Three-dimensional whole-brain perfused blood volume imaging with multimodal CT for evaluation of acute ischaemic stroke.


AIM:To determine the diagnostic value of integrating three-dimensional perfused blood volume (3D PBV) with multimodal computed tomography (CT) [non-enhanced CT (NECT), CT perfusion (CTP), and CT angiography (CTA)] in acute ischaemic stroke. MATERIALS AND METHODS:NECT, CTP, and CTA were performed in 25 acute ischaemic stroke patients. The ischaemia detection rate of 3D PBV was compared with the results of baseline NECT and CTP. The correlation of ischaemic lesion volume between 3D PBV, CTP images, and follow-up NECT were analysed. RESULTS:NECT demonstrated ischaemic signs in 12 of 25 patients with proven infarction. CTP maps of cerebral blood flow (CBF), cerebral blood volume (CBV), and time to peak (TTP) all demonstrated perfusion deficits in 21 of 25 patients. However, 3D PBV demonstrated perfusion deficits in all of the 25 patients. Among the 25 patients, a strong correlation was found between PBV and the follow-up NECT infarct (r = 0.858). The correlation between CTP and the follow-up NECT infarct as following: CBF (r = 0.718), CBV (r = 0.785), and TTP (r = 0.569). In 14 thrombolytic patients, strong correlation was found between the ischaemic volume on 3D PBV and follow-up NECT (r = 0.798). CONCLUSION:In acute stroke patients, the combination of 3D PBV and multimodal CT (NECT, CTP, and CTA) can improve the detection rate of ischaemia and enable assessment of the full extent of ischaemia, which correlates well with follow-up NECT.


Clin Radiol


Clinical radiology


Lu J,Zhang M,Cao Y,Ma Q,Chen J,Ji X,Li K




Has Abstract


2011-06-01 00:00:00














  • Mycobacterial infections: still a millennium bug--the imaging features of mycobacterial infections.

    abstract::Mycobacterial infection is re-emerging as a major health care concern. Although Mycobacterium tuberculosis(MTB) is still the most important pathogen, atypical mycobacterium (AMB) infections are becoming increasingly common. We present a pictorial review of the imaging features of these infections in the chest, abdomen...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审


    authors: Koh DM,Bell JR,Burkill GJ,Padley SP,Healy JC

    更新日期:2001-07-01 00:00:00

  • The role of magnetic resonance imaging techniques in the evaluation of orbital and ocular disease.

    abstract::Technical developments have resulted in a great improvement in the quality of magnetic resonance imaging (MRI) of the orbit. With surface coil data acquisition spatial resolution of less than a millimetre can now be achieved, and contrast discrimination is such that the cortex and nucleus of the lens can be distinguis...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Worthington BS,Wright JE,Curati WL,Steiner RE,Rizk S

    更新日期:1986-05-01 00:00:00

  • Solitary plasmacytoma of the frontal bone.

    abstract::We report a case of a solitary, painless, lytic lesion in the frontal bone in an otherwise asymptomatic patient. This was investigated with plain radiographs, computed tomography (CT), angiography and finally biopsy. Histology showed it to be a plasmacytoma. The radiological features of this lesion are discussed. Soli...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Wilson P,Chumas P,van der Walt JD

    更新日期:1990-10-01 00:00:00

  • The sonographic appearances of breast implant rupture.

    abstract::Implant rupture is a common late complication of breast implant procedures. Ruptures are often silent and difficult to diagnose clinically. This review demonstrates normal appearances and sonographic signs of implant rupture. Breast sonologists should be aware of these signs and pitfalls in interpretation when imaging...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审


    authors: Lake E,Ahmad S,Dobrashian R

    更新日期:2013-08-01 00:00:00

  • Renal adenomas.

    abstract::In presenting five new cases of renal adenomas the authors describe the general nature of these rare tumours. If the small adenoma corresponding to microscopic forms is frequent, the large adenoma is rare and always solitary. Haematuria and pain are the most common signs. The classic criterion of non-malignancy in a s...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Bruneton JN,Ballanger P,Ballanger R,Delorme G

