Baculovirus cyclobutane pyrimidine dimer photolyases show a close relationship with lepidopteran host homologues.

Abstract:

:Cyclobutane pyrimidine dimer (CPD) photolyases repair ultraviolet (UV)-induced DNA damage using blue light. To get insight in the origin of baculovirus CPD photolyase (phr) genes, homologues in the lepidopteran insects Chrysodeixis chalcites, Spodoptera exigua and Trichoplusia ni were identified and characterized. Lepidopteran and baculovirus phr genes each form a monophyletic group, and together form a well-supported clade within the insect photolyases. This suggests that baculoviruses obtained their phr genes from an ancestral lepidopteran insect host. A likely evolutionary scenario is that a granulovirus, Spodoptera litura GV or a direct ancestor, obtained a phr gene. Subsequently, it was horizontally transferred from this granulovirus to several group II nucleopolyhedroviruses (NPVs), including those that infect noctuids of the Plusiinae subfamily.

journal_name

Insect Mol Biol

journal_title

Insect molecular biology

authors

Biernat MA,Ros VI,Vlak JM,van Oers MM

doi

10.1111/j.1365-2583.2011.01076.x

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

457-64

issue

4

eissn

0962-1075

issn

1365-2583

journal_volume

20

pub_type

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