High definition colonoscopy vs. standard video endoscopy for the detection of colonic polyps: a meta-analysis.


BACKGROUND AND STUDY AIMS:High definition colonoscopy may improve adenoma detection rates but studies report conflicting results. The aim of this meta-analysis was to compare the diagnostic yield of colonic polyps between high definition colonoscopy and standard video endoscopy (SVE). METHODS:Various electronic databases were searched for articles reporting on high definition colonoscopy. The pooled incremental yield and pooled weighted mean difference of high definition colonoscopy over SVE for polyp detection was determined. RESULTS:Five studies involving 4422 patients provided data on the total number of polyps detected. The incremental yield of high definition colonoscopy for the detection of any polyp was 3.8 % (95 % confidence interval [CI] 1 % - 6.7 %) with a number needed to treat (NNT) of 26. For the detection of adenomatous polyps the incremental yield was 3.5 % (95 %CI 0.9 % - 6.1 %) with an NNT of 28. There were no differences between high definition and SVE in the detection of high risk adenomas, with an incremental yield of -0.1 % (95 %CI -1.7 % to 1.6 %). When grouped according to the overall adenoma detection rate of the studies (> 50 % or < 50 %) the pooled weighted mean difference in small adenoma detection was better with high definition colonoscopy ( P = 0.035). CONCLUSIONS:There were marginal differences between high definition colonoscopy and SVE for the detection of colonic polyps/adenomas. High definition colonoscopy did not improve the detection of high risk adenomas. Due to differences in the adenoma detection rate between the studies and the nonrandomized study design of three of the five studies, these results need to be interpreted with caution. Prospective randomized trials looking at long term outcomes such as rates of interval or missed cancers are needed to clarify the clinical implications.






Subramanian V,Mannath J,Hawkey CJ,Ragunath K




Has Abstract


2011-06-01 00:00:00












  • Contrast-harmonic endoscopic ultrasound for the diagnosis of pancreatic adenocarcinoma: a prospective multicenter trial.

    abstract:BACKGROUND AND STUDY AIMS:Histology is the gold standard for the diagnosis of pancreatic adenocarcinoma. However, the negative predictive value of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for the diagnosis remains low. The aims of this prospective multicenter study were: (1) to compare the performa...


    pub_type: 杂志文章,多中心研究


    authors: Gincul R,Palazzo M,Pujol B,Tubach F,Palazzo L,Lefort C,Fumex F,Lombard A,Ribeiro D,Fabre M,Hervieu V,Labadie M,Ponchon T,Napoléon B

    更新日期:2014-05-01 00:00:00

  • Idiopathic esophageal varices with longitudinal erosion.

    abstract::A 60-year-old man with idiopathic esophageal varices is presented. Endoscopy and endoscopic ultrasonography clearly demonstrated a longitudinal erosion on one of two straight varices. There was no evidence of portal hypertension, and no abnormality in the superior vena cava system. Peritoneoscopy and liver biopsy were...


    pub_type: 杂志文章


    authors: Motoo Y,Okai T,Ohta H,Matsui O,Sawabu N

    更新日期:1989-11-01 00:00:00

  • Propofol versus midazolam for conscious sedation guided by processed EEG during endoscopic retrograde cholangiopancreatography: a prospective, randomized, double-blind study.

    abstract:BACKGROUND AND STUDY AIMS:Endoscopic retrograde cholangiopancreatography (ERCP) is a complex procedure, which requires appropriate sedation. The aim of this prospective, randomized, double-blind study was to compare the quality and characteristics of sedation with midazolam or propofol in patients undergoing ERCP. PAT...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Krugliak P,Ziff B,Rusabrov Y,Rosenthal A,Fich A,Gurman GM

    更新日期:2000-09-01 00:00:00

  • Data quality of the German screening colonoscopy registry.

    abstract:BACKGROUND AND STUDY AIMS:The German screening colonoscopy program is accompanied by a central registry that records the main outcome quality indicators, namely colonoscopy completion rate, adenoma detection rate (ADR), and complication rate. The aim of the present study was to assess the quality of these registry data...