    更新日期:1979-05-01 00:00:00

  • Magnetic resonance imaging of the shoulder: assessment of effectiveness.

    abstract:OBJECTIVES:To quantify how magnetic resonance imaging (MRI) influences clinicians' diagnosis, diagnostic confidence and management plans in patients with shoulder problems. To investigate whether such changes are associated with an improvement in health. METHODS:A prospective observational study on all patients referr...

    journal_title:Clinical radiology

    pub_type: 临床试验,杂志文章


    authors: Blanchard TK,Mackenzie R,Bearcroft PW,Sinnatamby R,Gray A,Lomas DJ,Constant CR,Dixon AK

    更新日期:1997-05-01 00:00:00

  • There's a hole in my symphysis -- a review of disorders causing widening, erosion, and destruction of the symphysis pubis.

    abstract::The symphysis pubis is demonstrated on many conventional radiographic and cross-sectional examinations and abnormality of the symphysis pubis is a common imaging finding with numerous possible causes. Many significant disorders that affect the symphysis pubis cause it to appear widened, eroded, or destroyed on imaging...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审


    authors: Budak MJ,Oliver TB

    更新日期:2013-02-01 00:00:00

  • Case report: an unusual association of a rectovaginal fistula with the Currarino triad.

    abstract::Currarino et al. in 1981 described an association between an anterior sacral defect, congenital anorectal stenosis or another type of low anorectal malformation and a presacral mass. We are only aware of one previous report in the English literature of the association of a rectovaginal fistula with this triad and to o...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Lang IM,Wilson BP

    更新日期:1994-04-01 00:00:00

  • Clinical features and cardiovascular magnetic resonance characteristics in Danon disease.

    abstract:AIMS:To investigate the clinical spectrum, cardiovascular magnetic resonance imaging (cMRI) characteristics, including T1 and extracellular volume fraction, and outcomes of Danon disease to facilitate further understanding of the phenotype of patients with Danon disease. MATERIALS AND METHODS:The study comprised six m...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: He J,Xu J,Chen L,Ji K,Fan X,Zhao S,Lu M

    更新日期:2020-09-01 00:00:00

  • Radiology reports: a quantifiable and objective textual approach.

    abstract:AIM:To examine the feasibility of using automated lexical analysis in conjunction with machine learning to create a means of objectively characterising radiology reports for quality improvement. MATERIALS AND METHODS:Twelve lexical parameters were quantified from the collected reports of four radiologists. These inclu...

    journal_title:Clinical radiology

    pub_type: 杂志文章,多中心研究


    authors: Scott JA,Palmer EL

    更新日期:2015-11-01 00:00:00

  • Advances in computed radiography systems and their physical imaging characteristics.

    abstract::Radiological imaging is progressing towards an all-digital future, across the spectrum of medical imaging techniques. Computed radiography (CR) has provided a ready pathway from screen film to digital radiography and a convenient entry point to PACS. This review briefly revisits the principles of modern CR systems and...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审


    authors: Cowen AR,Davies AG,Kengyelics SM

    更新日期:2007-12-01 00:00:00

  • Normal neuroanatomical variants that may be misinterpreted as disease entities.

    abstract::Variations of normal development and benign incidental anomalies are frequently observed on diagnostic neuroimaging. It is important these are recognised for what they are, as misinterpretation may result in unnecessary further investigation, follow-up imaging and anxiety. In this article, we review benign intracrania...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审


    authors: Ramji S,Touska P,Rich P,MacKinnon AD

    更新日期:2017-10-01 00:00:00

  • Retrospective evaluation and dating of non-accidental rib fractures in infants.

    abstract:AIM:To describe the sequential appearance of healing rib fractures on initial and follow-up radiographs using published guidelines in approximating the age of rib fractures in infants with the aim of establishing a more objective method of dating rib fractures by measuring the thickness of the callous formation. MATER...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Sanchez TR,Nguyen H,Palacios W,Doherty M,Coulter K

