Total thyroidectomy for the surgical treatment of multinodular goiter.


PURPOSE:The indications for surgical treatment of multinodular goiter (MNG) are pressure symptoms, suspicion of malignancy, and cosmetic concerns. We report our clinical experience of performing total thyroidectomy (TT) for MNG, focusing on outcome and complications, to evaluate its effectiveness. METHODS:The medical records of 154 patients who underwent TT for MNG between 2005 and 2007 were reviewed retrospectively. We examined the ratio of thyroid nodules to the thyroid gland, pathological fine-needle aspiration biopsy findings, and the ultrasonographic characteristics of the nodules, and recorded the early and late postoperative complications. RESULTS:The most frequent indications for surgery were large nodules with or without radiological suspicion of malignancy (65%), hyperthyroidism (20%), and cosmetic problems or compression symptoms (15%). Seventeen (11%) patients had symptomatic, transient hypocalcemia, and 1 (0.6%) had permanent hypocalcemia. Other complications included hematoma in 1 (0.6%) patient, temporary unilateral recurrent laryngeal nerve palsy in 10 (6.4%), permanent unilateral recurrent laryngeal nerve palsy in 3 (1.9%), and seroma in 2 (1.3%). There was no significant relationship between complications and histopathology, nodule size, thyroid size, hyperthyroidism, age, or gender. CONCLUSION:Total thyroidectomy is the right surgical decision for MNG since it achieves complete remission of symptoms and eliminates malignancy, with low morbidity and mortality rates.


Surg Today


Surgery today


Dogan L,Karaman N,Yilmaz KB,Ozaslan C,Atalay C




Has Abstract


2011-03-01 00:00:00












  • Immunohistochemical distribution of bombesin-positive pulmonary neuroendocrine cells in a congenital diaphragmatic hernia.

    abstract::Morphometrical analyses of the immunohistochemical expression of bombesin, which is one of the peptides produced by pulmonary neuroendocrine (PNE) cells, were carried out on the bronchioles of human congenital diaphragmatic hernia (CDH) neonates, and the findings were then compared with those in a gestational and post...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Asabe K,Tsuji K,Handa N,Kajiwara M,Suita S

    更新日期:1999-01-01 00:00:00

  • Chyluria after ligation of the thoracic duct: a rare complication after thoracoscopic-assisted esophagectomy for esophageal cancer.

    abstract::Chyluria is leakage of lymphatic fluid into the urine, following trauma to or obstruction of the lymphatic system. We herein report a rare case of chyluria after esophagectomy for esophageal cancer. A 69-year-old male complaining of epigastric pain and reflux symptoms was diagnosed with advanced esophageal cancer and ...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Takeno A,Tamura S,Miki H,Tanigawa N,Taniguchi H,Nakahira S,Suzuki R,Nakata K,Takeda Y,Kato T

    更新日期:2014-04-01 00:00:00

  • Laparoscopic splenectomy for a giant splenic epidermoid cyst: report of a case.

    abstract::The use of laparoscopic splenectomy has increased in recent years, primarily for patients with idiopathic thrombocytopenic purpura (ITP). We describe herein the first known case of a laparoscopic splenectomy to be performed in Japan for a patient with a giant splenic epidermoid cyst. A 26-year-old woman presented to o...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Sakamoto Y,Yunotani S,Edakuni G,Mori M,Iyama A,Miyazaki K

    更新日期:1999-01-01 00:00:00

  • A prognostic index for colorectal cancer based on preoperative absolute lymphocyte, monocyte, and neutrophil counts.

    abstract:PURPOSE:Associations between the preoperative absolute neutrophil count (NC), lymphocyte count (LC), and monocyte count (MC) in the peripheral blood and the prognosis of colorectal cancer (CRC) patients have not been widely studied. METHODS:We enrolled 361 patients who underwent surgery for CRC between January 2007 an...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Tanio A,Saito H,Uejima C,Takaya S,Yamamoto M,Tokuyasu N,Sakamoto T,Honjo S,Ashida K,Fujiwara Y