    pub_type: 杂志文章


    authors: Adler A,Lieberman D,Aminalai A,Aschenbeck J,Drossel R,Mayr M,Mroß M,Scheel M,Schröder A,Keining C,Stange G,Wiedenmann B,Gauger U,Altenhofen L,Rösch T

    更新日期:2013-10-01 00:00:00

  • Premedication for upper gastrointestinal endoscopy: a comparative study of flunitrazepam, diazepam and neuroleptanalgesia.

    abstract::Flunitrazepam or diazepam with atropine and a combination of phenoperidine, droperidol and cyclizine (neuroleptanalgesia) were compared as premedication in three groups of 25 patients undergoing routine upper gastrointestinal endoscopy. Drug doses were titrated carefully against response and all three regimes were fou...


    pub_type: 杂志文章


    authors: Nimmo WS,Forrest JA,Heading RC,Finlayson ND,Prescott LF

    更新日期:1978-08-01 00:00:00

  • The use of endoscopic ultrasonography in the diagnosis and staging of carcinoma of the papilla of Vater.

    abstract::Endoscopic ultrasonography (EUS) was evaluated in the diagnosis of carcinoma of the papilla of Vater. Thirteen cases of carcinoma of the papilla examined by EUS were investigated with the aim of assessing the detection capability of EUS in comparison with other diagnostic tools, and its usefulness in diagnosing the ex...


    pub_type: 杂志文章


    authors: Yasuda K,Mukai H,Cho E,Nakajima M,Kawai K

    更新日期:1988-08-01 00:00:00

  • Massive rectal bleeding following transrectal ultrasound-guided prostate biopsy.

    abstract:BACKGROUND AND STUDY AIMS:Rectal bleeding is frequently seen in patients undergoing transrectal ultrasound (TRUS)-guided prostate biopsy, but is usually mild and stops spontaneously. We report five cases of life-threatening hemorrhage following this procedure, which were treated successfully by endoscopic injection. P...


    pub_type: 杂志文章,评审


    authors: Brullet E,Guevara MC,Campo R,Falcó J,Puig J,Prera A,Prats J,Del Rosario J

    更新日期:2000-10-01 00:00:00

  • In vitro evaluation of the radial and axial force of self-expanding esophageal stents.

    abstract:BACKGROUND AND STUDY AIMS:Technological innovation in esophageal stent design has progressed over the past decades, but the association between the mechanical properties of stent design and clinical outcome is still poorly understood. In this study the radial force and axial force of currently available stent designs w...


    pub_type: 杂志文章


    authors: Hirdes MM,Vleggaar FP,de Beule M,Siersema PD

    更新日期:2013-12-01 00:00:00

  • Endoscopic placement of expandable metal stents for biliary strictures--a preliminary report on experience with 33 patients.

    abstract::The main problem with palliative treatment of extrahepatic cholestasis with an endoscopic biliary endoprosthesis is clogging. One of the factors thought to be of importance is the diameter of the stent. In order to avoid being limited by the size of the instrumentation channel of the endoscope, expandable stents have ...


    pub_type: 杂志文章


    authors: Huibregtse K,Cheng J,Coene PP,Fockens P,Tytgat GN

    更新日期:1989-11-01 00:00:00

  • Buckling of redundant expansile stent distal to an oesophageal cancer: endoscopic management.

    abstract::This report describes a complication that occurred as a result of deploying an Ultraflex stent too low in relation to a stenosing carcinoma of the gastro-oesophageal junction. Intermittent kinking of the redundant lower end of the stent caused frequent episodes of total dysphagia. A percutaneous endoscopic gastrostomy...


    pub_type: 杂志文章


    authors: Sen S,Balaratnam N,Wood LA,Allison MC

    更新日期:1998-05-01 00:00:00

  • Endoscopy and antiplatelet agents. European Society of Gastrointestinal Endoscopy (ESGE) Guideline.

    abstract::With the increasing use of antiplatelet agents (APA), their management during the periendoscopic period has become a more common and more difficult problem. The increase in use is due to the availability of new drugs and the widespread use of drug-eluting coronary stents. Acute coronary syndromes can occur when APA th...


    pub_type: 杂志文章,实务指引


    authors: Boustière C,Veitch A,Vanbiervliet G,Bulois P,Deprez P,Laquiere A,Laugier R,Lesur G,Mosler P,Nalet B,Napoleon B,Rembacken B,Ajzenberg N,Collet JP,Baron T,Dumonceau JM,European Society of Gastrointestinal Endoscopy.

