Reproducibility of fMRI activations during a story listening task in patients with schizophrenia.

Abstract:

:A prerequisite to longitudinal fMRI studies in schizophrenia is the knowledge on fMRI signal reliability in schizophrenia patients. We assessed the reproducibility of activations elicited by two fMRI sessions, which were 21 months apart, of a story listening paradigm in 10 schizophrenia patients and 10 healthy subjects. In both groups, we observed a high degree of spatial overlap of activation maps as well as a good reproducibility of signal variations assessed on a voxel-wise basis in temporal areas underlying early stages of language processing. Task performance, assessed through a comprehension questionnaire, had no impact on the activation reproducibility.

journal_name

Schizophr Res

journal_title

Schizophrenia research

authors

Maïza O,Mazoyer B,Hervé PY,Razafimandimby A,Dollfus S,Tzourio-Mazoyer N

doi

10.1016/j.schres.2011.01.025

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

98-101

issue

1-3

eissn

0920-9964

issn

1573-2509

pii

S0920-9964(11)00059-4

journal_volume

128

pub_type

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