as an intracellular negative feedback regulator of the JAK-STAT signal pathway. Recently, it has been suggested that SOCS1 affects signals of growth factors and hormones. One of them, SOCS1, is also known to be involved in auto-regulation of IRS-1-medi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.01.046

    authors： Inaba M,Saito H,Fujimoto M,Sumitani S,Ohkawara T,Tanaka T,Kouhara H,Kasayama S,Kawase I,Kishimoto T,Naka T

    更新日期：2005-03-25 00:00:00

  • Development of membrane-potential responsiveness by myeloid leukemia cells during neutrophilic differentiation.

    abstract：:The ability of a myeloid leukemia cell line (HL-60) to undergo membrane electrical potential changes was followed during neutrophilic differentiation induced by 2 compounds. Membrane-potential changes were induced with 12-O-tetradecanoylphorbol 13-acetate (TPA) or formyl-methionyl-leucyl-phenylalanine (FMLP) and were ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(84)80224-7

    authors： Brown GE,Fischkoff SA,Ordonez JV

    更新日期：1984-09-28 00:00:00

  • Loss of alpha I type I collagen gene expression in rat clonal bone cell lines is accompanied by DNA methylation.

    abstract：:Four clonal cell lines subcloned from a clonal population of fetal rat calvaria cells show a loss of type I collagen synthesis. Northern blot analysis showed that the level of alpha 1(I) collagen mRNA expression in each of the clonal populations parallels the level of collagen protein expression in each of these cell ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)90836-x

    authors： Waye MM,Robinson R,Orfanides AG,Aubin JE

    更新日期：1989-08-15 00:00:00

  • Systemic identification of estrogen-regulated genes in breast cancer cells through cap analysis of gene expression mapping.

    abstract：:To explore the estrogen-regulated genes genome-widely in breast cancer, cap analysis of gene expression (CAGE) sequencing was performed in MCF-7 cells under estrogen treatment. Estrogen-regulated expressional changes were found in 1537 CAGE tag clusters (TCs) (⩾1.5 or ⩽0.66-folds). Among them, 15 TCs were situated in ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.04.033

    authors： Yamaga R,Ikeda K,Boele J,Horie-Inoue K,Takayama K,Urano T,Kaida K,Carninci P,Kawai J,Hayashizaki Y,Ouchi Y,de Hoon M,Inoue S

    更新日期：2014-05-09 00:00:00

  • In vitro polymerization of Mycobacterium leprae FtsZ OR Mycobacterium tuberculosis FtsZ is revived or abolished, respectively, by reciprocal mutation of a single residue.

    abstract：:A single residue that dramatically influences polymerization of principal cell division protein FtsZ of Mycobacterium leprae (MlFtsZ) and Mycobacterium tuberculosis (MtFtsZ) has been identified. Soluble, recombinant MlFtsZ did not show polymerization in vitro, in contrast to MtFtsZ, which polymerised. Mutation of the ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.01.115

    authors： Gupta P,Srinivasan R,Rajeswari H,Indi S,Ajitkumar P

    更新日期：2008-04-04 00:00:00

  • High definition profiling of autoantibodies to glutamic acid decarboxylases GAD65/GAD67 in stiff-person syndrome.

    abstract：:Highly reliable biomarkers for the diagnosis of neurological diseases are not widely available. Here we evaluated a luciferase immunoprecipitation technology (LIPS) for the diagnosis of a CNS autoimmune disorder, stiff-person syndrome (SPS). Analysis by LIPS of 40 sera samples from SPS and control subjects for anti-GA...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.11.077

    authors： Burbelo PD,Groot S,Dalakas MC,Iadarola MJ

    更新日期：2008-02-01 00:00:00

  • Identification of cyclic AMP response element in the human renin gene.

    abstract：:In order to identify the mechanism by which cyclic AMP stimulates expression of the human renin gene (REN), the effect of forskolin was tested in transient expression analyses of REN 5'-flanking DNA-chloramphenicol acetyltransferase (CAT) reporter gene constructs in secondary cultures of human chorio-decidual cells, a...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1994.1451

    authors： Smith DL,Morris BJ,Do YS,Law RE,Shaw KJ,Hseuh WA

    更新日期：1994-04-15 00:00:00

  • A metal-dependent form of protein phosphatase 2A.

    abstract：:Highly purified bovine heart protein phosphatase 2A catalytic subunit lost virtually all of its activity during storage at -70 degrees. When the enzyme was preincubated with Co2+, over 35% of the original activity was restored. Freshly prepared protein phosphatase 2A purified from bovine heart was stimulated at least ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1995.1334

    authors： Cai L,Chu Y,Wilson SE,Schlender KK

    更新日期：1995-03-08 00:00:00

  • Hypoxia promotes apoptosis of human neuroblastoma cell lines with enhanced N-myc expression.

    abstract：:We have examined the effect of hypoxia and nutrient depletion on the growth of human neuroblastoma cells with normal or enhanced expression of the N-myc oncogene. The combination of both conditions reduced the growth of neuroblastoma cells with normal N-myc expression. However, this effect was much more pronounced in ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.4342

    authors： Rössler J,Schwab M,Havers W,Schweigerer L

    更新日期：2001-02-23 00:00:00