Abstract:
:We propose a rate process model for describing photochemical damage to retinal cells by short wavelength laser exposures. The rate equation for photochemical damage contains a positive rate that is temperature independent, and a negative (quenching) rate that is temperature dependent. Using the traditional Arrhenius integral to describe thermal damage, we derive damage threshold doses for both thermal and photochemical mechanisms, and show that the model accounts for the sharp transition from thermal to photochemical damage thresholds that have recently been observed in an in-vitro retinal model.
journal_name
J Biomed Optjournal_title
Journal of biomedical opticsauthors
Clark CD 3rd,Denton ML,Thomas RJdoi
10.1117/1.3544504subject
Has Abstractpub_date
2011-02-01 00:00:00pages
020504issue
2eissn
1083-3668issn
1560-2281journal_volume
16pub_type
信件abstract::Vectorial models of focused beams are important to a variety of fields including microscopy, lithography, optical physics, and biomedical imaging. This has led to many models being developed, which calculate how beams of various profiles are focused both in free space and in the presence of stratified media. The major...
journal_title:Journal of biomedical optics
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abstract::Alzheimer's disease (AD) is a neurodegenerative disorder that leads to a decline in cognitive and intellectual abilities and an irreversible mental deterioration. Based on multidisciplinary AD research, the most universally accepted hypotheses on AD pathogenesis are the intracerebral aggregate formation of beta-amyloi...
journal_title:Journal of biomedical optics
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abstract::A transgenic mouse model with a Clim [co-factor of LIM (a combination of first letters of Lin-11 (C. elegans), ISL1 (rat), and Mec-3 (C. elegans) gene names) domain proteins] gene partially blocked in the epithelial compartment of its tissues is used to establish the sensitivity of intrinsic reflectance nonlinear opti...
journal_title:Journal of biomedical optics
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journal_title:Journal of biomedical optics
pub_type: 杂志文章
doi:10.1117/1.JBO.19.8.086004
更新日期:2014-08-01 00:00:00
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更新日期:2012-05-01 00:00:00
abstract::This paper presents a fiber Bragg grating (FBG)-instrumented prosthetic silicone liner that provides cushioning for the residual limb and can successfully measure interface pressures inside prosthetic sockets of lower-limb amputees in a simple and practical means of sensing. The liner is made of two silicone layers be...
journal_title:Journal of biomedical optics
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更新日期:2017-08-01 00:00:00
abstract::Fluorescence spectroscopy has been widely investigated as a technique for identifying pathological tissue; however, unrelated subject-to-subject variations in spectra complicate data analysis and interpretation. We describe and evaluate a new biosensing technique, differential laser-induced perturbation spectroscopy (...
journal_title:Journal of biomedical optics
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journal_title:Journal of biomedical optics
pub_type: 杂志文章
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更新日期:2013-07-01 00:00:00
abstract::Photodynamic therapy (PDT) is an alternative to radical surgical resection for T1a or nonresectable carcinomas of the gastroesophageal junction. Besides the concentration of the photosensitizer, the light distribution in tissue is responsible for tumor destruction. For this reason, knowledge about the behavior of ligh...
journal_title:Journal of biomedical optics
pub_type: 杂志文章
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journal_title:Journal of biomedical optics
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更新日期:2015-05-01 00:00:00
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journal_title:Journal of biomedical optics
pub_type: 信件
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abstract:UNLABELLED:Temperature changes caused by laser irradiation can promote damage to the surrounding dental tissues. In this study, we evaluated the temperature changes of recently extracted human mandibular incisors during intracanal irradiation with an 810-nm diode laser at different settings. Fifty mandibular incisors w...
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更新日期:2012-01-01 00:00:00
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journal_title:Journal of biomedical optics
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更新日期:2011-03-01 00:00:00
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journal_title:Journal of biomedical optics
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更新日期:2020-12-01 00:00:00
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journal_title:Journal of biomedical optics
pub_type: 杂志文章
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更新日期:2014-02-01 00:00:00
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journal_title:Journal of biomedical optics
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更新日期:2015-01-01 00:00:00
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journal_title:Journal of biomedical optics
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更新日期:2007-01-01 00:00:00
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journal_title:Journal of biomedical optics
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更新日期:2017-12-01 00:00:00
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journal_title:Journal of biomedical optics
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journal_title:Journal of biomedical optics
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更新日期:2013-06-01 00:00:00
abstract::Optical coherence tomography (OCT) is an emergent imaging tool used for noninvasive diagnosis of skin diseases. The present meta-analysis was carried out to assess the accuracy of OCT for the diagnosis of skin cancer. We conducted a systematic literature search though EMBASE, Medline, PubMed, the Cochrane Library, and...
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pub_type: 杂志文章,meta分析
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abstract::Ambulatory diffuse optical tomography (aDOT) is based on near-infrared spectroscopy (NIRS) and enables three-dimensional imaging of regional hemodynamics and oxygen consumption during a person’s normal activities. Although NIRS has been previously used for muscle assessment, it has been notably limited in terms of the...
journal_title:Journal of biomedical optics
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更新日期:2016-09-01 00:00:00
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journal_title:Journal of biomedical optics
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journal_title:Journal of biomedical optics
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更新日期:2013-11-01 00:00:00
abstract::Multiphoton microscopy has evolved into a powerful bioimaging tool in three dimensions. However, the ability to image biological specimens in-depth can be hindered by sample spherical aberration and scattering. These two phenomena can result in the degradation of image resolution and the loss of detected multiphoton s...
journal_title:Journal of biomedical optics
pub_type: 杂志文章
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abstract::Fourier transform infrared (FTIR) microspectroscopy has been used to estimate the spatial proteoglycan (PG) and collagen contents in articular cartilage (AC). However, it is not clear whether the results of FTIR analyses are consistent between different species. Our aim was to clarify how three different FTIR PG param...
journal_title:Journal of biomedical optics
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