    更新日期:2013-08-01 00:00:00

  • The left ascending lumbar vein: a potential pitfall in CT diagnosis.

    abstract::A communication between the left ascending lumbar vein and the left renal vein may be mistaken for a para-aortic mass on abdominal computed tomography due to a localised dilatation at the confluence of these veins. The use of contiguous closely collimated sections and the injection of intravenous contrast medium overc...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Meanock CI,Ward CS,Williams MP

    更新日期:1988-09-01 00:00:00

  • Thrombolysis of the occluded prosthetic graft with tissue-type plasminogen activator--technique, results and problems in 23 patients.

    abstract::Over a 12 month period all patients but one presenting to our hospital with occluded prosthetic grafts were treated by thrombolysis using local pulsed administration of tissue-type plasminogen activator (t-PA). There were 30 interventions in 23 patients but in one patient no thrombolytic was given after aspiration of ...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Guest P,Buckenham T

    更新日期:1992-12-01 00:00:00

  • Iatrogenic femoral artery pseudoaneurysms--a review of current methods of diagnosis and treatment.

    abstract::The common femoral artery is commonly used as arterial access for a wide range of radiological and cardiological procedures. Pseudoaneurysm formation is the most common arterial complication of femoral artery catheterization, and is diagnosed using colour Doppler ultrasound. Ultrasound-guided thrombin injection has re...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审


    authors: Ahmad F,Turner SA,Torrie P,Gibson M

    更新日期:2008-12-01 00:00:00

  • Effect of intravenous contrast agent volume on colorectal cancer vascular parameters as measured by perfusion computed tomography.

    abstract:AIM:To determine the effect of two different contrast agent volumes on quantitative and semi-quantitative vascular parameters as measured by perfusion computed tomography (CT) in colorectal cancer. MATERIALS AND METHODS:Following ethical approval and informed consent, eight prospectively recruited patients with proven...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Goh V,Bartram C,Halligan S

    更新日期:2009-04-01 00:00:00

  • Low grade stage I and II non-Hodgkin's lymphoma: results of treatment and relapse pattern following therapy.

    abstract::Sixty-four patients (37 stage I and 27 stage II) with low grade non-Hodgkin's lymphoma were treated by surgical excision alone (two patients) or with radiotherapy (53 patients), chemotherapy (five patients) or both (four patients). Actuarial survival was 80.7% at 5 years and 77.9% at 10 years. Actuarial recurrence-fre...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Taylor RE,Allan SG,McIntyre MA,Kerr GR,Taylor AJ,Ritchie GL,Leonard RC

    更新日期:1988-05-01 00:00:00

  • The ultrasound diagnosis of hydatidiform mole.

    abstract::Experience with ultrasound compound 'B' scanning in 18 cases of hydatidiform mole is presented. The scan appearances are analysed with respect to the presence or absence of transonic areas, and to the uniformity of echogenicity elsewhere in the uterus. The differential diagnosis is discussed. The commonest appearance ...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Baird AM,Beckly DE,Ross FG

    更新日期:1977-11-01 00:00:00

  • Case report: infiltrating syringomatous adenoma of the breast--appearances on mammography and ultrasonography.

    abstract::Infiltrating syringomatous adenoma is a recently-recognized locally-invasive breast neoplasm which clinically may mimic carcinoma. We describe bilateral syringomatous adenomata in a screened patient, indistinguishable from carcinoma on mammography and ultrasound examination. The clinical and pathological features whic...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Coulthard A,Liston J,Young JR

    更新日期:1993-01-01 00:00:00

  • Radiation-induced sarcoma of bone: clinical and radiographic findings in 43 patients irradiated for soft tissue neoplasms.

    abstract::Sarcomas rarely follow irradiation of benign lesions of bone as the dangers of this form of therapy is well recognised. Forty-three patients with soft tissue neoplasms - mainly carcinoma - were irradiated and developed sarcomas in the radiation field. Twenty-four of these patients were seen at this centre in the last ...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Smith J

    更新日期:1982-03-01 00:00:00

  • The radiology of Askin tumours.