    更新日期:2019-03-01 00:00:00

  • Separate functions of alpha2beta1 and alpha3beta1 integrins in the metastatic process of human gastric carcinoma.

    abstract::The expression of alpha2beta1 and alpha3beta1 integrins was studied immunohistochemically in 110 resected human gastric carcinomas. Formalin-fixed and paraffin-embedded samples were serially sectioned and stained with monoclonal antibodies specifically against the alpha2 and alpha3 subunits of beta1 integrins. Approxi...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Ura H,Denno R,Hirata K,Yamaguchi K,Yasoshima T

    更新日期:1998-01-01 00:00:00

  • Splenic arterial hemorrhage in pancreatitis: report of three cases.

    abstract::Gastrointestinal hemorrhage is a rare complication of pancreatitis and can involve any of the peripancreatic vessels. The three cases reported herein illustrate the involvement of the splenic artery in diverse forms of pancreatitis: chronic pancreatitis, a pancreatic pseudocyst, and necrotizing pancreatitis. Bleeding ...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Singh G,Lobo DR,Jindal A,Marwaha RK,Khanna SK

    更新日期:1994-01-01 00:00:00

  • Results and complications after laparoscopic sleeve gastrectomy.

    abstract:PURPOSE:Laparoscopic sleeve gastrectomy (SG) has gained popularity and acceptance among bariatric surgeons, mainly due its low morbidity and mortality. The purpose of the present study was to evaluate the efficacy of SG on weight loss, and to determine the postoperative course, clinical presentation and treatment of co...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Mittermair R,Sucher R,Perathoner A

    更新日期:2014-07-01 00:00:00

  • Preventive effect of a traditional herbal medicine, Hochu-ekki-to, on immunosuppression induced by surgical stress.

    abstract:PURPOSE:To examine the effect of preoperative administering of a Japanese traditional herbal medicine, Hochu-ekki-to (TJ-41), on immunosuppression induced by surgical stress in patients with gastrointestinal malignancies. METHODS:To monitor the immune functions, the mitochondrial membrane potential (MMP) and natural k...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Kimura M,Sasada T,Kanai M,Kawai Y,Yoshida Y,Hayashi E,Iwata S,Takabayashi A

    更新日期:2008-01-01 00:00:00

  • Metastatic mode and DNA ploidy in gastric carcinoma.

    abstract::We studied the amounts of nuclear DNA in gastric cancer metastases histologically and cytochemically by flow cytometry, which was performed retrospectively on paraffin-embedded specimens from 95 patients. At surgery, all cases of aneuploid cancer were positive for lymph node metastases. Liver metastases were frequentl...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Umehara Y,Kimura T,Yoshida M,Oba N,Harada Y

    更新日期:1992-01-01 00:00:00

  • Inhibition of acute rejection after skin or cardiac transplantation by administration of donor antigens in the rat.

    abstract:PURPOSE:We examined differences in host immunologic changes induced by the intravenous or intraportal administration of donor antigens at engrafting and evaluated their contribution to graft survival using a rat transplantation model. METHODS:Lewis rat recipients were given either an intravenous or intraportal injecti...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Shirouzu Y,Hikida S,Tanigawa H,Shirouzu K

    更新日期:2004-01-01 00:00:00

  • Intrahepatic cholangiocarcinoma with lymph node metastasis successfully treated by immunotherapy with CD3-activated T cells and dendritic cells after surgery: report of a case.

    abstract::Intrahepatic cholangiocarcinoma (ICC) with lymph node (LN) metastasis is generally associated with a poor prognosis. However, we treated ICC with LN metastasis successfully by surgery and postoperative immunotherapy in a 59-year-old woman. The immunotherapy consisted of CD3-activated T cells and tumor lysate- or pepti...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Higuchi R,Yamamoto M,Hatori T,Shimizu K,Imai K,Takasaki K