    更新日期:2011-05-01 00:00:00

  • European Society of Gastrointestinal Endoscopy (ESGE) Guideline Development Policy.

    abstract::Numerous scientific publications explore the field of gastrointestinal (GI) endoscopy (a Pubmed search currently yields > 73000 results). Therefore, guidelines have become an indispensable tool for incorporating up-to-date knowledge into daily clinical care. Since the 1990 s, the issuing of guidelines has been a centr...


    pub_type: 杂志文章


    authors: Dumonceau JM,Hassan C,Riphaus A,Ponchon T

    更新日期:2012-06-01 00:00:00

  • Current sedation and monitoring practice for colonoscopy: an International Observational Study (EPAGE).

    abstract:BACKGROUND AND STUDY AIMS:Sedation and monitoring practice during colonoscopy varies between centers and over time. Knowledge of current practice is needed to ensure quality of care and help focus future research. The objective of this study was to examine sedation and monitoring practice in endoscopy centers internati...


    pub_type: 杂志文章,多中心研究


    authors: Froehlich F,Harris JK,Wietlisbach V,Burnand B,Vader JP,Gonvers JJ,EPAGE Study Group.

    更新日期:2006-05-01 00:00:00

  • Preliminary experience using laparoscopic transcystic cholangioscopy for treatment of common bile duct stones.

    abstract::Laparoscopic transcystic cholangioscopy (LTC) in combination with electrohydraulic lithotripsy may be an alternative treatment to ERCP and sphincterotomy in patients with both gallbladder and common bile duct stones undergoing laparoscopic cholecystectomy. Preliminary experience using LTC lithotripsy in 13 cases is re...


    pub_type: 杂志文章


    authors: Ido K,Kimura K,Kawamoto C,Satoh S,Isoda N,Taniguchi Y,Suzuki T,Ohtani M,Kumagai M,Horikawa S

    更新日期:1992-11-01 00:00:00

  • The effect of endoscopic hemostasis with alcohol on the mortality rate of nonvariceal upper gastrointestinal hemorrhage. A randomized prospective study.

    abstract::One hundred and forty-five patients with nonvariceal upper GI hemorrhage, active or with stigmata (Forrest I and II) were divided into two groups according to the day of the week on which emergency endoscopy was performed: group A (78 patients) in which conventional treatment was applied (blood transfusions, antacids,...


    pub_type: 临床试验,杂志文章


    authors: Pascu O,Dräghici A,Acalovchi I

    更新日期:1989-03-01 00:00:00

  • Artificial intelligence for polyp detection during colonoscopy: a systematic review and meta-analysis.

    abstract:BACKGROUND: Artificial intelligence (AI)-based polyp detection systems are used during colonoscopy with the aim of increasing lesion detection and improving colonoscopy quality. PATIENTS AND METHODS: We performed a systematic review and meta-analysis of prospective trials to determine the value of AI-based polyp detec...


    pub_type: 杂志文章


    authors: Barua I,Vinsard DG,Jodal HC,Løberg M,Kalager M,Holme Ø,Misawa M,Bretthauer M,Mori Y

    更新日期:2020-06-17 00:00:00

  • Diminutive colonic polyps--clinical significance and management.

    abstract::Of 300 diminutive polyps (up to 5 mm) found at colonoscopy, 114 were neoplastic (37 per cent) and thus possible precursors of carcinoma. This suggests that all colonic polyps, regardless of size, should if possible be extirpated or coagulated. As polyps of this small size often escape detection roentgenologically, esp...


    pub_type: 杂志文章


    authors: Granqvist S,Gabrielsson N,Sundelin P

    更新日期:1979-02-01 00:00:00

  • Endoscopic submucosal dissection of early colorectal tumors using a grasping-type scissors forceps: a preliminary clinical study.