    abstract::The Askin tumour is a highly malignant primitive neuroectodermal tumour (PNET) of the chest wall occurring in children and young adults. We describe three cases to illustrate the clinical and radiological aspects of this tumour, which are not well documented. Patients present with a chest wall mass, pain and constitut...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审


    authors: Saifuddin A,Robertson RJ,Smith SE

    更新日期:1991-01-01 00:00:00

  • Retrograde or antegrade double-pigtail stent placement for malignant ureteric obstruction?

    abstract:AIM:To determine the optimum approach for double-pigtail stent placement in malignant ureteric obstruction. PATIENTS AND METHODS:Retrograde stent placement was attempted in a consecutive series of patients presenting with malignant ureteric obstruction. If retrograde stent placement was unsuccessful, percutaneous neph...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Uthappa MC,Cowan NC

    更新日期:2005-05-01 00:00:00

  • Leptomeningeal cyst of the orbit presenting with pulsatile exophthalmos.

    abstract::The case of a 64-year-old man who presented with unilateral pulsatile exophthalmos is described. A defect in the supero-medial wall of the orbit and an extraconal low density mass were demonstrated by orbital radiographs and CT. Positive contrast CT cisternography confirmed the diagnosis of a leptomeningeal cyst. ...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Abernethy LJ,Whittle IR,Sellar RJ

    更新日期:1989-09-01 00:00:00

  • Computed tomography in blunt abdominal trauma: an analysis of clinical management and radiological findings.

    abstract::We have retrospectively assessed the computed tomography (CT) findings in 92 patients suffering severe blunt abdominal trauma. Surgical findings and clinical follow-up were correlated with the CT findings. In nine patients CT was first used after emergency surgery and provided baseline data which was useful for furthe...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Padhani AR,Watson CJ,Calne RY,Dixon AK

    更新日期:1992-11-01 00:00:00

  • The current status of digital mammography.

    abstract::Digital imaging has shown rapid advances in recent years. Various different digital mammography systems are now available for clinical use. Digital mammography does have clear advantages over traditional screen film mammography, but this is yet to convincingly translate into improved cancer detection rates. This revie...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审


    authors: James JJ

    更新日期:2004-01-01 00:00:00

  • Case report: multiple myeloma--a rare presentation.

    abstract::An unusual case of multiple myeloma is reported in a 61-year-old man presenting with hepatomegaly and multiple hypoechoic lesions in the liver seen on ultrasound. Following cytotoxic chemotherapy the size and number of the lesions within the liver had significantly reduced. ...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Curtis JM,Pellegrini V,Tappin JA

    更新日期:1995-01-01 00:00:00

  • Feasibility of three-dimensional constructive interference in steady state sequences for evaluating the anterolateral ligament.

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    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Zhu Y,Qiu X,Yu T,Zhang C,Zhao X,Duan F,Hao D

    更新日期:2019-12-01 00:00:00

  • Case report: in utero diagnosis of a vein of Galen aneurysm using colour flow Doppler.

    abstract::We report the ante-natal diagnosis of a vein of Galen aneurysm using colour flow Doppler at 33 weeks gestation. Ultrasound demonstrated a midline, tubular, echo-free structure superior to the thalamus extending posteriorly. Venous flow was demonstrated within the structure using colour flow Doppler. The diagnosis was ...

    journal_title:Clinical radiology

    pub_type: 杂志文章


    authors: Evans AJ,Twining P

    更新日期:1991-10-01 00:00:00

  • Colonic preparation with Picolax: patient tolerance and approaches to fluid replacement.

    abstract::Sodium picosulphate (Picolax) is widely used for bowel preparation prior to colonic investigation or surgery. The most troublesome side effect reported is headache, which has been thought to be due to dehydration. In a prospective randomized study we investigated the incidence of adverse effects in patients given Pico...

    journal_title:Clinical radiology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Lawrance JA,Massoud TF,Creasy TS,Shatwell W,Mason A,Nolan DJ

    更新日期:1994-01-01 00:00:00