    更新日期:2006-01-01 00:00:00

  • Is the cleft lift procedure for non-acute sacrococcygeal pilonidal disease a definitive treatment? Long-term outcomes in 74 patients.

    abstract:PURPOSE:No definitive surgical treatment for non-acute pilonidal disease has been established thus far. We herein report the short-term and long-term outcomes of 74 consecutive patients who underwent the cleft lift procedure for non-acute pilonidal disease. METHODS:A total of 74 consecutive patients who underwent the ...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Ortega PM,Baixauli J,Arredondo J,Bellver M,Sánchez-Justicia C,Ocaña S,Hernández-Lizoain JL

    更新日期:2014-12-01 00:00:00

  • Preoperative endoscopic tattooing using India ink to determine the resection margins during totally laparoscopic distal gastrectomy for gastric cancer.

    abstract:PURPOSE:This study was conducted to determine whether establishing the proximal resection line using India ink tattooing can ensure safe resection margins during totally laparoscopic distal gastrectomy. METHODS:This retrospective study included 81 patients who underwent totally laparoscopic distal gastrectomy for gast...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Yamazaki Y,Kanaji S,Takiguchi G,Urakawa N,Hasegawa H,Yamamoto M,Matsuda Y,Yamashita K,Matsuda T,Oshikiri T,Nakamura T,Suzuki S,Kakeji Y

    更新日期:2021-01-01 00:00:00

  • Awake thoracic surgery versus chemical pleurodesis for intractable secondary spontaneous pneumothorax.

    abstract:PURPOSE:To compare the outcomes and efficacy of awake video-assisted thoracic surgery (VATS) with those of chemical pleurodesis for intractable secondary spontaneous pneumothorax (SSP). METHODS:We analyzed, retrospectively, 60 consecutive patients who underwent awake VATS (n = 22) or chemical pleurodesis (n = 38) for ...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Noda M,Watanabe T,Matsuda Y,Sakurada A,Hoshikawa Y,Okada Y

    更新日期:2016-11-01 00:00:00

  • Giant hemorrhagic adrenal pseudocyst in a primiparous pregnancy: report of a case.

    abstract::Adrenal cysts are rare and are usually discovered incidentally during diagnostic imaging, surgery, or autopsy. Most cystic lesions of the adrenal gland are nonfunctioning and become symptomatic when complicated by rupture, hemorrhage, or infection. A 40-year-old woman presented with a history of gradual-onset pain in ...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Karaman K,Teke Z,Dalgic T,Ulas M,Seven MC,Zulfikaroglu E,Sakaogullari Z,Bostanci EB

    更新日期:2011-01-01 00:00:00

  • Significance of prophylactic modified radical neck dissection for patients with low-risk papillary thyroid carcinoma measuring 1.1-3.0 cm: first report of a trial at Kuma Hospital.

    abstract:PURPOSE:Papillary thyroid carcinoma (PTC) frequently metastasizes to and recurs in regional lymph nodes. Of the two compartments, the central compartment can be dissected through the same wound as the thyroidectomy, and the central node dissection (CND) is routinely performed in most Japanese surgical departments. Howe...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Ito Y,Tsushima Y,Masuoka H,Yabuta T,Fukushima M,Inoue H,Tomoda C,Kihara M,Higashiyama T,Takamura Y,Kobayashi K,Miya A,Miyauchi A

    更新日期:2011-11-01 00:00:00

  • Comparison of the risk of surgical site infection and feasibility of surgery between sennoside versus polyethylene glycol as a mechanical bowel preparation of elective colon cancer surgery: a randomized controlled trial.

    abstract:PURPOSE:To validate the usefulness of sennoside as a substitute for polyethylene glycol (PEG) as a mechanical bowel preparation (MBP) for elective colon cancer surgery. METHODS:We performed a prospective randomized non-inferiority trial comparing the use of sennoside and PEG in MBP for elective colon cancer surgery, i...