    abstract::To reduce the risk of complications related to endoscopic submucosal dissection (ESD), we developed a new grasping-type scissors forceps (GSF), which can grasp and incise the targeted tissue using an electrosurgical current. We prospectively evaluated the efficacy and safety of ESD using GSF for the removal of colorec...


    pub_type: 杂志文章


    authors: Akahoshi K,Okamoto R,Akahane H,Motomura Y,Kubokawa M,Osoegawa T,Nakama N,Chaen T,Oya M,Nakamura K

    更新日期:2010-05-01 00:00:00

  • Endoscopic removal of an embedded biliary Wallstent by piecemeal extraction.

    abstract::Expandable metal biliary stents are reserved for patients with unresectable malignant biliary obstruction. Occasionally, these stents may cause complications necessitating removal. We describe successful endoscopic removal of a biliary Wallstent one year after insertion in a patient who initially underwent placement o...


    pub_type: 杂志文章


    authors: Egan LJ,Baron TH

    更新日期:2000-06-01 00:00:00

  • Didactic training vs. computer-based self-learning in the prediction of diminutive colon polyp histology by trainees: a randomized controlled study.

    abstract::Background and study aim Experts can accurately predict diminutive polyp histology, but the ideal method to train nonexperts is not known. The aim of the study was to compare accuracy in diminutive polyp histology characterization using narrow-band imaging (NBI) between participants undergoing classroom didactic train...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Khan T,Cinnor B,Gupta N,Hosford L,Bansal A,Olyaee MS,Wani S,Rastogi A

    更新日期:2017-12-01 00:00:00

  • Fine-needle aspiration cytology guided by endoscopic ultrasonography: results in 141 patients.

    abstract:BACKGROUND AND STUDY AIMS:Diagnosis of submucosal lesions, pancreatic tumors, and mediastinal or celiac lymph nodes or masses is possible using endoscopic ultrasonography (EUS), but histological confirmation to differentiate between benign and malignant lesions is still required. The aim of this study was to evaluate t...


    pub_type: 杂志文章


    authors: Giovannini M,Seitz JF,Monges G,Perrier H,Rabbia I

    更新日期:1995-02-01 00:00:00

  • Chromoendoscopy using indigo carmine dye spraying with magnifying observation is the most reliable method for differential diagnosis between non-neoplastic and neoplastic colorectal lesions: a prospective study.

    abstract:BACKGROUND AND AIMS:Differential diagnosis between non-neoplastic and neoplastic lesions is very important at colonoscopy, since removal or biopsy of non-neoplastic polyps wastes time and resources. We therefore conducted a prospective study to examine whether indigo carmine dye spraying with and without magnification ...


    pub_type: 临床试验,杂志文章


    authors: Fu KI,Sano Y,Kato S,Fujii T,Nagashima F,Yoshino T,Okuno T,Yoshida S,Fujimori T

    更新日期:2004-12-01 00:00:00

  • Impact of trainee involvement on the outcome of ERCP procedures: results of a prospective multicenter observational trial.

    abstract:BACKGROUND:Training in advanced endoscopic techniques such as endoscopic retrograde cholangiopancreatography (ERCP) should be driven by key performance measures and standardized competence assessment in order to provide safe and high-quality interventions. We aimed to determine whether the involvement of trainees influ...


    pub_type: 杂志文章


    authors: Voiosu T,Boskoski I,Voiosu AM,Benguș A,Ladic A,Klarin I,Bove V,Busuioc B,Rimbaș M,Rustemovic N,Mateescu B,Jovanovic I,Costamagna G

    更新日期:2020-02-01 00:00:00

  • Impact of the COVID-19 pandemic on gastrointestinal endoscopy in the Netherlands: analysis of a prospective endoscopy database.

    abstract:BACKGROUND: COVID-19 has dramatically affected gastrointestinal endoscopy practice. We aimed to investigate its impact on procedure types, indications, and findings. METHODS: We retrospectively analyzed endoscopies performed in 15 Dutch hospitals by comparing periods 15 March to 25 June of 2019 and 2020 using the pros...


    pub_type: 杂志文章


    authors: Lantinga MA,Theunissen F,Ter Borg PCJ,Bruno MJ,Ouwendijk RJT,Siersema PD,Trans.IT foundation study group.

