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[Cardiovascular risk in Spanish smokers compared to non-smokers: RETRATOS study].

Abstract：

AIM:To evaluate the level of cardiovascular risk in smokers seenin Primary Care clinics. DESIGN:Epidemiologic, cross-sectional and multicentre study. SETTING:Primary Care. PATIENTS:Every investigator included 4 consecutive patients (3 smokers, 1 non-smoker) aged 35-50 years, who came to the clinic for any reason. A total of 2,184 patients were included; 2,124 (1,597 smokers; 527 non-smokers) were evaluated and 60 patients were excluded because they did not meet with selection criteria. MEASUREMENTS:The 10-year risk of suffering from a fatal cardiovascular disease (CVDR) was calculated according to the SCORE (Systematic Coronary Risk Evaluation) model. The 10-year lethal CVR according SCORE model, was classified as: very high (> 15%), high (10-14%), slightly high (5-9%), average (3-4%), low (2%), very low (1%) and negligible (< 1%). A logistical regression model was used to estimate the relationship between smoking and prior cardiovascular events. RESULTS:10-year fatal CVDR according to the SCORE model was significantly higher in smokers (40±5.3) vs. non-smokers (1.9±2.5) (P<.0001). RISK STRATIFICATION:low (< 3%) [78.0% non-smokers vs. 60.7% smokers (P<.0001)]; intermediate (3-5%) [11.1% non-smokers vs. 12.6% smokers (P<.001)]; high (> 5%) [10.9% non-smokers vs. 26.7% smokers (P<.001)]. The logistical regression model showed that non-smokers vs. smokers had less probability of suffering myocardial infarction (OR 0.3; 95% confidence interval (95% CI): 0.1-0.8; P<.0001), peripheral vascular disease (OR 0.6; 95% CI: 0.4-1.0; P=.0180) and chronic obstructive lung disease (OR 0.18; 95% CI: 0.1-0.2; P=.0507). CONCLUSIONS:Smoking is related to a high risk of fatal cardiovascular disease. Active promotion in Primary Care clinics of measures aimed at reducing the prevalence of the smoking habit would lead to a lowering of cardiovascular morbidity and mortality.

journal_name

Aten Primaria

journal_title

Atencion primaria

authors

Fernández de Bobadilla J,Sanz de Burgoa V,Garrido Morales P,López de Sá E,en representación de los investigadores del estudio RETRATOS.

doi

10.1016/j.aprim.2010.10.005

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

595-603

issue

eissn

0212-6567

issn

1578-1275

pii

S0212-6567(11)00066-7

journal_volume

pub_type

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[Cardiovascular risk in Spanish smokers compared to non-smokers: RETRATOS study].