    journal_title:Surgery today

    pub_type: 杂志文章,随机对照试验


    authors: Tajima Y,Ishida H,Yamamoto A,Chika N,Onozawa H,Matsuzawa T,Kumamoto K,Ishibashi K,Mochiki E

    更新日期:2016-06-01 00:00:00

  • Bilateral recurrent pneumothorax complicating chemotherapy for pulmonary metastatic breast ductal carcinoma: report of a case.

    abstract::Secondary spontaneous pneumothorax (SSP) is a rare complication of chemotherapy for pulmonary metastases and to the best of our knowledge, only 28 cases have been described, most of which occurred in patients with osteosarcoma or germ cell tumors. We present herein the case of a 56-year-old woman in whom bilateral and...

    journal_title:Surgery today

    pub_type: 杂志文章,评审


    authors: Bini A,Zompatori M,Ansaloni L,Grazia M,Stella F,Bazzocchi R

    更新日期:2000-01-01 00:00:00

  • Changes in the choice of thyroidectomy for benign thyroid disease.

    abstract:PURPOSES:There is an increasing trend towards performing more radical resections instead of a subtotal resection for benign thyroid disease. The aim of this study was to examine the effect of this change in practice on the surgical treatment of bilateral thyroid diseases in this unit. METHODS:The data on 367 patients ...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Citgez B,Uludag M,Yetkin G,Yener F,Akgun I,Isgor A

    更新日期:2013-06-01 00:00:00

  • Clinical results of endovenous LASER ablation (EVLA) using low linear endovenous energy density (LEED) combined with high ligation for great saphenous varicose veins.

    abstract:PURPOSE:This study was designed to analyze the efficacy and complications in endovenous LASER ablation (EVLA) with 1470 nm diode lasers using low linear endovenous energy density (LEED) combined with high ligation for varicose veins of the great saphenous vein (GSV). METHODS:One hundred and sixteen limbs of 102 patien...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Park YS,Kim YW,Park YJ,Kim DI

    更新日期:2016-09-01 00:00:00

  • Peripheral edema after esophagectomy.

    abstract::Patients who have undergone major surgery such as esophagectomy may develop peripheral edema in the immediate postoperative period, the cause of which is not fully understood. The purpose of this study was therefore to determine the mechanism of this phenomenon. Finger edema was measured as a marker for peripheral ede...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Minamiya Y,Kitamura M,Saito R,Saito H,Matsumoto H,Abo S

    更新日期:1998-01-01 00:00:00

  • Current status of conversion surgery for stage IV gastric cancer.

    abstract::Palliative chemotherapy with best supportive care is a mainstay for patients with gastric cancer (GC) and distant metastasis. However, with advances in GC chemotherapy, multimodal treatment, including perioperative chemotherapy plus conversion surgery, has attracted attention as a new strategy to improve the outcome o...

    journal_title:Surgery today

    pub_type: 杂志文章,评审


    authors: Kinoshita J,Yamaguchi T,Moriyama H,Fushida S

    更新日期:2021-01-23 00:00:00

  • Postoperative outcome of insufficient surgery for small differentiated thyroid carcinoma.

    abstract::We performed conservative surgery for small differentiated thyroid carcinoma, but also inadvertently carried out minimal insufficient surgery, such as enucleation (Ex) or partial lobectomy (pLx) without regional node dissection for malignant thyroid nodules. In this study, the long-term postoperative outcome after suc...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Shingu K,Sugenoya A,Kobayashi S,Kasuga Y,Fujimori M,Asanuma K,Hama Y,Ito K,Maruyama M,Itoh N,Amano J

    更新日期:1997-01-01 00:00:00

  • Surgery or stereotactic body radiotherapy for elderly stage I lung cancer? A propensity score matching analysis.

    abstract:PURPOSE:The aim of this study was to compare the outcomes of surgery and stereotactic body radiotherapy (SBRT) for elderly clinical stage I non-small cell lung cancer (NSCLC) patients. METHODS:Patients ≥80 years of age with clinical stage I NSCLC between August 2008 and December 2014 were treated either surgery or SBR...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Miyazaki T,Yamazaki T,Nakamura D,Sato S,Yamasaki N,Tsuchiya T,Matsumoto K,Kamohara R,Hatachi G,Nagayasu T

