Magnifying chromoendoscopic findings of early gastric cancer and gastric adenoma.

Abstract:

PURPOSE:In the field of colorectal cancer and adenoma, Kudo's classification of pit pattern with magnifying chromocolonoscopy using crystal violet (CV) staining is now accepted. Magnifying endoscopy using narrow band imaging has been used for the diagnosis of gastric carcinoma; the characteristic findings of microvascular patterns have been demonstrated. However, there was limited information on magnified endoscopic findings with CV staining for gastric neoplasms in terms of their pit patterns. METHODS:Magnifying chromoendoscopy with CV was performed in 175 patients with early gastric cancer and 18 with gastric adenoma, prior to treatment. Surface patterns of gastric tumors were classified into five types: (1) long tubular pit pattern, (2) irregular size pit pattern, (3) small round pit pattern, (4) destroyed pit pattern, and (5) non-structural pattern. RESULTS:Long tubular pit pattern was most common in gastric adenoma. Well differentiated adenocarcinoma and papillary adenocarcinoma tended to show different size of pit pattern or destroyed pit pattern. Small round pit pattern was most commonly seen in moderately differentiated adenocarcinoma. Non-structural pattern was most frequently observed in poorly differentiated adenocarcinoma and signet ring cell carcinoma (P < 0.0001). CONCLUSION:For gastric neoplasms, magnifying endoscopy may help predict histopathological type.

journal_name

Dig Dis Sci

authors

Ohnita K,Isomoto H,Shikuwa S,Yamaguchi N,Nakayama T,Nishiyama H,Okamoto K,Fukuda E,Takeshima F,Hayashi T,Kohno S,Nakao K

doi

10.1007/s10620-011-1638-6

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

2715-22

issue

9

eissn

0163-2116

issn

1573-2568

journal_volume

56

pub_type

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