    更新日期:2021-02-01 00:00:00

  • Transcolonoscopic extraperitoneal cecostomy. A new therapeutic and technical proposal.

    abstract::The authors propose a new technique of decompression of the colon consisting in percutaneous cecostomy with previous extraperitonization of the cecum under colonoscopic orientation. The technique permits decompression of the entire colon through the insertion of a ceco-anal multiperforated Levine tube on withdrawing t...


    pub_type: 杂志文章


    authors: Ganc AJ,Netto AJ,Morrell AC,Plapler H,Ardengh JC

    更新日期:1988-11-01 00:00:00

  • Detection of early neoplasia in Barrett's esophagus using lectin-based near-infrared imaging: an ex vivo study on human tissue.

    abstract:BACKGROUND AND STUDY AIMS:Endoscopic surveillance for Barrett's esophagus (BE) is limited by long procedure times and sampling error. Near-infrared (NIR) fluorescence imaging minimizes tissue autofluorescence and optical scattering. We assessed the feasibility of a topically applied NIR dye-labeled lectin for the detec...


    pub_type: 杂志文章


    authors: Neves AA,Di Pietro M,O'Donovan M,Waterhouse DJ,Bohndiek SE,Brindle KM,Fitzgerald RC

    更新日期:2018-06-01 00:00:00

  • Small-bowel endoscopy.

    abstract::An overview of the scientific literature on small-bowel enteroscopy demonstrates that sonde enteroscopy is becoming more and more limited in its indications. Push enteroscopy is now a well-accepted modality for evaluation of the patient with small-bowel disease, including those with undiagnosed causes for gastrointest...


    pub_type: 杂志文章,评审


    authors: Waye JD

    更新日期:1999-01-01 00:00:00

  • Impact of double-balloon endoscopy on the diagnosis of jejunoileal involvement in primary intestinal follicular lymphomas: a case series.

    abstract::In recent years, primary gastrointestinal follicular lymphoma has been increasingly detected in the duodenum on esophagogastroduodenoscopy (EGD). Primary gastrointestinal follicular lymphomas are frequently distributed to multiple sites in the gastrointestinal tract. Therefore, investigation into the spread of follicu...


    pub_type: 杂志文章


    authors: Higuchi N,Sumida Y,Nakamura K,Itaba S,Yoshinaga S,Mizutani T,Honda K,Taki K,Murao H,Ogino H,Kanayama K,Akiho H,Goto A,Segawa Y,Yao T,Takayanagi R

    更新日期:2009-02-01 00:00:00

  • Beyond white light: optical enhancement in conjunction with magnification colonoscopy for the assessment of mucosal healing in ulcerative colitis.

    abstract::Background and study aim The I-SCAN optical enhancement (OE) system with magnification is a recently introduced combination of optical and digital electronic virtual chromoendoscopy, which enhances mucosal and vascular details. The aim of this pilot study was to investigate the use of I-SCAN OE in the assessment of in...


    pub_type: 杂志文章


    authors: Iacucci M,Kiesslich R,Gui X,Panaccione R,Heatherington J,Akinola O,Ghosh S

    更新日期:2017-06-01 00:00:00

  • Endoscopic hemostasis in sphincterotomy-induced hemorrhage: its efficacy and safety.

    abstract:BACKGROUND AND STUDY AIMS:Hemorrhage is induced in approximately 0.5-12% of endoscopic biliary sphincterotomy (ES) procedures. We prospectively investigated the risk factors for ES-induced hemorrhage and evaluated the safety as well as the effectiveness of endoscopic hemostasis. PATIENTS AND METHODS:The study included...


    pub_type: 临床试验,杂志文章


    authors: Kim HJ,Kim MH,Kim DI,Lee HJ,Myung SJ,Yoo KS,Park ET,Lim BC,Seo DW,Lee SK,Min YI

    更新日期:1999-08-01 00:00:00