    更新日期:2017-12-01 00:00:00

  • Phase II study of weekly paclitaxel by one-hour infusion for advanced gastric cancer.

    abstract:PURPOSE:A phase clinical II trial was conducted to determine the antitumor activity and toxicity of weekly paclitaxel administered to patients with advanced gastric cancer. METHODS:Sixty-eight patients with advanced gastric cancer and performance status 0-2 were treated with 80 mg/m2 paclitaxel over 1 h following a sh...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Emi Y,Yamamoto M,Takahashi I,Orita H,Kakeji Y,Kohnoe S,Maehara Y

    更新日期:2008-01-01 00:00:00

  • Primary gastric T-cell lymphoma without human T-lymphotropic virus type 1: report of a case.

    abstract::Although primary gastric malignant lymphoma accounts for slightly more than 10% of all lymphomas at extranodular sites, it is relatively rare clinically, representing only 1% of all malignant diseases of the stomach. In addition, most such diseases tend to be B-cell lymphoma, while T-cell lymphoma is extremely rare. W...

    journal_title:Surgery today

    pub_type: 杂志文章,评审


    authors: Watanabe M,Moriyama Y

    更新日期:2002-01-01 00:00:00

  • The impact of frailty syndrome and risk scores on emergency cholecystectomy patients.

    abstract:PURPOSE:Cholecystectomy, which is one of the most common surgical procedures, is also performed in the emergency setting. A number of risk scores have been introduced in recent studies; moreover, over the last few years literature has focused on surgical patients with frailty syndrome. The aim of the present study is t...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Lorenzon L,Costa G,Massa G,Frezza B,Stella F,Balducci G

    更新日期:2017-01-01 00:00:00

  • Colonic tattooing using fluorescence imaging with light-emitting diode-activated indocyanine green: a feasibility study.

    abstract:PURPOSE:We investigated the feasibility of a fluorescence imaging technique using light-emitting diode (LED)-activated indocyanine green (ICG) fluorescence. METHODS:Indocyanine green injections were given to patients undergoing preoperative colonoscopy for early colon cancer or colon adenoma. During subsequent laparot...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Watanabe M,Tsunoda A,Narita K,Kusano M,Miwa M

    更新日期:2009-01-01 00:00:00

  • Impact of Surgical Infection Society/Infectious Disease Society of America-recommended antibiotics on postoperative intra-abdominal abscess with image-guided percutaneous abscess drainage following gastrointestinal surgery.

    abstract:PURPOSE:The aims of this study were to reveal how using the antibiotics recommended by the 2010 Surgical Infection Society (SIS) and Infectious Disease Society of America (IDSA) guidelines can affect the therapeutic outcomes. METHODS:We reviewed the cases of 53 patients with a postoperative intra-abdominal abscess wit...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Okita Y,Kobayashi M,Araki T,Fujikawa H,Koike Y,Otake K,Mikihiro I,Toiyama Y,Ohi M,Tanaka K,Inoue Y,Uchida K,Mohri Y,Yamakado K,Kusunoki M

    更新日期:2015-08-01 00:00:00

  • Regulation of methionine adenosyltransferase activity by the glutathione level in rat liver during ischemia-reperfusion.

    abstract::Hepatic ischemia was induced by clamping the hepatic artery, portal vein, and bile duct. After 15 min of ischemia, the hepatic glutathione (GSH) content rapidly decreased. On the other hand, after the start of reperfusion, the hepatic GSH levels promptly increased and reached a peak at about 1 h, and thereafter decrea...

    journal_title:Surgery today

    pub_type: 杂志文章


    authors: Ito K,Miwa N,Hagiwara K,Yano T,Shimizu-Saito K,Goseki N,Iwai T,Horikawa S

    更新日期:1999-01-01 00:00:00