Immunopathogenesis of severe asthma.

Abstract:

:Severe asthma is a complex heterogeneous disease with substantial unmet clinical need. Understanding the immunopathogenesis is likely to provide insights into potential novel therapies. To date researchers have focussed primarily at a single scale for example genome, cell or whole organ physiology. In this review we shall summarise the current knowledge of the immunopathogenesis of severe asthma integrated across multiple scales to provide the insights into the structure function relationships required to begin to unravel the complexity of severe asthma.

journal_name

Curr Pharm Des

authors

Brightling CE,Gupta S,Hollins F,Sutcliffe A,Amrani Y

doi

10.2174/138161211795429028

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

667-73

issue

7

eissn

1381-6128

issn

1873-4286

pii

BSP/CPD/E-Pub/000362

journal_volume

17

pub_type

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